PRISM MarketView Spotlights Quoin Pharmaceuticals CEO Dr. Michael Myers as Specialty Pharma Shares News of Highly Positive Interim Data in Most Advanced, Comprehensive Netherton Syndrome Trials
January 07 2025 - 2:29PM
PRISM MarketView has released an exclusive interview with
Quoin Pharmaceuticals Ltd. (NASDAQ: QNRX) CEO Dr. Michael Myers,
who shares the company’s notable interim data in its ongoing
Netherton Syndrome clinical trials. Quoin, a clinical-stage
specialty pharmaceutical company focused on rare and orphan
diseases, is addressing unmet medical needs for those with
Netherton Syndrome (NS), a rare and sometimes fatal skin disease
for which there is currently no approved treatment and no cure.
The company recently announced highly positive interim clinical
data —with no safety concerns—from one of its ongoing Netherton
Syndrome clinical studies examining the potential of QRX003, a
topical lotion formulated with a proprietary delivery technology
that targets the underlying cause of the disease. Quoin’s QRX003
program involves the most advanced NS trials being conducted under
an open Investigational New Drug (IND) application.
During a discussion with PRISM MarketView, Dr. Myers noted the
“life-changing potential this drug has for the Netherton community”
and that “coupled with the other clinical data we have generated to
date, we are very optimistic that we have a product that
effectively treats this disease.”
The first subject dosed twice daily demonstrated marked
improvements across all measured clinical endpoints after 12 weeks
of treatment, including dramatic reduction in the skin’s visible
redness, scaling and inflammation. The company has published images
of the subject’s remarkable progress [here],
further underscoring the therapy’s potential. Notably, the Worst
Itch Numeric Rating Scale (WINRS) declined from 7 to 2, reflecting
significant relief from one of Netherton Syndrome’s most
debilitating symptoms.
In addition, Dr. Myers discussed recent FDA clearance for
Quoin’s whole-body clinical study, to be led by Dr. Amy Paller at
Northwestern University, which will evaluate the safety and
efficacy of QRX003 when applied twice-daily to over 80% of the body
surface area, compared to the approximately 20% being treated in
ongoing studies. The most extensive application of QRX003 to date,
this study is designed to simulate real-world use and generate
critical safety and efficacy data to supplement the company’s
submission for regulatory approval.
Other highlights for Quoin include a new pediatric study for
QRX003 as well as expansion of the specialty pharma’s international
footprint to ensure access to diverse patient populations and to
generate robust, global data.
Dr. Myers concluded, “Looking ahead, Quoin is committed to
ensuring that every patient, no matter where they are in the world,
will have access to our product once approved. This commitment
drives our efforts to advance QRX003 as the first FDA-approved
treatment for Netherton Syndrome, meeting the needs of this
underserved community.”
The full interview can be found
at: https://prismmarketview.com/quoin-pharmaceuticals-reveals-highly-positive-interim-data-in-most-advanced-and-comprehensive-netherton-syndrome-clinical-trials-under-open-ind/
About Quoin Pharmaceuticals Ltd.
Quoin Pharmaceuticals Ltd. is an emerging specialty
pharmaceutical company focused on developing and commercializing
therapeutic products that treat rare and orphan diseases. We are
committed to addressing unmet medical needs for patients, their
families, communities and care teams. Quoin’s innovative pipeline
comprises three products in development that collectively have the
potential to target a broad number of rare and orphan indications,
including Netherton Syndrome, Peeling Skin Syndrome, Palmoplantar
Keratoderma, Epidermolysis Bullosa and others. For more
information, go to: www.quoinpharma.com.
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A photo accompanying this announcement is available at
https://www.globenewswire.com/NewsRoom/AttachmentNg/69695fb6-060b-486d-9bf0-ff2f68fd1ec2
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