FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Posard Matthew L.

2. Date of Event Requiring Statement (MM/DD/YYYY)
2/2/2012 

3. Issuer Name and Ticker or Trading Symbol

ILLUMINA INC [ILMN]

(Last)        (First)        (Middle)

5200 ILLUMINA WAY

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
___ X ___ Officer (give title below)          _____ Other (specify below)
Sr VP & GM, Consumer Genomics /

(Street)

SAN DIEGO, CA 92122       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock   16807.0   (1) D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy)   2/25/2007   (2) 1/25/2017   Common Stock   8334.0   $20.04   D    
Non-Qualified Stock Option (right to buy)   2/28/2009   (3) 1/28/2019   Common Stock   17580.0   $28.45   D    
Non-Qualified Stock Option (right to buy)   2/29/2008   (3) 1/29/2018   Common Stock   5032.0   $32.485   D    
Non-Qualified Stock Option (right to buy)   2/27/2010   (3) 1/27/2020   Common Stock   27415.0   $37.04   D    
Non-Qualified Stock Option (right to buy)   2/28/2011   (3) 1/31/2021   Common Stock   36225.0   $69.34   D    

Explanation of Responses:
( 1)  Includes 8,636 unvested restricted stock units which vest as follows: 1,512 shares vest on 1/27/12; 1,960 shares vest on 1/28/12; 800 shares vest on 1/31/12; 1,764 shares vest on 1/27/13; 1,200 shares vest on 1/31/13; 1,400 shares vest on 1/31/14.
( 2)  One -sixtieth (1/60) of the Shares subject to the Option become exercisable on the date indicated above, subject to Optionee's continuing to be a Service Provider on such date. An additional one -sixtieth (1/60) of the Shares subject to the Option shall become exercisable each full month therafter, subject to Optionee's continuing to be a Service Provider on such date.
( 3)  One forty-eighth (1/48) of the Shares subject to the Option become exercisable on the date indicated above, subject to Optionee's continuing to be a Service Provider on such date. An additional one-forty eighth (1/48) of the Shares subject to the Option shall become exercisable each full month therafter, subject to Optionee's continuing to be a Service Provider on such date.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Posard Matthew L.
5200 ILLUMINA WAY
SAN DIEGO, CA 92122


Sr VP & GM, Consumer Genomics

Signatures
By: Scott M. Davies For: Matthew L. Posard 3/7/2012
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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