FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

DeLong Mark Jeffrey
2. Date of Event Requiring Statement (MM/DD/YYYY)
3/30/2021 

3. Issuer Name and Ticker or Trading Symbol

Apellis Pharmaceuticals, Inc. [APLS]
(Last)        (First)        (Middle)

C/O APELLIS PHARMACEUTICALS, INC., 100 FIFTH AVENUE, 3RD FLOOR
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          _____ 10% Owner
___X___ Officer (give title below)        _____ Other (specify below)
Senior Vice President /
(Street)

WALTHAM, MA 02451      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 8698 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)  (1)1/27/2031 Common Stock 30000 $44.90 D  
Stock Option (Right to Buy)  (1)2/9/2030 Common Stock 18750 $44.33 D  
Stock Option (Right to Buy)  (1)2/4/2028 Common Stock 50000 $15.52 D  
Stock Option (Right to Buy)  (1)2/27/2029 Common Stock 30000 $13.85 D  

Explanation of Responses:
(1) This stock option will vest as to 25% of the shares underlying the options on the first anniversary of the grant date, with the remaining 75% of the shares underlying the options vesting in equal monthly installments thereafter through the fourth anniversary of the grant, subject to continued service.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
DeLong Mark Jeffrey
C/O APELLIS PHARMACEUTICALS, INC.
100 FIFTH AVENUE, 3RD FLOOR
WALTHAM, MA 02451


Senior Vice President

Signatures
/s/ David Watson, attorney-in-fact for Mark Delong4/9/2021
**Signature of Reporting PersonDate

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