By Anora Mahmudova, MarketWatch

NEW YORK (MarketWatch) -- U.S. stocks ended Tuesday generally higher with the Nasdaq Composite recording its eighth consecutive session of gains, the longest since July 2013.

The Dow Jones Industrial Average (DJI) defied the general trend, ending lower after component Coca-Cola Co. (KO) reported disappointing earnings. Also weighing: the Empire State manufacturing activity index dropped by more than expected while a gauge of confidence among home builders dove in February.

The S&P 500 index (SPX) closed 2.13 points, or 0.1%, higher at 1,840.76, extending gains from the previous two sessions. Seven of 10 main sectors rose, with health-care stocks in the lead.

The Nasdaq Composite (RIXF) rose 28.76 points, or 0.7%, to 4,272.78. The tech-heavy index outperformed other indexes so far this year, gaining 2.6% since the end of last year. Read the recap of our stock market live blog.

Markets were closed on Monday for the Presidents Day holiday. Last week, stocks registered their best weekly gains of the year, and the Nasdaq Composite closed at a July 2000 high.

"It is not surprising for markets to have a slow day such as today, especially after big rally at the end of the year followed by a pullback in January," said Colin Cieszynski, senior market analyst at CMC Markets, based in Toronto.

"Investors seem to treat weak economic manufacturing and housing reports with understanding that weather played a big role in the slowdown," he added.

Empire State, home builders

Manufacturing activity in the New York region gave up most of the strong gains made during the prior month although it remained in positive territory, according to data released Tuesday. The report fits a picture of a manufacturing sector struggling with severe winter weather. The ISM index for the U.S. showed manufacturers suffered from the January chill last month.

A gauge of confidence among home builders plunged in February, dropping to the lowest level in nine months, led by weaker views on present sales of single-family homes, according to data released Tuesday.

The housing-market index dropped to 46 this month from 56, signaling that builders, generally, are pessimistic about sales trends, according to the National Association of Home Builders/Wells Fargo, which cited "unusually severe weather conditions," among other factors.

Movers: Forest Labs, Tesla, BlackBerry

Big movers on Wall Street Tuesday include Forest Laboratories Inc. (FRX), with shares surging 28% on news that Actavis PLC (ACT) will buy its New York-based rival in a cash-and-stock deal worth $25 billion. Actavis rose 5%.

Shares of Coca-Cola were down 3.8% after the beverage company's fourth-quarter profit and revenue came in below analyst forecasts.

Read Jim Jelter: Why Coke needs Green Mountain

Shares of Tesla Motors Inc.(TSLA) were up 2.8% to $203.70 Tuesday, a record close, after a report that Apple Inc.'s (AAPL) top deal maker met with the car company's CEO, Elon Musk, last year as part of its quest to snap up companies to fuel growth. Also, R.W. Baird analysts raised their price target on Tesla to $215.

BlackBerry Ltd. (RIMM) was up 5.4% following news Friday that billionaire fund manager Dan Loeb took a stake in the company as part of his investment in struggling device makers.

FBR & Co. also upgraded BlackBerry's stock to market perform from underperform, with analyst Scott Thompson writing in a note: "We expect the company's liquid assets and early positive momentum could limit downside in shares in the near term."

Prana Biotechnology Ltd. (PRAN) soared 39% to $10.10 after the pharmaceutical company said it met the endpoint for one phase of a clinical study testing its treatment for Huntington's disease.

After hours: Herbalife

Herbalife (HLF) shares, which closed 3.8% higher, rallied as much 4% in aftermarket action after the company reported estimate-beating fourth-quarter results. Herbalife said earlier this month that it plans to offer $1 billion in convertible notes and use the proceeds to buy back shares.

Overseas: Bank of Japan boost

In Asia, Japan's Nikkei 225 index rallied 3.1% after the Bank of Japan said it would double incentives designed to increase bank lending. Other Asian markets closed mixed.

European stock markets ended marginally higher and stayed in negative territory after a disappointing reading on German economic sentiment. Gold prices edged higher while the dollar and oil prices rose.

More must-reads from MarketWatch:

Soros doubles a bearish bet on the S&P 500, to the tune of $1.3 billion

Investor prisoner, volume control, when Apple met Tesla and Forest Labs

'Downton Abbey' economy, here we come, warns Larry Summers

You're invited to ... Bitcoin: Boom and Bust

Subscribe to WSJ: http://online.wsj.com?mod=djnwires

Prana Biotechnology (ASX:PBT)
Historical Stock Chart
From Oct 2024 to Nov 2024 Click Here for more Prana Biotechnology Charts.
Prana Biotechnology (ASX:PBT)
Historical Stock Chart
From Nov 2023 to Nov 2024 Click Here for more Prana Biotechnology Charts.