leifsmith
1 month ago
This Morning: TNF Pharmaceuticals Prepares to Advance Lead Clinical Program Targeting Age-Related Decline
MYMD-1® development to continue through fully funded mid-stage clinical trials
Clinical study of MYMD-1 in sarcopenia/frailty met primary endpoints for significantly reducing chronic inflammatory markers with statistical significance
MYMD-1 shown to inhibit excessive activity of TNF-alpha to regulate the immuno-metabolic system
Company holds FDA-cleared Phase 2 INDs for MYMD-1 in two additional chronic inflammatory conditions, rheumatoid arthritis and Hashimoto’s thyroiditis
Press Release here: https://www.businesswire.com/news/home/20240821460281/en/
"Prepares to advance" — this statement tells us nothing, and the content of the release adds nothing to what is already known.
The new president, Dr. Glass, is quoted as saying, "Our next steps, to be revealed soon, will extend our reach toward significant and sustainable value creation, and long-term Company growth.” <-- If this "to be revealed soon" news is substantial it will prove that today's release was not just an attempt to boost the stock price.
As has been said by critical_perspective we have good reason for skepticism. Today's pre-market action shows that there are some who are taking this release as an opportunity to get out. I hope they will be proven to have misjudged the new management. The science is real and good. What's needed is action. We may be past the point where promises of action will inspire anything.
critical_perspective
1 month ago
Sorry, Leif, my last post was supposed to be a reply to yours. I also wanted to add that, yes, the reported dramatic improvement in those two dogs is absolutely impressive. Phenomenal, actually! (hopefully it is true). However I still have serious reservations about the company's ownership & leadership. Time will tell.
leifsmith
5 months ago
From the 8-K just filed: https://ir.mymd.com/sec-filings/all-sec-filings##document-1028-0001493152-24-013870-1
Bio of Dr. Mitchell Glass (from https://www.medproinvestors.com/team; out of date probably)
Dr. Mitchell Glass is a 25 year veteran of the pharmaceutical industry.
His experience includes senior positions at top ten pharmaceutical companies,
as well as investment in and management of start-ups and biotechs.
After seven years of research, teaching and patient care at the University of Pennsylvania, Dr. Glass joined ICI Pharmaceuticals in 1988 where he established the pulmonary therapeutics group and led the development and submission of the antileukotriene ACCOLATE®. From 1995 to 1996, Dr. Glass was Vice President and Director at SmithKline Beecham where he was responsible for cardiovascular, respiratory, renal and metabolic drug development and commercialization, including submission of the NDA/MAA for COREG®. From 1998 to 2003, Dr. Glass was Chief Medical Officer and VP of Clinical Development and Regulatory Affairs of AtheroGenics Inc. (AGIX), where he led product development from IND to initiation of Phase 3 for AGI1067 and was a member of the IPO team. Dr. Glass later joined AQUMEN Biopharmaceuticals KK and NA as CEO of AQUMEN NA and currently serves as Executive VP R&D and Chief Medical Officer of Invion Limited. Dr. Glass graduated from the University of Chicago and is board certified in internal medicine, pulmonary and critical care medicine.
***
I have no idea what any of this 8-K signifies. Maybe tells us some preferred stock can be converted to common on terms specified in subsidiary documents.
critical_perspective
6 months ago
The primary target for Telomir -- age reversal -- just so happens to align with MYMD's primary target of sarcopenia. Coincidence? I haven't been able to see the actual makeup of Telomir-1 but, like you, I suspect its development is directly linked to the research done for MYMD-1. Why haven't the full results from the sarcopenia study (which ended early June 2023) been published yet? The Annual Report just came out the other day and it does not inspire confidence. Actually, from what I can make of it, it looks quite disappointing... especially with the departure of key individuals. In addition, the lack of communication from the company is disturbing, and in light of everything else, rather alarming.
For those of us who were invested in Williams' previous ventures (i.e. Star Scientific, Rock Creek), this behavior of questionable actions (to say the least) unfortunately appears to be his M.O. He found a compelling means of raising significant capital and then leaving investors dry. I don't have a good feeling about any of it. It is indeed very unfortunate, because the product(s) and the research behind them were truly promising and significant!
SeanVan
7 months ago
I have been telling in this board to all since many months that.... The Chairman of the Board Josh Silverman came from AKERS who is expert inn manipulation of the stocks... Now 30:1 reverse split will happen tomorrow, which reduces to shares 2,091,638. Important to note that, they already got approval from NASDAQ to add upto 16M new stocks if needed. This so called manipulators MyMD Founder Johnnie W, & Silverman add those remaining shares in short time which dilutes the value by saying Phase 3 purposes. This company is living on all frauds. What do you say?
leifsmith
8 months ago
Canadian patent 3013634 granted
Abstract: "In one aspect, a method of increasing hair growth includes administering to an individual in need thereof a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable vehicle therefor. In another aspect, a method of improving the appearance of hair includes administering to an individual in need thereof a pharmaceutical composition containing a therapeutically effective amount of isomyosmine or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable vehicle therefor."
isomyosmine (MYMD-1) is interestingly versatile.
Near the close the price went as high as 0.21 on over 3,200,000 shares, then collapsed to 0.17 on much lower volume, closing at 0.203. After hours 0.18 seems to be popular. Hair raising, if you care. I don't much. This announcement means little, far as I can tell.