RNS Number:2958N
Skyepharma PLC
08 July 2003

8 July 2003



                                 SkyePharma PLC

Application has been made to the London Stock Exchange and to the UK Listing
Authority for the admission of 3,820,231 ordinary shares of 10p each, ranking
pari passu with the current issued share capital, to the Official List. These
shares have been allotted in connection with the following:-

1. 3,690,211 Ordinary Shares in aggregate have been allotted by way of deferred
consideration in connection with the agreement for the acquisition by the
Company of RTP Pharma Inc.. In consideration for the loss of certain option
rights by shareholders of RTP Pharma Inc., the Company was required to issue
200,000 additional shares, or pay an amount in cash, for each penny difference
between the actual share price at 30 June 2003, as calculated in accordance with
the terms of the agreement, and 82 pence. The Company has chosen to issue the
additional shares. This fulfils the Company's obligation.

2. 130,020 ordinary shares in aggregate have also been allotted in connection
with the exercise of Employee Share Options as follows:-

13 June 2003          113,395 ordinary shares

19 June 2003       10,125 ordinary shares

26 June 2003          6,500 ordinary shares

It is anticipated that these shares will be listed on the Official List of the
UK Listing Authority and traded on the London Stock Exchange PLC on Thursday
10th July 2003.




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