RNS Number:9628S
CeNeS Pharmaceuticals PLC
08 December 2003

                   CENES PHARMACEUTICALS PLC ("the Company")

                             HOLDING IN COMPANY

Following announcement by the Company on 24 November 2003, GlaxoSmithKline plc
has a notifiable interest in 13,284,508 ordinary shares of 1p each, representing
5.03% of the current issued share capital of the Company.


This holding is registered as follows:


                                           No. of Ordinary   % of issued Share
                                           Shares            Capital


SmithKline Beecham Corporation             5,789,920         2.31
Glaxo Group Limited                        7,494,588         2.99

GlaxoSmithKline plc total holding          13,284,508        5.30



Further information

Neil Clark, CeNeS Pharmaceuticals plc                    01223 266 466



5 December 2003


                      This information is provided by RNS
            The company news service from the London Stock Exchange

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