CAT Catco Reinsurance Opportunities Fund Limited

RNS Number:6919G
Cambridge Antibody Tech Group PLC
21 December 2004

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   Name of company

Cambridge Antibody Technology

2)   Name of shareholder having a major interest
AstraZeneca UK Limited


3)   Please state whether notification indicates that it is in respect of
     holding of the shareholder named in 2 above or in respect of a
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18
as in 2 above


4)   Name of the registered holder(s) and, if more than one holder, the
     number of shares held by each of them
as in 2 above


5)   Number of shares/amount of stock acquired
10,217,983


6)   Percentage of issued class
19.86%

7)   Number of shares/amount of stock disposed
None


8)   Percentage of issued class
N/A


9)   Class of security
Ordinary 10 pence shares


10)  Date of transaction
17 December 2004


11)  Date company informed
20 December 2004


12)  Total holding following this notification
10,217,983



13)  Total percentage holding of issued class following this notification
19.86%


14)  Any additional information
None


15)  Name of contact and telephone number for queries
Justin Hoskins 01223 898589


16)  Name and signature of authorised company official responsible for
     making this notification

Diane Mellett, Company Secretary

     Date of notification 21 December 2004





                      This information is provided by RNS
            The company news service from the London Stock Exchange
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