UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

NOTICE OF EFFECTIVENESS

Effective Date: December 22, 2015
Form: S-3
CIK: 0001072379
Company Name: NORTHWEST BIOTHERAPEUTICS INC
File Number: 333-207976
Northwest Biotherapeutics (QB) (USOTC:NWBO)
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