FORM 5
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
[ ] Form 3 Holdings Reported
[ ] Form 4 Transactions Reported		 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

ANNUAL STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Lawrence Stephen J		2. Issuer Name and Ticker or Trading Symbol

WESBANCO INC [WSBC]		 5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
EVP & Chief Internal Auditor
(Last)          (First)          (Middle)

C/O WESBANCO,  ONE BANK PLAZA		3. Statement for Issuer's Fiscal Year Ended (MM/DD/YYYY)
12/31/2022 
(Street)

WHEELING, WV 26003
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed(MM/DD/YYYY)
 
6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form Filed by One Reporting Person
___ Form Filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		2. Trans. Date2A. Deemed Execution Date, if any3. Trans. Code
(Instr. 8)		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Amount(A) or (D)Price
Common Stock        21848.524 (1)D  
Common Stock        29788.082 (2)I by KSOP 
Common Stock        575 I By Spouse 401K 

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date
(MM/DD/YYYY)		7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of Derivative Securities Beneficially Owned at End of Issuer's Fiscal Year
(Instr. 4)		10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		11. Nature of Indirect Beneficial Ownership
(Instr. 4)
(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option $32.37          (3)5/25/2023 Common Stock 2000  2000 D  
Stock Option $21.55          (4)5/27/2027 Common Stock 2000  2000 D  
Stock Option $38.88          (5)5/16/2024 Common Stock 2000  2000 D  
Stock Option $45.65          (6)5/16/2025 Common Stock 2000  2000 D  
Stock Option $38.93          (7)5/15/2026 Common Stock 2000  2000 D  
Stock Option $38.78          (8)5/19/2028 Common Stock 2000  2000 D  
Stock Option $32.30          (9)5/18/2029 Common Stock 2000  2000 D  
Explanation of Responses:
(1) Includes 862.019 shares acquired from the WesBanco, Inc. Dividend Reinvestment Plan.
(2) Includes 1,959.585 shares credited to reporting person's KSOP account.
(3) Options vested in 2 equal installments beginning 12/31/16.
(4) Options vested in 2 equal installments beginning 12/31/20.
(5) Options vested in 2 equal installments beginning 12/31/17.
(6) Options vested in 2 equal installments beginning 12/31/18.
(7) Options vested in 2 equal installments beginning 12/31/19.
(8) Options vested in 2 equal installments beginning 12/31/21.
(9) Options vest in 2 equal installments on May 18, 2023 and December 31, 2023.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Lawrence Stephen J
C/O WESBANCO
ONE BANK PLAZA
WHEELING, WV 26003

EVP & Chief Internal Auditor
Signatures
/s/ Daniel K. Weiss, Attorney-in-Fact2/7/2023
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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