RNS Number:7234M
Profile Therapeutics PLC
24 June 2003


To Profile Therapeutics plc


Disclosure of Interest Notice - Companies Act 1985 Part VI

In compliance with Part VI of the above Act, we write to inform you of the new
aggregate shareholding in your company held by Britannic Investment Managers
Limited.

Following the disposal of 1,983,244 shares on 14th May 2003 we now have a 
holding of zero ordinary shares.  This represents a decrease in our notifiable
interest from 4.04% to 0% of the shares in issue.


From Britannic Asset Management


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