Therapeutic Solutions International Signs
Letter of Intent to License Adult Stem Cell
Therapy for Treatment of Chronic Traumatic Encephalopathy
to WCTE, Inc., a Wes Chandler
Company
Company Started by NFL Star Aims
to Cure Devastating Concussion Associated Condition using
Regenerative Medicine
OCEANSIDE, CA --
December 16, 2019 -- InvestorsHub NewsWire
-- Therapeutic Solutions
International, Inc., (OTC
Markets:
TSOI)
announces today the
signing
of a Letter of Intent
to license exclusive
rights to a patented [1] adult stem cell for treatment of
chronic
traumatic encephalopathy (CTE) and traumatic brain injury
(TBI) within the field of
sports and athletics.
The stem
cell
is
unique in
that it possesses features of mesenchymal stem cells, however, it
outperforms mesenchymal
cells in
terms of a) enhanced growth factor production; b) augmented ability
to secrete exosomes; and c) superior angiogenic and neurogenic
ability [2].
Chronic Traumatic
Encephalopathy (CTE) is caused by repetitive
concussive/sub-concussive hits to the head sustained over a period
of years and is often found in football players. The condition is
characterized by memory loss, impulsive/erratic behavior, impaired
judgment, aggression, depression, and dementia. In many patients
with CTE, it is anatomically characterized by brain atrophy,
reduced mass of frontal and temporal cortices, and medial temporal
lobe.
"Back in the summer of
2018 Wes Chandler introduced myself and our team to the terrible
condition known as CTE and we have worked with Wes and his team
ever since on numerous levels to develop a strategy for combatting
CTE and Traumatic Brain Injury (TBI)" said Timothy Dixon,
President, and CEO of TSOI. "Many of our recent
developments within the field of CTE and TBI was a direct result of
the leadership provided by Wes so we could fully appreciate the
devastation this injury causes and develop our products to that
end. We are honored deeply today to engage with Wes Chandler on
this timely and mission-critical program."
"The advantage of the
stem cell we are licensing is that it has already been utilized in
clinical trials intravenously and possesses an excellent safety
record,"
said
Wes
Chandler,
CEO of WCTE, Inc.
"Through
working with our team of internationally renowned scientists, we
are confident in filing an Investigational New Drug (IND)
application with the FDA for Chronic Traumatic Encephalopathy
within the First Quarter of 2020 This will position us to
provide not just prophylactic approaches to this terrible
condition, but begin the process of developing a treatment that has
a shot of actually reversing brain damage."
In a recent article
published by Alexi Cohen in the Boston Harold titled "CTE risk,
severity increases with years playing football, study shows" Ms.
Cohen
stated in
part that,
"The risk
and severity of developing the life-altering disease, chronic
traumatic encephalopathy, increases with the number of years
playing football according to
a new study that researchers say affirms a strong relationship
between football and CTE.
"We have sufficient
data now to say that we are very confident that this relationship
that we are finding is not due to chance, it's a clear
relationship," said Dr. Jesse Mez,
lead author on the study and director of the Boston University
Alzheimer's Disease Center. The risk of
developing CTE increased by 30% for each year of playing football,
the data out of the Boston University CTE Center showed.
Among those who
already had CTE, the odds of developing a severe form of the
disease increased by 14% for each additional year of football
played. The study examined
the brains of 223 deceased amateur and professional football
players with CTE and 43 without the disease. All of the samples
underwent a complete neuropathological evaluation.
Mez
said he
hopes the findings lead others to make "thoughtful decisions about
play" and understand the risks involved in tackle
football.
"I would not let my
kids play football given these results," said Mez.
Men who
played football for more than 14.5 years were 10 times more likely
to develop CTE than those who played fewer, according to the report
published in Annals of Neurology on October 7,
2019 [3].
About
Therapeutic Solutions International, Inc.
Therapeutic Solutions
International is focused on immune modulation for the treatment of
several specific diseases. Immune modulation refers to the ability
to upregulate (make more active) or downregulate (make less active)
one's immune system. The Company's corporate website is at
www.therapeuticsolutionsint.com
and our
e-commerce is at www.youcanordernow.com and for additional
info on NanoStilbene visit www.mynanostilbene.com.
About
WCTE, Inc.
The
Company was formed because of the urgent unmet need to treat
amateur and professional athletes suffering from Chronic Traumatic
Encephalopathy, who have sacrificed their health and their lives
for popular entertainment. Now that they need our help, it is
our responsibility to be there for them. The Company has the vision
of identifying, integrating and incorporating the latest
technologies in order to provide a fighting chance for
patients.
These statements have
not been evaluated by the Food and Drug Administration. These
products are not intended to diagnose, treat, cure, or prevent any
disease.
[1] https://patents.google.com/patent/US9803176?oq=9803176
[2] https://www.ncbi.nlm.nih.gov/pubmed/23057960
[3]
https://onlinelibrary.wiley.com/doi/10.1002/ana.25611
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Harbor
Statement
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release contains forward-looking statements that are based upon
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