TIDMEDEN

RNS Number : 5376E

Eden Research plc

28 February 2020

28 February 2020

Eden Research Plc

("Eden" or "Company")

Placing, Subscription & Open Offer

Eden Research plc (AIM: EDEN), the AIM-quoted company that develops and supplies breakthrough biopesticide products and natural microencapsulation technologies to the global crop protection, animal health and consumer products industries, today announces that it has conditionally raised GBP10.1 million (before expenses) by way of a Placing and Subscription of new Ordinary Shares at the Issue Price of 6p per share to certain institutional and other investors. Furthermore, to enable other Shareholders not able to participate in the Placing an opportunity to subscribe for additional Ordinary Shares, the Company is proposing to raise up to an additional GBP0.5 million (before expenses) by way of an Open Offer made to Qualifying Shareholders of up to 8,287,573 new Ordinary Shares at the Issue Price.

Eden is currently the only UK-quoted company focused on biopesticides for sustainable agriculture and is well positioned to capitalise on the rapidly growing biopesticides market, which is projected to be worth over GBP10 billion by 2025. The Company expects to apply the net proceeds of the Fundraise to advance the development, registration and commercialisation of new key product categories, including new insecticide formulations and seed treatments.

Transaction Highlights

-- Placing of 151,666,834 new Ordinary Shares at the Issue Price with new and existing investors to raise GBP9.1 million (before expenses)

-- Subscription for 16,666,500 new Ordinary Shares by Sipcam Oxon S.p.A. at the Issue Price to raise in aggregate GBP1.0 million (before expenses)

-- Open Offer to Qualifying Shareholders at the Issue Price to raise up to an additional GBP0.5 million (before expenses)

   --      The Directors intend to use the net proceeds from the Fundraise for the following purposes: 

o c. GBP6.0 million to develop and commercialise the Company's first insecticide products and seed treatments; and

o c. GBP2.0 million to develop use of Sustaine ä with traditional agrochemicals; and

o c. GBP2.0 million to expand the Company's product portfolio in seed treatments, broad-acre crops and the home and garden market.

The Company will shortly be posting a Notice of General Meeting and an accompanying circular (the "Circular") to existing shareholders following this announcement. All relevant documents will be available to download at https://www.edenresearch.com/ .

Sean Smith, Chief Executive Officer of Eden, said :

"Eden has been making good progress with the commercialisation of our products and technologies. As momentum continues to build, we remain focussed upon providing sustainable solutions for global agriculture. Furthermore, we are eager to accelerate the commercialisation of new products for new categories including insecticides and seed treatments. Now is the right time to invest and capitalise on the opportunities in our pipeline. We have a clear ambition to be a global leader in sustainable chemistry, and this fundraise will allow us to enter new and significant markets from a position of strength.

The outlook for the biopesticides market is undoubtedly positive, with a clear demand from a growing consumer market for sustainably grown produce and a notable shift towards greener farming practices. Eden's biopesticide solutions combine high levels of efficacy that are comparable to synthetic pesticides and are aligned with the direction of regulatory travel, which has seen restrictions and, in some cases, the removal of conventional products from the market."

Introduction

The Company announces a proposed Placing, Subscription and Open Offer, pursuant to which it proposes to raise, subject to certain conditions (i) GBP10.1 million (before expenses) by the conditional Placing and Subscription of 168,333,334 new Ordinary Shares at the Issue Price to certain institutional and other investors including Sipcam; and (ii) up to approximately GBP0.5 million (before expenses) by way of an Open Offer made to Qualifying Shareholders of up to 8,287,573 new Ordinary Shares at the Issue Price.

The net proceeds of the Placing, Subscription and Open Offer will be used to advance the development, registration and commercialisation of new product categories, including new insecticide formulations and seed treatments, as well as to provide additional working capital for the Group associated with the new development areas, as described in more detail in this announcement. The Placing, Subscription and Open Offer are conditional (amongst other things) upon the Company obtaining approval from its Shareholders to disapply statutory pre-emption rights and to grant the Board authority to allot and issue the New Ordinary Shares. The Issue Price equates to a discount of 23.9 per cent to the closing middle market price of 7.88 pence per Ordinary Share on 27 February 2020 (being the last Business Day before publication of this Announcement).

Background to and rationale for the Fundraise

The Company's vision is to become the leader in sustainable bioactive products and the Board believes Eden is well positioned to capitalise on the global shift towards more environmentally friendly methods of crop protection, as demonstrated by the European Chemicals Agency's proposed EU-wide restriction on the use of intentionally added microplastic particles. Eden is currently the only UK-quoted company focused on biopesticides for sustainable agriculture. Eden develops and supplies innovative biopesticide products to the global crop protection market, using the Company's patented microencapsulation technology, Sustaine ä . Sustaine ä microcapsules are naturally sourced, plastic-free, biodegradable micro-spheres derived from yeast extract. Importantly, the Sustaine ä microencapsulation technology enables the technical viability of naturally occurring terpenes for use in commercial crop protection.

The Company is pursuing the Fundraise to continue to drive commercial progress and to build the foundations for the next stage of its development in significant markets. The Company intends to use the net proceeds from the Fundraise to (i) register and commercialise the Company's first insecticide product, (ii) develop the use of Sustaine ä with conventional agrochemicals, (iii) expand the Company's product portfolio and (iv) to capitalise on opportunities arising from its relationship with Corteva Agriscience.

Market Opportunity for Biopesticides

While the use of effective pesticides has been fundamental to the farming revolution over the last 100 years, governments and consumers have increasingly begun to acknowledge the risk to the environment and human health posed by conventional pesticides. This has led to the banning or restriction (especially in Europe) of some common pesticides such as Neonicotinoids and Chlorothalonil.

This has subsequently increased the use of biopesticides and, as a result, the biopesticides market is growing at a CAGR of approximately 15% per annum and is projected to be worth more than $10 billion by 2025.

Eden's biopesticide solutions solve a number of the issues of conventional pesticides. Using plant derived active ingredients that are generally accepted as safe by regulators around the world means that the products are not subject to residue limits, long per-harvest intervals and can be used as a post-harvest treatments, subject to regulatory approval.

In addition, the Company's yeast based Sustaine(TM) encapsulation technology allows Eden's products and conventional pesticides to be used without the presence of plastics. There are currently global concerns regarding the volume of micro-plastics in the environment and the impact their presence has on human health and wildlife. In response, there have been new regulations proposed which could restrict the intentional addition of plastic to pesticides, which has created a need for the major pesticide producers to actively look for alternative approaches to encapsulation of existing chemical treatments. These restrictions mean that the time and cost of bringing new agrochemical products to market has increased to around 10 to 12 years and approximately $300 million.

From a broader perspective, concerns regarding the impact on human health of pesticides has increased the consumer appetite for organic products and encouraged regulators to put stricter controls around spraying of crops and residue limits.

Another advantage of Eden's proposition is that its three EU-registered active ingredients, geraniol, eugenol and thymol, were all approved for use in organic farming in January 2020, following inclusion in the EU's Organic Production Regulation. Entry into the organic farming arena opens up new commercial opportunities for the Company and is relevant to all products that utilise the Company's three EU-registered active ingredients. In 2017, Organic farming covered 12.6 million hectares of agricultural land in the EU Member States, equivalent to 7% of the total utilised agricultural area. Between 2012-2017, land assigned for organic growing within these Member States increased by 25%. In two of the Company's key territories, Italy and Spain, the share of organic production totals 15.2% and 9.3% respectively.

Eden's Current Products and Technology

Sustaine ä - Microencapsulation Technology

Eden proposes to use part of the proceeds to actively develop formulations with traditional chemical products using its Sustaine ä microencapsulation technology. Following the Fundraise, it plans to undertake trials to demonstrate the range of benefits that Sustaine ä offers to potential partners.

By 2025 in the EU, pesticides containing synthetic polymer microplastics are likely to be severely restricted or banned entirely and removed from the market. The Directors believe that the only acceptable alternative is the substitution with biodegradable formulations. Reformulated products will likely need to be evaluated and registered within the five-year transition period.

Eden has developed a natural formulation technology, Sustaine(TM) using particles derived from natural yeast cells. The technology was originally developed as a drug delivery method for human health applications before Eden adapted it for use in the encapsulation of pesticides. By creating a stabilised aqueous emulsion, Sustaine ä enables the formulation of pesticides using a number of terpene based active ingredients which would not be functional without being encapsulated. The encapsulation provides for the sustained release of these ingredients when in contact with water and closing once dry, enabling their safe, more efficient use. The benefit of Sustaine ä is that it is cost effective, useful for a wide range of active ingredients, plastic-free, high capacity, robust, sustainable and facilitates reduced phytotoxicity.

Sustaine ä is a proven and viable solution to the microplastics problem in formulations requiring encapsulation. Even before the EU regulation of microplastics, the Company has a small number of projects underway where it is testing the compatibility of Sustaine ä with third-party active ingredients to determine whether benefits such as formulation stability, dose reduction or resistance management could be achieved. However, the new, proposed restriction of microplastic particles may open up a further, significant opportunity for Eden to deploy its Sustaine ä technology on a very large scale.

Mevalone ä - Fungicide Product

Eden's first biopesticide, Mevalone ä , is a fungicide used in the prevention and treatment of botrytis in table and wine grapes, as well as the control of powdery mildew on grapevines and, in certain territories, the treatment of botrytis on a range of crops ranging from kiwis to onions.

During 2016, Mevalone ä was approved and distribution was in place to cover four southern European countries and Kenya. The first commercial sales of Mevalone ä were made in the same year in Kenya, Greece, Italy and Spain. Approval in France for table and wine grapes followed in 2017. During 2018, the Company initiated the approval process for Mevalone ä and the three associated active substances (terpenes) with the US Environmental Protection Agency (EPA) and currently expects to receive approval during 2020. It is also currently undergoing the regulatory approval process in a number of additional countries, including key wine growing regions Australia and New Zealand.

In 2019, Mevalone ä received an emergency use authorisation in France for the treatment of postharvest storage diseases on apples. Over one third of apples produced in France go into storage, and it is under storage conditions that a number of diseases can develop. It has been demonstrated that Mevalone ä , when applied shortly before harvest, is effective at combating storage diseases and that the product provided a solution that met the requirements of growers where there is a lack of suitable commercially available alternatives.

The Company currently has distribution agreements for Mevalone ä with Sipcam and Sumi Agro for the major territories. A full list of the regulatory approvals for Mevalone ä can be found in the Appendix to the Chairman's letter.

Cedroz ä - Nematicide Product

In addition to Mevalone ä , Eden has developed a nematicide product which is used to tackle nematode infestations which can damage crops and affect yield. Nematodes are parasites that affect a wide range of crops grown in open fields and in greenhouses.

In 2016, Eden signed an exclusive distribution agreement with Eastman Chemical for the nematicide product which has since been branded Cedroz ä . Eastman acquired the rights to register and sell Cedroz ä in 29 countries. Cedroz ä recently received its first zonal approval from Malta in February 2019 and was granted approval for emergency use in Italy in April 2019. It has since been approved in Belgium and Mexico. Additional applications for Cedroz ä have been made for certain larger markets such as Italy, Spain and France. The Company also submitted an application for registration to the EPA in the US in 2018. A full list of the regulatory approvals for Cedroz ä can be found in the Appendix to the Chairman's letter.

The Corteva Agreement

The Fundraise will allow the Company to capitalise on opportunities arising from its relationship with Corteva Agriscience. Eden signed an exclusive evaluation agreement with Corteva Agriscience, the world's fourth largest agriculture input company, in January 2020 . Significantly for Eden, regulatory change led to the withdrawal of one of Corteva Agriscience's key seed treatment in the EU. Initial trials by Corteva Agriscience have shown strong results using Eden's products and formulation technology. Eden's formulation technology has been shown to be stable, environmentally friendly and complies with emerging EU regulations concerning polymers.

Further trials will be undertaken under a one-year evaluation agreement and, subject to the results, Corteva Agriscience and Eden will look to sign a distribution agreement for the EU, Russia, Ukraine and Turkey giving Eden the opportunity to capture a significant share of this market. The Directors estimate that, if successful, there is the opportunity to generate up to c. EUR40 million of revenue for Eden from European geographies alone (current market) from this product.

Insecticide Opportunity

The Company intends to use a proportion of the proceeds to pursue the registration and commercialisation of its first insecticide product. The funding will enable a more efficient and concurrent approach to registration as the Company will be able to run efficacy trials in parallel, rather than in sequence, which are necessary for regulatory product authorisations around the world. By funding these trials directly, it is expected that Eden will be able to fully control and ultimately commercially leverage its intellectual property and product authorisations. The Company may seek to appoint local distributors where appropriate, thereby optimising and significantly simplifying the value chain resulting in margin expansion.

The insecticide product will be an addition to the Company's current suite of products, and follows an assessment of various new product development opportunities, one of which addresses significant unmet needs in the agrochemical insecticide market. Using a combination of Eden's active ingredients, which are registered in the EU already, and various co-formulants, Eden has developed an effective insecticide product with good activity against multiple key insect pests including whitefly, aphids, thrips and mites, as proven in a number of Good Experimental Practice standard field trials undertaken by well-known Contract Research Organisations.

The Company has identified this market as having a strong need for an effective alternative to conventional insecticides due to strong consumer and regulatory pressure driven by persistence, bio-accumulation, toxicity and susceptibility to resistance. To open this significant market opportunity for Eden, the Company will need to complete a number of further efficacy and safety trials in target markets. The initial investment will target the highest value markets such as mites in the highest value crops (citrus, tree fruit and grapes).

 
 Estimated Market Sizes 
 (EURm)                   Mites     Whitefly   Thrips   Aphids    Total 
-----------------------  --------  ---------  -------  --------  -------- 
 US                       EUR159m   EUR5m      EUR59m   EUR107m   EUR330m 
 Europe (incl. Turkey)    EUR147m   EUR97m     EUR85m   EUR192m   EUR521m 
 Company estimates 
 

Product Portfolio Expansion

For some time, the Company has been aware of potential commercial opportunities in seed treatments and broad-acre crops. To date, investment in developing products for these areas of application has been limited due to general resource constraints. However, given the success that the Company has seen with the commercialisation of its existing products, it now wishes to expedite development of these additional product areas.

The funds will be used to undertake laboratory screening, formulation work and pot/field trials. This should, where successful, allow Eden to bring these products to a stage where they can be registered and commercialised through the Company's distribution channels.

Company Strategy

The Company's near-term focus is to maximize the opportunity for sales of its two approved products, Mevalone ä and Cedroz ä , the use of Sustaine ä with third party active ingredients, the exploitation of seed treatment opportunities with Corteva Agriscience and the development of its insecticide product. The Company continues to explore additional business line diversification including ongoing work with Bayer Animal Health, as well as potential for consumer product launches. In addition, the Company will seek to expand the crops and diseases treated by its products and will look to undertake further geographic diversification (seasonal and climatic variation).

Use of Proceeds

The Directors intend to use the net proceeds from the Fundraising of up to GBP10.0 million for the following purposes:

-- GBP6.0 million to develop and commercialise the Company's first insecticide product and seed treatments;

   --      GBP2.0 million to develop use of Sustaine ä with traditional agrochemicals; and 

-- GBP2.0 million to expand the Company's product portfolio in seed treatments, broad-acre crops and the home and garden.

Current Trading and Prospects

On 14 January 2020, the Company provided a trading update for the year ended 31 December 2019. The Company reported that revenue for the year is expected to be approximately GBP2.0 million (2018: GBP2.8 million) and operating loss for the year will be approximately GBP1.4 million (2018: loss of GBP0.5 million), in line with market expectations. The Company confirmed that GBP1.7 million of the GBP2.0 million of revenue was derived from product sales (2018: GBP1.6 million), achieved despite unfavourable growing conditions in the Southern EU, with milestone and upfront payments making up the balance.

The well-publicised hot and dry growing conditions across southern Europe during the peak 2019 growing season negatively impacted the development of Botrytis and this resulted in botryticide usage generally being impacted. Despite the resulting overall contraction of the botryticide market, product sales revenue increased as a whole compared to the previous year.

During 2020, the Company expects to build on the sales achieved in the territories where it had approvals during 2019 as well as seeing further sales from the territories where it announced new approvals at the end of last year (Belgium and Mexico). In addition, the Company expects to see sales arising from new approvals for Cedroz ä in Spain, Italy, France, Belgium, the Netherlands and the United Kingdom where the applications for registrations have now been outstanding from the early part of 2019 and the constituent active ingredients are already approved.

The Company also currently expects approval during 2020 of Mevalone ä and Cedroz ä from the EPA so that the products can be sold into the United States. However, these will constitute entirely new approvals and timing is harder to predict. Although the Company might expect to see some level of channel stocking, the overall levels of sales will depend in part on the timing during the year when the approvals come through in relation to the growing season.

Directors' participation, appointment rights and LTIP

Directors' participation in the Placing

As part of the Fundraise, certain Directors and their connected persons intend to subscribe (either personally or through a nominee) for an aggregate of 416,500 Placing Shares at the Issue Price. Details of the Placing Shares for which the Directors intend to subscribe (either personally or through a nominee) are displayed below:

 
                                                                  Number        Value of 
                                                              of Placing         Placing 
                                                                  Shares          Shares 
                                                  Number        intended        intended 
                                             of existing           to be           to be 
                                                Ordinary      subscribed      subscribed 
Name                Title                      Shares(#)          for(#)          for(#) 
                    Chief Executive 
Sean Smith           Officer                     433,393         183,333      GBP 11,000 
                    Chief Financial 
Alex Abrey           Officer                   1,152,824         150,000        GBP9,000 
Robin Cridland      Non-Executive Director        47,000          83,167       GBP 4,990 
 

# The number of Ordinary Shares presented in this table as being held or subscribed for by Directors refers to the number of Ordinary Shares held or subscribed for by them either personally or through a nominee.

LTIP

It is proposed that, following First Admission and Second Admission, the Company will implement a new long term incentive plan (LTIP) to award the performance of the executive management team. The new LTIP would replace the Company's existing LTIP, and is deemed a more appropriate scheme to incentivise management given the Company's stage of development. Pursuant to the new LTIP, the Company will grant options over 10.5 million new Ordinary Shares in Eden, at a strike price of 6p each, in the amounts of 6 million awarded to Sean Smith and 4.5 million awarded to Alex Abrey. The options will vest immediately and will lapse in three equal tranches in June 2022, June 2023 and June 2024. For the first five years following the grant of options, no shares arising from the exercise of these options may be sold unless the Company's prevailing share price is equal to or in excess of 10p. The LTIP will include a net cashless mechanism whereby a number of shares may be deducted from the participant's option pool upon exercise, equivalent to half the exercise cost based on the prevailing market price of Eden's Ordinary Shares, and provided the remaining exercise cost is paid in cash. The shares arising from exercise of options shall be subject to a one-year lock-in restriction, followed by a one-year orderly market restriction. Further details of the LTIP will be announced following First Admission and Second Admission once formally implemented.

Director appointment right

As part of their placing participation of 58,333,000 Placing Shares (amounting to approximately GBP3.5 million), BGF has been granted the right to appoint a director to the board of the Company for as long as it retains a minimum interest of five per cent. of the issued share capital of the Company.

Details of the Placing and the Subscription

Eden is proposing to raise GBP9.1 million (before expenses) pursuant to the Placing. The Placing has conditionally raised a total of approximately GBP5.2 million through the placing of the EIS/VCT Placing Shares and a total of approximately GBP3.9 million through the placing of the General Placing Shares. Admission of the Ordinary Shares to trading on AIM will occur over two Business Days to assist investors in the EIS/VCT Placing Shares to claim certain tax reliefs available to EIS and VCT investors.

Subject to, inter alia, the passing of the Resolutions at the General Meeting, the EIS/VCT Placing Shares are expected to be admitted to trading on or around on 19 March 2020, being one Business Day prior to admission to trading on AIM of the General Placing Shares and Subscription Shares, which are expected to be admitted to trading on AIM or around 20 March 2020 . The allotment of the EIS/VCT Placing Shares will be conditional on First Admission occurring. The allotment of the General Placing Shares will be conditional on Second Admission occurring. Shareholders and potential investors should be aware of the possibility that the First Admission and Second Admission may not occur.

Although the Company currently expects to satisfy the relevant conditions for EIS/VCT Placing Shares, and the Directors are not aware of any subsequent change in the qualifying conditions or the Company's circumstances that would prevent the EIS/VCT Placing Shares from being eligible for EIS and VCT investments on this occasion, neither the Directors nor the Company, nor Cenkos, nor any of their respective directors, officers, employees, affiliates or advisers give any warranty or undertaking or other assurance that relief will be available in respect of any investment in the EIS/VCT Placing Shares, nor do they warrant or undertake or otherwise give any assurance that the Company will conduct its activities in a way that qualifies for or preserves its status.

As the rules governing EIS and VCT reliefs are complex and interrelated with other legislation, if Shareholders, or other potential investors, are in any doubt as to their tax position, require more detailed information, or are subject to tax in a jurisdiction other than the United Kingdom, they should consult their professional adviser.

In addition, Eden has entered into a conditional Subscription Agreement with Sipcam, one of its commercial partners, pursuant to which Sipcam will subscribe for 16,666,500 new Ordinary Shares conditional on passing the resolutions at the General Meeting and Second Admission. The Issue Price of 6 pence per share equates to a discount of 23.8 per cent. to the closing price of 7.88 pence on 27 February 2020, the latest Business Day prior to publication of this announcement.

The Placing Shares and Subscription Shares will represent approximately 44 per cent. of the Enlarged Share Capital (on the assumption that the maximum number of Placing Shares and Subscription Shares are issued pursuant to the Placing and Subscription and that the Open Offer is fully subscribed). The New Ordinary Shares will, following each of the First Admission and the Second Admission, rank in full for all dividends and distributions declared, made or paid in respect of the issued Ordinary Share capital of the Company after the date of their respective issue and will otherwise rank equally in all other respects with the Existing Ordinary Shares.

The Placing and Open Offer Agreement

Pursuant to the terms of the Placing and Open Offer Agreement, Cenkos Securities has conditionally agreed to use its reasonable endeavours, as agent for the Company, to place the Placing Shares with certain institutional and other investors. The Placing, the Subscription and the Open Offer have not been underwritten.

The Placing and Open Offer Agreement is conditional upon, inter alia:

   --       Resolutions 1 and 2 being passed without amendment at the General Meeting; 

-- compliance by the Company in all material respects with its obligations under the Placing Agreement; and

-- with respect to the issue of the General Placing Shares only, Second Admission becoming effective by not later than 8.00 a.m. on 20 March 2020 (or such later date as is agreed between the Company and Cenkos, being not later than 8.00 a.m. on the Long Stop Date).

The Placing and Open Offer Agreement contains warranties from the Company in favour of Cenkos Securities in relation to, inter alia, the accuracy of the information in this announcement and other matters relating to the Group and its business. In addition, the Company has agreed to indemnify Cenkos Securities in relation to certain liabilities it may incur in respect of the Fundraise. Cenkos has the right to terminate the Placing and Open Offer Agreement in certain circumstances prior to First Admission and/or Second Admission, in particular, in the event of a breach of the warranties given to Cenkos in the Placing and Open Offer Agreement, the failure of the Company to comply in any material respect with its obligations under the Placing and Open Offer Agreement, the occurrence of a force majeure event or a material adverse change affecting the condition, or the earnings, management business, affairs, solvency or prospects of the Group as a whole.

Details of the Open Offer

Eden is proposing to raise up to approximately GBP0.5 million (before expenses) pursuant to the Open Offer. The Issue Price per Open Offer Share equates to a discount of 23.9 per cent. to the closing price of 7.88 pence on 27 February 2020, the latest Business Day prior to publication of this announcement. All Qualifying Shareholders are being given the opportunity to participate in the Open Offer.

The Open Offer provides Qualifying Shareholders with the opportunity to apply to acquire Open Offer Shares at the Issue Price pro rata to their holdings of Existing Ordinary Shares as at the Record Date on the following basis:

1 Open Offer Share for every 25 Existing Ordinary Shares

Entitlements to apply to acquire Open Offer Shares will be rounded down to the nearest whole number and any fractional entitlement to Open Offer Shares will be disregarded in calculating the Basic Entitlement. Qualifying Shareholders who do not take up their Basic Entitlements in full will experience a dilution to their interests of approximately 43.86 per cent. following Second Admission (assuming full subscription under the Placing, Subscription and the Open Offer).

Qualifying Shareholders should note that the Open Offer Shares have neither been placed under the Placing subject to clawback under the Open Offer nor have they been underwritten, and that neither the Placing nor the Subscription is conditional upon the number of applications received under the Open Offer.

Further details of the Open Offer and the application process relating to the Open Offer are set out in the Circular.

General Meeting

The Directors do not currently have authority to allot all of the New Ordinary Shares and, accordingly, the Board is seeking the approval of Shareholders to allot the New Ordinary Shares at the General Meeting.

A notice convening the General Meeting, which is to be held at the offices of DAC Beachcroft LLP, 25 Walbrook, London EC4N 8AF at 11.00 a.m. on 18 March 2020, will be set out at the end of the Circular. At the General Meeting, the following Resolutions will be proposed:

-- Resolution 1, which is an ordinary resolution, to authorise the Directors to allot relevant securities for cash up to an aggregate nominal amount of GBP1,766,209 being equal to 176,620,907 New Ordinary Shares (i.e. the maximum number of New Ordinary Shares available under the Placing, Subscription and Open Offer); and

-- Resolution 2, which is conditional on the passing of Resolution 1 and is a special resolution, to authorise the Directors to allot 176,620,907 New Ordinary Shares for cash pursuant to the Placing, Subscription and Open Offer on a non-pre-emptive basis.

The authorities to be granted pursuant to the Resolutions will expire on whichever is the earlier of (a) the conclusion of the next Annual General Meeting of the Company; and (b) the date falling six months from the date of the passing of the Resolutions (unless renewed, varied or revoked by the Company prior to or on that date) and shall be in addition to the Directors' authorities to allot relevant securities and dis-apply statutory pre-emption rights granted at the Company's Annual General Meeting held on 14 May 2019.

For the purposes of section 571(6)(c) of the Act, the Directors determined the Issue Price after consideration of applicable market and other considerations and having taken appropriate professional advice.

Shareholders will find accompanying the Circular a Form of Proxy for use in connection with the General Meeting. The Form of Proxy should be completed and returned in accordance with the instructions thereon so as to be received by Link Asset Services, The Registry, 34 Beckenham Road, Beckenham, Kent, BR3 4TU, as soon as possible and in any event not later than two Business Days before the time of the General Meeting. Completion and return of the Form of Proxy will not prevent a Shareholder from attending and voting at the General Meeting.

Recommendation

The Directors believe the Placing, Subscription and the Open Offer and the passing of the Resolutions to be in the best interests of the Company and its Shareholders as a whole. Accordingly, the Directors unanimously recommend Shareholders to vote in favour of the Resolutions as they intend so to do in respect of their beneficial shareholdings amounting to 1,991,717 Ordinary Shares, representing approximately 1 per cent. of the existing issued ordinary share capital of the Company.

As the Placing and Subscription and Open Offer are conditional, inter alia, upon the passing by Shareholders of the Resolutions at the General Meeting, Shareholders should be aware that, if the Resolutions are not passed and First Admission and Second Admission do not take place, the proceeds of the Placing and Subscription will not be received by the Company. In addition, the Open Offer will not proceed. Whilst the Company has sufficient working capital on its current business plan to fund its operations for the next 12 months, it is expected to remain loss making in the near term as it funds the development and commercialisation of new products. If the proceeds of the Fundraising are not received, the Company would need to pursue additional or alternative funding sources in the next 12 months. There would be no certainty of the terms under which alternative financing would be made available or at all.

DEFINITIONS

 
 Act                                the Companies Act 2006 (as amended) 
 AIM                                the market of that name operated by the London 
                                     Stock Exchange 
 AIM Rules                          the AIM Rules for Companies published by the 
                                     London Stock Exchange from time to time 
 Application Form                   the application form relating to the Open Offer 
                                     which accompanies the Circular (in the case 
                                     of Qualifying Non-CREST Shareholders only) 
 Basic Entitlement                  the number of Open Offer Shares which Qualifying 
                                     Shareholders are entitled to subscribe for 
                                     at the Issue Price pro rata to their holding 
                                     of Existing Ordinary Shares pursuant to the 
                                     Open Offer as described in Part III of the 
                                     Circular 
 Business Day                       a day (other than a Saturday or Sunday) on 
                                     which commercial banks are open for general 
                                     business in London, England 
 Cenkos or Cenkos Securities        Cenkos Securities plc 
 certificated form or               an Ordinary Share recorded on a company's share 
  in                                 register as being 
 certificated form                  held in certificated form (namely, not in CREST) 
 Company or Eden                    Eden Research plc, a company incorporated and 
                                     registered in England and Wales under the Companies 
                                     Act 2006 with registered number 03071324 
 CREST                              the relevant system (as defined in the CREST 
                                     Regulations) in respect of which Euroclear 
                                     is the operator (as defined in those regulations) 
 CREST Manual                       the rules governing the operation of CREST, 
                                     consisting of the CREST Reference Manual, CREST 
                                     International Manual, CREST Central Counterparty 
                                     Service Manual, CREST Rules, Registrars Service 
                                     Standards, Settlement Discipline Rules, CREST 
                                     Courier and Sorting Services Manual, Daily 
                                     Timetable, CREST Application Procedures and 
                                     CREST Glossary of Terms (all as defined in 
                                     the CREST Glossary of Terms promulgated by 
                                     Euroclear on 15 July 1996 and as amended since) 
                                     as published by Euroclear 
 CREST member                       a person who has been admitted to CREST as 
                                     a system-member (as defined in the CREST Manual) 
 CREST member account               the identification code or number attached 
  ID                                 to a member account in CREST 
 CREST participant                  a person who is, in relation to CREST, a system-participant 
                                     (as defined in the CREST regulations) 
 CREST participant ID               shall have the meaning given in the CREST Manual 
                                     issued by Euroclear 
 CREST payment                      shall have the meaning given in the CREST Manual 
                                     issued by Euroclear 
 CREST Regulations                  the Uncertificated Securities Regulations 2001 
                                     (SI 2001/3755) (as amended) 
 CREST sponsor                      a CREST participant admitted to CREST as a 
                                     CREST sponsor 
 CREST sponsored member             a CREST member admitted to CREST as a sponsored 
                                     member 
 Dealing Day                        a day on which the London Stock Exchange is 
                                     open for business in London 
 Directors or Board                 the directors of the Company whose names are 
                                     set out in the Circular, or any duly authorised 
                                     committee thereof 
 EIS                                enterprise investment scheme 
 EIS/VCT Placing                    the Placing Shares to be issued under the Placing 
                                     and either (i) in respect of which EIS relief 
                                     is to be claimed; or (ii) constituting a qualifying 
                                     holding for VCT purposes 
 EIS/VCT Placing Shares             the 86,182,500 new Ordinary Shares to be issued 
                                     and allotted to the Placees pursuant to the 
                                     EIS/VCT Placing 
 Enlarged Share Capital             the entire issued share capital of the Company 
                                     following completion of the Placing, Subscription 
                                     and Open Offer following First Admission and 
                                     Second Admission 
 EU                                 the European Union 
 Euroclear                          Euroclear UK & Ireland Limited, the operator 
                                     of CREST 
 Excess Application Facility        to the extent that Basic Entitlements to Open 
                                     Offer Shares are not subscribed for by Qualifying 
                                     Shareholders in full, such Open Offer Shares 
                                     will be available to satisfy excess applications, 
                                     subject to a maximum of 8,287,573 Open Offer 
                                     Shares in aggregate, as described in Part III 
                                     of the Circular 
 Excess CREST Open Offer            in respect of each Qualifying CREST Shareholder 
  Entitlement                        who has taken up his Basic Entitlement in full, 
                                     the entitlement to apply for Open Offer Shares 
                                     in addition to his Basic Entitlement credited 
                                     to his stock account in CREST, pursuant to 
                                     the Excess Application Facility, which may 
                                     be subject to scaling back in accordance with 
                                     the provisions of the Circular 
 Excess Entitlements                the entitlement for Qualifying Shareholders 
                                     to apply to acquire any number of Open Offer 
                                     Shares subject to the limit on applications 
                                     under the Excess Application Facility, as described 
                                     in Part III of the Circular 
 Excess Shares                      Open Offer Shares applied for by Qualifying 
                                     Shareholders in accordance with the Excess 
                                     Application Facility 
 Ex-entitlement Date                the date on which the Existing Ordinary Shares 
                                     are marked "ex" for entitlement under the Open 
                                     Offer, being 2 March 2020 
 Existing Ordinary Shares           the 207,189,337 Ordinary Shares in issue at 
                                     the date of this announcement, all of which 
                                     are admitted to trading on AIM 
 FCA                                the UK Financial Conduct Authority 
 FDA                                the US Food and Drug Administration 
 First Admission                    the admission to trading on AIM of the EIS/VCT 
                                     Placing Shares 
 Form of Proxy                      the form of proxy for use in connection with 
                                     the General Meeting which accompanies the Circular 
 FSMA                               the Financial Services and Markets Act 2000 
                                     (as amended) 
 Fundraise                          the Placing, Subscription and the Open Offer 
 General Meeting                    the general meeting of the Company to be held 
                                     at the offices of DAC Beachcroft LLP, 25 Walbrook, 
                                     London EC4N 8AF at 11.00 a.m. on 18 March 2020 
                                     (or any adjournment of that general meeting), 
                                     notice of which is set out at the end of the 
                                     Circular 
 General Placing                    the General Placing Shares to be issued under 
                                     the Placing other than (i) in respect of which 
                                     EIS relief is to be claimed; or (ii) constituting 
                                     a qualifying holding for VCT purposes 
 General Placing Shares             the 65,484,334 New Ordinary Shares to be issued 
                                     and allotted to the Placees pursuant to the 
                                     General Placing and which do not constitute 
                                     EIS/VCT Shares 
 Group                              the Company and its subsidiaries 
 HMRC                               Her Majesty's Revenue and Customs (which shall 
                                     include its predecessors, the Inland Revenue 
                                     and HM Customs and Excise) 
 ISIN                               International Securities Identification Number 
 Issue Price                        6 pence per Placing Share, Subscription Share 
                                     and per Open Offer Share 
 Link Asset Services                a trading name of Link Market Services Limited 
  or Link 
 London Stock Exchange              London Stock Exchange plc 
 Long Stop Date                     2 April 2020 
 Money Laundering Regulations       The Money Laundering, Terrorist Financing and 
                                     Transfer of Funds (Information on the Payer) 
                                     Regulations 2017, the Criminal Justice Act 
                                     1993 and the Proceeds of Crime Act 2002 
 New Ordinary Shares                together, the Placing Shares, the Subscription 
                                     Shares and the Open Offer Shares 
 Notice of General Meeting          the notice convening the General Meeting which 
                                     is set out at the end of the Circular 
 Open Offer                         the conditional invitation made to Qualifying 
                                     Shareholders to apply to subscribe for the 
                                     Open Offer Shares at the Issue Price on the 
                                     terms and subject to the conditions set out 
                                     in Part III of the Circular and, where relevant, 
                                     in the Application Form 
 Open Offer Entitlement             the entitlement of Qualifying Shareholders 
                                     to subscribe for Open Offer Shares allocated 
                                     to Qualifying Shareholders on the Record Date 
                                     pursuant to the Open Offer 
 Open Offer Shares                  up to 8,287,573 new Ordinary Shares being made 
                                     available to Qualifying Shareholders pursuant 
                                     to the Open Offer 
 Ordinary Shares                    ordinary shares of GBP0.01 each in the capital 
                                     of the Company 
 Overseas Shareholders              a Shareholder with a registered address outside 
                                     the United Kingdom 
 Placee                             the subscribers for the Placing Shares pursuant 
                                     to the Placing 
 Placing                            the EIS/VCT Placing and General Placing 
 Placing Shares                     the EIS/VCT Placing Shares and the General 
                                     Placing Shares 
 Prospectus Regulation              the EU Prospectus Regulation (Regulation (EU) 
                                     2017/1129) in relation to offers of securities 
                                     to the public and the admission of securities 
                                     to trading on a regulated market 
 Qualifying CREST Shareholders      Qualifying Shareholders holding Existing Ordinary 
                                     Shares in a CREST account 
 Qualifying Non-CREST               Qualifying Shareholders holding Existing Ordinary 
  Shareholders                       Shares in certificated form 
 
 Qualifying Shareholders            holders of Existing Ordinary Shares on the 
                                     register of members of the Company at the Record 
                                     Date (but excluding any Overseas Shareholder 
                                     who has a registered address in the United 
                                     States or any other Restricted Jurisdiction) 
 Receiving Agents                   Link Asset Services 
 Record Date                        6.00 p.m. on 27 February 2020 in respect of 
                                     the entitlements of Qualifying Shareholders 
                                     under the Open Offer 
 Regulatory Information             has the meaning given in the AIM Rules for 
  Service                            Companies 
 Resolutions                        the resolutions set out in the Notice of General 
                                     Meeting 
 Restricted Jurisdiction            each and any of Australia, Canada, Japan, New 
                                     Zealand, the Republic of South Africa or the 
                                     United States and any other jurisdiction where 
                                     the Offer would breach any applicable law or 
                                     regulations 
 Second Admission                   the admission to trading on AIM of the General 
                                     Placing Shares 
 Shareholders                       holders of Ordinary Shares 
 Sipcam                             S.I.P.C.A.M. Societa Italiana Prodotti Chimici 
                                     per l'Agricoltura Milano S.P.A. 
 Subscription                       the Subscription by Sipcam for the Subscription 
                                     Shares 
 Subscription Shares                the 16,666,500 new Ordinary Shares to be subscribed 
                                     pursuant to the Subscription 
 UK or United Kingdom               the United Kingdom of Great Britain and Northern 
                                     Ireland 
 Uncertificated or Uncertificated   recorded on the relevant register or other 
  form                               record of the shares or other security concerned 
                                     as being held in uncertificated form in CREST, 
                                     and title to which, by virtue of the CREST 
                                     Regulations, may be transferred by means of 
                                     CREST 
 US Person                          has the meaning given in the United States 
                                     Securities Act 1933 (as amended) 
 VCT                                Venture Capital Trust 
 voting rights                      means all voting rights attributable to the 
                                     share capital of the Company which are currently 
                                     exercisable at a general meeting 
 GBP and p                          United Kingdom pounds sterling and pence respectively, 
                                     the lawful currency of the United Kingdom 
 

EXPECTED TIMETABLE OF PRINCIPAL EVENTS

 
 Record Date for the Open Offer                           6.00 p.m. on     27 February 
                                                                                  2020 
 Announcement of the Placing, Subscription                                 28 February 
  and the Open Offer,                                                             2020 
 Publication and posting of the Circular,                                 2 March 2020 
  Form of Proxy and to Qualifying Non-CREST 
  shareholders only, the Application Form 
 Existing Ordinary Shares marked "ex"                     8.00 a.m. on    2 March 2020 
  by the London Stock Exchange 
 Open Offer Entitlements and Excess Open                                  3 March 2020 
  Offer Entitlements credited to stock 
  accounts in CREST of Qualifying CREST 
  Shareholders 
 Recommended latest time and date for                     4.30 p.m. on   11 March 2020 
  requesting withdrawal of Open Offer Entitlements 
  from CREST 
 Latest time and date for depositing Open                 3.00 p.m. on   12 March 2020 
  Offer Entitlements and Excess CREST Open 
  Offer Entitlements in CREST 
 Latest time and date for splitting Application           3.00 p.m. on   13 March 2020 
  Forms (to satisfy bona fide market claims 
  only) 
 Latest time and date for receipt of completed              11.00 a.m.   16 March 2020 
  Forms of Proxy                                                    on 
 Record time and date for entitlement                Close of business   16 March 2020 
  to vote at the General Meeting                                    on 
 Latest time and date for receipt of completed              11.00 a.m.   17 March 2020 
  Application Forms and payment in full                             on 
  under the Open Offer or settlement of 
  relevant CREST instruction (as appropriate) 
 General Meeting                                            11.00 a.m.   18 March 2020 
                                                                    on 
 Announcement of result of General Meeting                               18 March 2020 
  and the Open Offer 
 First Admission and commencement of dealings             8.00 a.m. on   19 March 2020 
  in the EIS/VCT Shares on AIM 
 Second Admission and commencement of                     8.00 a.m. on   20 March 2020 
  dealings in the General Placing Shares, 
  the Subscription Shares and the Open 
  Offer Shares on AIM 
 New Ordinary Shares credited to CREST                                   19 March 2020 
  members' accounts in respect of the EIS/VCT 
  Shares 
 New Ordinary Shares credited to CREST                                   20 March 2020 
  members' accounts in respect of General 
  Placing Shares, the Subscription Shares 
  and the Open Offer Shares 
 Despatch of definitive share certificates                          by   26 March 2020 
  in certificated form 
 

APPIX

 
 Mevalone ä Regulatory Approval Log 
     Mevalone           Registration               Crops              Regulatory        Estimated       Distributor 
  ä Territory         Details                                      position        Market size 
                                                                                          (EURm) 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 France              Apples,               Apples                   Emergency         0.5              Sumi Agro 
                      storage                                        use approval 
                      diseases 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 France              Botrytis              Table grapes,            Approved          51.7             Sumi Agro 
                      in field              Wine Grapes 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Malta               Botrytis              Table Grape,             Approved          <0.5             Sipcam 
                      in field              Wine grape 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Bulgaria            Botrytis              Table Grape,             Approved          1.1              KNE Certis 
                      in Field              Wine grape 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Cyprus              Botrytis              Table Grape,             Approved          <0.5             KNE / Coststas 
                      in field              Wine grape                                                  Christodoulou 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Cyprus              Minor Use             Aubergine,               Approved          <0.5             KNE / Coststas 
                      - Botrytis            Kiwi, Pomegranate,                                          Christodoulou 
                      in field              Spring onion 
                      and glasshouse 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Portugal            Botrytis              Table Grape,             Approved          1.2              Sipcam 
                      in field              Wine grape 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Italy               Botrytis              Table grape              Approved          30.5             Sipcam 
                      in open               and Wine 
                      field                 grape 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Italy               Emergency             Kiwi                     Emergency         <0.5             Sipcam 
                      Use Authorisations                             authorization 
                      - botrytis                                     period from 
                      in field                                       18 June 2019 
                                                                     to 15 October 
                                                                     2019 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Italy               Emergency             STRAWBERRY               Emergency         19.5             Sipcam 
                      Use Authorisations    AND SMALL                authorization 
                      - botrytis            FRUITS (blackberries,    period from 
                      in field              wild blackberries,       8 April 2019 
                      and glasshouse        raspberries,             to 5 August 
                                            blueberries,             2019 (2) 
                                            American 
                                            giant blueberries, 
                                            currants, 
                                            gooseberries, 
                                            rose hips, 
                                            mulberries, 
                                            blueberries, 
                                            elderberries, 
                                            other berries) 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Italy               Emergency             Pomegranate              Emergency         <0.5             Sipcam 
                      Use Authorisations                             authorization 
                      - botrytis                                     period from 
                      in field                                       8 April 2019 
                                                                     to 5 August 
                                                                     2019 (2) 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Kenya               Botrytis              Squash, French           Approved          <0.5             Lachlan 
                      in field              Beans 
                      and glasshouse 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Kenya               Powdery               Roses, Snow              Approved          2.8              Lachlan 
                      mildew and            Peas 
                      botrytis 
                      in field 
                      and glasshouse 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Spain               Botrytis              Table grape              Approved          14.0             Sipcam 
                      and control           and wine 
                      of powdery            grapes 
                      mildew 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Greece,             Botrytis              Table grapes,            Approved          3.7              Efthymiadis 
  Balkans             in field              wine grapes 
                      and glasshouse 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Greece,             Minor Use             Aubergines,              Approved          5.4              Efthymiadis 
  Balkans             - Botrytis            kiwis, pomegranates 
                      in field              and spring 
                      and glasshouse        onions. 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 FYROM               Botrytis              Table grapes,            Approved          <0.5             Efthymiadis 
                      in field              wine grapes 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 FYROM               Minor Use             Aubergines,              Approved          <0.5             Efthymiadis 
                      - Botrytis            kiwis, pomegranates 
                      in field              and spring 
                      and glasshouse        onions. 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Albania             Botrytis              Table grapes,            Approved          <0.5             Efthymiadis 
                      in field              wine grapes 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Albania             Minor Use             Aubergines,              Approved          <0.5             Efthymiadis 
                      - Botrytis            kiwis, pomegranates 
                      in field              and spring 
                      and glasshouse        onions. 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Australia           Botrytis              Grapes                   Submitted         <0.5             Sipcam 
                      in field 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 New Zealand         Botrytis              Grapes                   TBC               6.9              Sipcam 
                      in field 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 United States       Botrytis              Grapes                   Submitted         12.6             Eastman 
                      in field                                       to EPA 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Benelux             Botrytis              Grapes                   Dossier being     Grape <0.5       Sipcam 
                      in field                                       finalised         Other crops 
                                                                     for submission    - 4.9 
                                                                     in 2020 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Germany             Fungicide             Grapes and               Dossier being     Grape Botrytis   SumiAgro 
  and Poland          for grapes            Apples                   finalised         - 14.0 
  and three           and treatment                                  for submission    Apples - 
  other central       of storage                                     in 2020           0.1 
  European            diseases 
  markets             on apples 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Serbia              Botrytis              Table grape              Submitted         <0.5             KNE Certis 
                      in field              and wine                 2019 
                                            grapes 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 Romania             Botrytis              Table grape              Submitted         1.3              KNE Certis 
                      in field              and wine                 2019 
                                            grapes 
                    --------------------  -----------------------  ----------------  ---------------  --------------- 
 
 
                                     Cedroz ä Regulatory Approval Log 
   Cedroz        Registration                 Crops                  Regulatory       Estimated     Distributor 
    ä          details                                            position         Market 
  Territory                                                                           size (EURm) 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Malta         Nematodes in       cucurbitaceous                   Approved          <0.5           Eastman 
                open fields and    (cucumbers, 
                glasshouse for     courgettes, 
                wide range of      melons, pumpkins, 
                crops              watermelons), 
                                   fruiting vegetables 
                                   (aubergine, 
                                   pepper, sweet 
                                   pepper, chili, 
                                   pepino), strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Mexico        Nematodes in       Tomatoes, potato,                Approved          4.8            Eastman 
                open fields and    pepper, eggplant, 
                glasshouse for     melon, watermelon, 
                wide range of      cucumber, pumpkin, 
                crops              chayote squash 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Belgium       Nematodes in       strawberries                     Approved          <0.5           Eastman 
                greenhouses for    (production 
                wide range of      field), strawberries 
                crops              (selection 
                                   and multiplication 
                                   field), tomatoes, 
                                   bell pepper, 
                                   Spanish pepper, 
                                   aubergine/eggplant 
                                   and pepino, 
                                   cucumber, courgette/patisson, 
                                   melon, pumpkin 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Italy         Nematodes open     tomato, peppers,                 Emergency         30.6           Eastman 
                field and in       eggplant, chili,                 Approval 
                greenhouses        melon, watermelon, 
                                   pumpkin, cucumber, 
                                   courgette, 
                                   strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Spain         Nematodes open     tomato, peppers,                 Submitted         14.4           Eastman 
                fields and in      eggplant, chili,                 and Pending 
                greenhouses        melon, watermelon, 
                                   pumpkin, cucumber, 
                                   courgette, 
                                   strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 USA           Nematodes open     Fruiting Vegetables:             Submitted         83.0           Eastman 
                fields and in      Eggplant, Okra,                  and Pending 
                greenhouses        Pepper, Tomato 
                                   Cucurbit 
                                   Vegetables: 
                                   Cantaloupe, 
                                   Cucumber, Muskmelon, 
                                   Pumpkin, Squash, 
                                   Watermelon, 
                                   Zucchini 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 United        Nematodes in       tomato, (sweet)                  Submitted         <0.5           Eastman 
  Kingdom       greenhouses.       peppers, eggplant,               and Pending 
                                   chili, pepino, 
                                   melon, pumpkin, 
                                   cucumber, courgette, 
                                   strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Netherlands   Nematodes in       strawberries,                    Submitted         0.6            Eastman 
                greenhouses.       Cucurbitaceae                    and pending 
                                   (edible peel),                   (decision 
                                   Cucurbitaceae                    expected 
                                   (not edible                      imminently) 
                                   peel), Solanaceae 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 France        Nematodes in       tomato, peppers,                 Submitted         5.0            Eastman 
                greenhouses        eggplant, chili,                 and Pending 
                                   melon, pumpkin, 
                                   cucumber, courgette, 
                                   strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Greece        Nematodes open     tomato, peppers,                 Dossier           3.2            Eastman 
                fields and in      eggplant, chili,                 prepared 
                greenhouses        melon, watermelon, 
                                   pumpkin, cucumber, 
                                   courgette, 
                                   strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Portugal      Nematodes open     tomato, peppers,                 Dossier           1.9            Eastman 
                fields and in      eggplant, chili,                 submitted 
                greenhouses        melon, watermelon,               and pending 
                                   pumpkin, cucumber, 
                                   courgette, 
                                   strawberries 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Morocco       Nematodes open     tomato, peppers,                 In progress       6.3            Eastman 
                fields and in      eggplant, chili, 
                greenhouses        melon, watermelon, 
                                   pumpkin, cucumber, 
                                   courgette, 
                                   strawberries, 
                                   (raspberry 
                                   and green bean) 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Costa Rica    Nematodes open     tomato, melon,                   Trials            0.4            Eastman 
                fields             potato, peppers                  done. Dossier 
                                                                    being prepared 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Guatemala,    Nematodes open     tomato, melon,                   In progress       0.9            Eastman 
                fields             potato, peppers 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Honduras      Nematodes open     tomato, melon,                   In progress       <0.5           Eastman 
                fields             potato, peppers 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 Israel        Nematodes open     Multiple, TBC                    In progress       TBC            Eastman 
                fields 
              -----------------  -------------------------------  ----------------  -------------  ------------ 
 

The information contained within this announcement (the "Announcement") is deemed by the Company to constitute inside information as stipulated under the Market Abuse Regulations (EU) No. 596/2014. Upon the publication of this Announcement via Regulatory Information Service, this inside information is now considered to be in the public domain.

For further information contact:

 
 Eden Research plc                                www.edenresearch.com 
 Sean Smith 
  Alex Abrey                                      01285 359 555 
 
 
   Cenkos Securities (Nominated advisor and 
   broker) 
 Giles Balleny / Cameron MacRitchie (corporate 
  finance) 
  Michael Johnson (sales)                         020 7397 8900 
 
 
   Hawthorn Advisors (Financial PR) 
 Lorna Cobbett                                    eden@hawthornadvisors.com 
  Jana Tsiligiannis 
 

Notes:

Eden Research is an AIM quoted company that develops and supplies breakthrough biopesticide products and natural microencapsulation technologies to the global crop protection, animal health and consumer products industries

Eden's Sustaine encapsulation technology harnesses the biocidal efficacy of naturally occurring chemicals produced by plants (terpenes) and can be used with both natural and synthetic compounds to enhance their performance and ease-of-use.

Sustaine microcapsules are naturally derived, plastic-free, biodegradable micro-spheres derived from yeast extract. They produce stabilised aqueous suspensions which, are easy to mix and apply, have phased release patterns, are safer for the environment and the crops themselves.

The European Chemicals Agency (ECHA) has proposed an EU-wide restriction on the placing on the market or use of "intentionally-added" microplastic particles. The proposed restriction includes the use of microplastics for agricultural and horticultural purposes, including polymers utilized for controlled-release fertilizers, encapsulated plant protection products (PPPs), seed coatings, and biocides.

By 2025 in the EU, pesticides containing synthetic polymer microplastics are likely to be banned and removed from the market. The only acceptable alternative is the substitution with biodegradable formulations. Reformulated products will need to be evaluated and registered within the five-year transition period.

Sustaine is one of the only viable, proven and immediately registerable solutions to the microplastics problem in formulations requiring encapsulation.

Historically, terpenes have had limited commercial use in the agrochemical sector due to their volatility, phytotoxicity and poor solubility. Sustaine provides a unique, environmentally friendly solution to these problems and enables terpenes to be used as effective, low-risk agrochemicals.

Eden is developing these technologies through innovative research and a series of commercial production, marketing and distribution partnerships.

The Company has a number of patents and a pipeline of products at differing stages of development targeting specific areas of the global agrochemicals industry. To date, the Company has invested in the region of GBP14m in developing and protecting its intellectual property and seeking regulatory approval for products that rely upon the Company's technologies. Revenues earned by the Company have been modest whilst the Company has concentrated on securing patent protection for its intellectual property, gaining regulatory approvals, identifying suitable industrial partners, and entering into commercial agreements.

In May 2013, the three actives that comprise Eden's first commercial product, Mevalone, were approved as new ingredients for use in plant protection products by the European Commission ("EC"). This represented a major milestone in the commercialisation of Eden's technology and is a significant accomplishment for any company. To illustrate this point, one should note that in 2013, Eden's approvals represented 3 of only 10 new active ingredients approved by the EC.

Mevalone is a foliar fungicide which has been authorised for sale in Kenya, Malta, Greece, Bulgaria,

Spain, Italy, France, Cyprus, Albania, Portugal and Macedonia.

Cedroz is a nematicide which has been authorised for sale in Malta, Belgium and Mexico.

Eden was admitted to trading on AIM on 11 May 2012 and trades under the symbol EDEN.

This information is provided by RNS, the news service of the London Stock Exchange. RNS is approved by the Financial Conduct Authority to act as a Primary Information Provider in the United Kingdom. Terms and conditions relating to the use and distribution of this information may apply. For further information, please contact rns@lseg.com or visit www.rns.com.

END

IOESESFDAESSEDE

(END) Dow Jones Newswires

February 28, 2020 08:35 ET (13:35 GMT)

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