Funds, and thus Baker Bros. Advisors LP has complete and unlimited discretion and authority with respect to the Baker Funds’ investments and voting power over investments. According to an amended Schedule 13D filed March 15, 2023 and Form 4 filed April 4, 2023, the total number of shares of our common stock beneficially owned includes shares directly held as follows:
Holder
|
|
|
Shares
|
|
667, L.P.
|
|
|
|
|
2,734,189 |
|
|
Baker Brothers Life Sciences, L.P.
|
|
|
|
|
33,212,097 |
|
|
Julian C. Baker
|
|
|
|
|
510,031 |
|
|
Felix J. Baker
|
|
|
|
|
281,190 |
|
|
Entities affiliated with Julian C. Baker and Felix J. Baker
|
|
|
|
|
79,305 |
|
|
Pursuant to an agreement between Baker Bros. Advisors LP and Julian C. Baker, Baker Bros. Advisors LP has sole voting and dispositive power with respect to 229,114 shares owned directly by Julian C. Baker that were received by Mr. Baker upon exercise of options, upon vesting of RSUs or in lieu of cash fees in connection with serving as a member of our Board of Directors and with respect to 117,264 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023 that are held by Julian C. Baker and that are included in the number of shares shown as beneficially owned.
(3)
According to an amended Schedule 13G filed February 9, 2023, filed by The Vanguard Group (“Vanguard”), Vanguard, in its capacity as investment adviser, may be deemed to beneficially own all shares listed in the table, and has sole dispositive power with respect to 20,752,117 shares, shared dispositive power with respect to 781,701 shares, and shared voting power with respect to 277,492 shares. The address of the principal place of business of Vanguard is 100 Vanguard Blvd., Malvern, Pennsylvania 19355.
(4)
According to an amended Schedule 13G filed January 25, 2023, filed by BlackRock, Inc. (“BlackRock”), BlackRock, in its capacity as investment adviser, may be deemed to beneficially own and has sole dispositive power with respect to all shares listed in the table and has sole voting power with respect to 18,303,077 shares. The address of the principal place of business of BlackRock is 55 East 52nd Street, New York, New York, 10022.
(5)
According to an amended Schedule 13G filed February 14, 2023, filed by Dodge & Cox, in its capacity as investment adviser, may be deemed to beneficially own and has sole dispositive power with respect to all shares listed in the table and has sole voting power with respect to 18,209,985 shares. The address of the principal place of business of Dodge & Cox is 555 California Street, 40th Floor, San Francisco, California 94104.
(6)
Includes 938,784 shares subject to RSUs and earned performance shares that will vest and options exercisable within 60 days of April 18, 2023.
(7)
Includes 134,350 shares subject to RSUs and earned performance shares that will vest and options exercisable within 60 days of April 18, 2023.
(8)
Includes 174,665 shares subject to RSUs and earned performance shares that will vest and options exercisable within 60 days of April 18, 2023.
(9)
Includes 41,428 shares subject to RSUs and earned performance shares that will vest and options exercisable within 60 days of April 18, 2023.
(10)
Includes 198,440 shares subject to RSUs and earned performance shares that will vest and options exercisable within 60 days of April 18, 2023.
(11)
Includes 132,264 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(12)
Includes 17,178 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(13)
Includes 132,264 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(14)
Includes 91,014 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(15)
Includes 74,152 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(16)
Includes 31,077 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(17)
Includes 8,376 shares subject to RSUs that will vest and options exercisable within 60 days of April 18, 2023.
(18)
Includes shares pursuant to the second paragraph of note (2) and notes (6), (7), (8), (9), (10), (11), (12), (13), (14), (15), (16), and (17) above, and 472,238 shares subject to RSUs and earned performance shares that will vest and options exercisable within 60 days of April 18, 2023 held by other executive officers of the Company.