By Josie Cox 

European stock markets turned lower Monday as lingering concerns over the health of global economies, coupled with uncertainty surrounding debt negotiations in Greece, kept investors on edge.

After rising cautiously in early trade, the Stoxx Europe 600 index slipped into negative territory midmorning, extending sharp declines from Friday, which were triggered by data showing that eurozone consumer prices fell more in January than during any other month since July 2009.

Meanwhile the eurozone's manufacturing activity remained close to stagnation in January. Data firm Markit, which surveys more than 3,000 manufacturers across the eurozone, said Monday its purchasing managers index rose to 51.0 in January from 50.6 in December. A reading below 50.0 indicates activity is declining, while a reading above that level indicates it is increasing.

U.S. futures pointed to a largely steady open, after markets declined Friday, burdened by figures that showed economic growth in the country retreated to a modest pace in the final months of 2014. In Asia, numbers out of China over the weekend, suggested the country's manufacturing sector contracted in January for the first time in two years, sending the yuan to an eight-month low against the U.S. dollar.

"There is not a lot to be happy about," Rabobank strategists wrote in a note. The lackluster Chinese and U.S. data, they said, signals that from a growth perspective, "the world's two main engines are both losing power at the same time."

Further unsettling markets, Athens's new antiausterity government begins a push this month to convince eurozone countries to ease the terms under which it received large international financial rescues in recent years. Options include reducing Greece's budget constraints and debt-service burdens.

Relations between Greece and the rest of the eurozone have been rocky since the left-wing Syriza party won Greek elections on Jan. 25 and have triggered major swings in debt and stock markets since.

"We believe that the likelihood of a Greek exit from the [eurozone] is now significantly higher than at any point in 2012, in view of the latest political events," Barclays economists wrote in a note.

Athens' main stock exchange was trading 4.7% higher early afternoon Monday, cheered by efforts over the weekend from the government to calm jitters, but it is still around 8% lower so far this year and down almost 35% over the last six months. The yield on the Greek two-year bond remained above 19% on Monday, close to a euro-era high.

By contrast, the yield on the German bund, generally considered one of the lowest risk assets to invest in during times of stress, continued to hover around 0.3%, close to an all-time low. Bond yields fall as prices rise.

Greece's Eurobank Ergasias SA, one of the banks whose shares have been hit hardest in recent days, said over the weekend that its chairman and chief executive had resigned sending its shares more than 20% higher. Nonetheless, Eurobank's shares are still down 27% this year and a staggering 61% over the last six months.

In currency markets, the euro was marginally higher against the dollar in early trade Monday at around $1.1320.

The Swiss franc slipped almost 1.5% against the euro, with strategists citing unconfirmed media reports over the weekend that the Swiss National Bank has an inofficial corridor of 1.05-1.10 for the franc against the single currency in mind.

The franc rocketed last month after the SNB shocked markets by announcing it was scrapping a cap, especially souring the outlook for the country's exporters. The euro is currently trading around 1.0550 francs.

Elsewhere the ruble slid against the dollar Monday. On Saturday, Russia's economy minister said that the country's gross domestic product is expected to shrink by 3% in 2015 with oil prices at $50 a barrel and an estimated capital outflow at $115 billion, Russian news agencies reported.

On Friday the ruble hit a 2015 low after the country's central bank cut interest rates. It is currently trading around 70.19 rubles to the buck.

In commodity markets, Brent crude rose 1.2% to $53.60 a barrel, retracing a rally Friday. Gold was 0.5% lower at $1,273 a troy ounce.

Write to Josie Cox at josie.cox@wsj.com

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