SAN
DIEGO, Nov. 14, 2024 /PRNewswire/ -- Inhibrx
Biosciences, Inc. (Nasdaq: INBX) ("Inhibrx Biosciences" or the
"Company") today reported financial results for the third
quarter of 2024. Following the completion of the sale of INBRX-101
by Inhibrx, Inc. (the "Former Parent") to Sanofi S.A. and the
Former Parent's concurrent spin-off of the Inhibrx Biosciences
business in May 2024, the
biopharmaceutical company now has two programs in ongoing clinical
trials, with data readouts for each expected within the next 12
months. Because the spin-off was accounted for as a reverse
spin-off, for periods prior to the spin-off, the Company's
financial statements are the historical financial statements of the
Former Parent.
Financial Results
- Cash and Cash Equivalents. As of
September 30, 2024, Inhibrx
Biosciences had cash and cash equivalents of $196.3 million, compared to $226.9 million as of June
30, 2024. Cash outflows in the period primarily consisted of
payments for its ongoing operations, including payments made to its
third party contract development and manufacturing organizations
("CDMOs") and contract research organizations ("CROs") in support
of the Company's ongoing clinical trials.
- R&D Expense. Research and development
expenses were $38.9 million during
the third quarter of 2024, compared to $38.1
million during the third quarter of 2023. The increase in
research and development expenses was primarily due to:
- an increase in clinical trial expenses due to the expansion of
the Company's ongoing registration-enabling Phase 2 trial
for ozekibart (INBRX-109) for the treatment of unresectable or
metastatic conventional chondrosarcoma. Clinical trial expenses
also increased as a result of the expansion of the INBRX-106 Phase
1/2 trial and the initiation of the Phase 2/3 trial in head and
neck squamous cell carcinoma, including expenses for in-house
clinical trial support;
- offset in part by a decrease in stock option expense as a
result of fewer stock options outstanding in the current period
under the Company's new 2024 Omnibus Incentive Plan (the "2024
Plan") following the termination of its prior plan in connection
with the spin-off.
- G&A Expense. General and administrative
expenses were $7.9 million during
each of the third quarters of 2024 and 2023. The composition of
general and administrative expenses fluctuated due to:
- a decrease in stock option expense as a result of fewer stock
options outstanding in the current period under the 2024 Plan
following the termination of its prior plan in connection with the
spin-off;
- offset by an increase in professional service expenses related
to legal and accounting services to support general corporate and
intellectual property matters as well as legal proceedings.
- Other Income (Expense). Other income was
$2.9 million during the third quarter
of 2024, compared to other expense of $6.0
million during the third quarter of 2023. Following the
Company's spin-off transaction in the second quarter of 2024, the
Company no longer has any outstanding third-party debt, and
therefore did not incur any interest expense during the period.
Other income consists of interest earned on the Company's sweep and
money market account balances.
- Net Loss. Net loss was $43.9 million during the third quarter of 2024,
or $2.84 per share, basic and
diluted, compared to a net loss of $51.8
million during the third quarter of 2023, or $4.39 per share, basic and diluted.
About Inhibrx Biosciences, Inc.
Inhibrx Biosciences is a clinical-stage biopharmaceutical
company focused on developing a broad pipeline of novel biologic
therapeutic candidates. Inhibrx Biosciences utilizes diverse
methods of protein engineering to address the specific requirements
of complex target and disease biology, including its proprietary
protein engineering platforms. Inhibrx Biosciences was incorporated
in January 2024 as a direct,
wholly-owned subsidiary of Inhibrx, Inc. Prior to the sale of
Inhibrx, Inc. and the INBRX-101 program to Sanofi S.A., Inhibrx
Biosciences acquired certain corporate infrastructure and other
assets and liabilities through a series of internal restructuring
transactions effected by Inhibrx, Inc. Inhibrx, Inc. also completed
a distribution to holders of its shares of common stock of 92% of
the issued and outstanding shares of Inhibrx Biosciences. Following
such transactions, Inhibrx Biosciences' current clinical pipeline
of therapeutic candidates includes ozekibart (INBRX-109) and
INBRX-106, both of which utilize multivalent formats where the
precise valency can be optimized in a target-centric way to mediate
what we believe to be the most appropriate agonist function. For
more information, please visit www.inhibrx.com.
Forward Looking Statements
Inhibrx Biosciences cautions you that statements contained in
this press release regarding matters that are not historical facts
are forward-looking statements. These statements are based on
Inhibrx Biosciences' current beliefs and expectations. These
forward-looking statements include, but are not limited to,
statements regarding expected data readouts and the timing thereof
and the Company's ability to develop therapeutic candidates. Actual
results may differ from those set forth in this press release due
to the risks and uncertainties inherent in Inhibrx Biosciences'
business, including, without limitation, risks and uncertainties
regarding: the initiation, timing, progress and results of its
preclinical studies and clinical trials, and its research and
development programs; its ability to advance therapeutic candidates
into, and successfully complete, clinical trials; the Company's
ability to utilize the Company's technology platform to generate
and advance additional therapeutic candidates; the implementation
of the Company's business model and strategic plans for the
Company's business and therapeutic candidates; the scope of
protection the Company is able to establish and maintain for
intellectual property rights covering the Company's therapeutic
candidates; the ability to raise funds needed to satisfy the
Company's capital requirements, which may depend on financial,
economic and market conditions and other factors, over which the
Company may have no or limited control; the Company's financial
performance; developments relating to the Company's competitors and
the Company's industry; and other risks described from time to time
in the "Risk Factors" section of its filings with the U.S.
Securities and Exchange Commission, including those described in
its Registration Statement on Form 10, as amended (File No.
001-42031), its Registration Statement on Form S-1, as amended and
supplemented from time to time (File No. 333-280127), and its
Quarterly Reports on Form 10-Q, and supplemented from time to time
by its Current Reports on Form 8-K as filed from time to time. You
are cautioned not to place undue reliance on these forward-looking
statements, which speak only as of the date hereof, and Inhibrx
Biosciences undertakes no obligation to update these statements to
reflect events that occur or circumstances that exist after the
date hereof. All forward-looking statements are qualified in their
entirety by this cautionary statement, which is made under the safe
harbor provisions of the Private Securities Litigation Reform Act
of 1995.
Investor and Media Contact:
Kelly D. Deck
Chief Financial Officer
ir@inhibrx.com
858-795-4260
Inhibrx Biosciences,
Inc
Condensed Consolidated Statements of Operations
(In thousands, except per share data)
(Unaudited)
|
|
|
THREE MONTHS
ENDED
SEPTEMBER
30,
|
|
NINE MONTHS
ENDED
SEPTEMBER
30,
|
|
2024
|
|
2023
|
|
2024
|
|
2023
|
Revenue:
|
|
|
|
|
|
|
|
License fee
revenue
|
$
—
|
|
$
119
|
|
$
100
|
|
$
166
|
Total
revenue
|
—
|
|
119
|
|
100
|
|
166
|
Operating
expenses:
|
|
|
|
|
|
|
|
Research and
development
|
38,893
|
|
38,057
|
|
170,376
|
|
109,549
|
General and
administrative
|
7,904
|
|
7,889
|
|
111,244
|
|
21,549
|
Total operating
expenses
|
46,797
|
|
45,946
|
|
281,620
|
|
131,098
|
Loss from
operations
|
(46,797)
|
|
(45,827)
|
|
(281,520)
|
|
(130,932)
|
Total other income
(expense)
|
2,933
|
|
(5,960)
|
|
2,016,959
|
|
(16,818)
|
Provision for income
taxes
|
—
|
|
2
|
|
2
|
|
7
|
Net income
(loss)
|
$
(43,864)
|
|
$
(51,789)
|
|
$
1,735,437
|
|
$
(147,757)
|
Earnings (loss) per
share
|
|
|
|
|
|
|
|
Basic
|
$
(2.84)
|
|
$
(4.39)
|
|
$
119.04
|
|
$
(13.19)
|
Diluted
|
$
(2.84)
|
|
$
(4.39)
|
|
$
117.09
|
|
$
(13.19)
|
Shares used in
computing earnings
(loss) per share
|
|
|
|
|
|
|
|
Basic
|
15,468
|
|
11,788
|
|
14,578
|
|
11,201
|
Diluted
|
15,468
|
|
11,788
|
|
14,821
|
|
11,201
|
Inhibrx Biosciences,
Inc
Condensed Consolidated Balance Sheets
(In
thousands)
(Unaudited)
|
|
|
SEPTEMBER
30,
|
|
DECEMBER
31,
|
|
2024
|
|
2023
|
Cash and cash
equivalents
|
$
196,332
|
|
$
277,924
|
Other current
assets
|
11,114
|
|
17,434
|
Non-current
assets
|
15,116
|
|
12,535
|
Total
assets
|
$
222,562
|
|
$
307,893
|
|
|
|
|
Debt, current and
non-current
|
$
—
|
|
$
206,968
|
Other current
liabilities
|
44,095
|
|
56,312
|
Other non-current
liabilities
|
—
|
|
1,110
|
Total
liabilities
|
44,095
|
|
264,390
|
Stockholders'
equity
|
178,467
|
|
43,503
|
Total liabilities and
stockholders' equity
|
$
222,562
|
|
$
307,893
|
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SOURCE Inhibrx Biosciences, Inc.