By Matt Grossman

 

Protagonist Therapeutics Inc.'s clinical studies for its rusfertide drug have been placed on a clinical hold by the U.S. Food and Drug Administration because of a recent finding in a mouse-model study, the company said Friday.

Benign and malignant skin tumors were observed in the mouse-model study, Protagonist said.

Dosing of patients has been put on hold, the Newark, Calif.-based pharmaceutical company said. Rusfertide was being tested in three Phase 2 trials, to treat polycthemia vera--a type of blood caner--and hereditary hemochromatosis, or iron overload.

Protagonist said it will work with the FDA to make any necessary updates to study protocols.

 

Write to Matt Grossman at matt.grossman@wsj.com

 

(END) Dow Jones Newswires

September 17, 2021 07:36 ET (11:36 GMT)

Copyright (c) 2021 Dow Jones & Company, Inc.
Protagonist Therapeutics (NASDAQ:PTGX)
Historical Stock Chart
From Sep 2021 to Oct 2021 Click Here for more Protagonist Therapeutics Charts.
Protagonist Therapeutics (NASDAQ:PTGX)
Historical Stock Chart
From Oct 2020 to Oct 2021 Click Here for more Protagonist Therapeutics Charts.