Roche Holding AG's (ROG.VX) Monday extended its buyout offer for U.S. diagnostics company Illumina Inc. (ILMN) until March 23 without changing the terms of its hostile bid, a move that was expected and is consistent with the Swiss pharmaceutical giant's past M&A strategy.

Roche is bidding $44.50 a share for the San Diego-based group, an offer it views as "full and fair," but one that Illumina has dismissed as too low. The Basel-based company said Monday that it is still offering the same price for Illumina shares, valuing the buyout at $5.7 billion, with the period now extended to 6:00 p.m., New York City time, on March 23.

Roche has a history of success with hostile acquisitions and also faces little risk of that rival bidders will jump into the fray.

Earlier buys by the world's leading cancer drug maker, such as that of diagnostic test-maker Ventana or U.S. biotech group Genentech, indicate that Roche is content to take its time with deals and that it will ultimately prevail with a sweetened offer.

Roche took seven months to buy Ventana for $3.4 billion in 2008. A year later the Swiss firm fully acquired Genentech, paying $46.8 billion to acquire the 44% of Genentech Inc. that it didn't already own after a protracted and bumpy takeover process.

"It may take six to 12 months and a sweetened offer," but Roche will win in the end, Bank Vontobel said Monday.

Most analysts agree and see an eventual deal done in the region of $60-$65 for each Illumina share.

The California-based target remained frosty toward Roche's overtures, saying that "the extension by Roche was expected."

Illumina's icy stance might be understandable given that the company's stock as recently as last summer traded in the region of $70 a share.

Responding to Roche's tender offer extension, Illumina said that "an extremely low number of shares have been tendered, consistent with our view--and that of our stockholders--that Roche's offer does not reflect Illumina unique leadership position, business performance and future prospects."

Only around 0.1% of Illumina's stock--some 102,165 shares--have so far been tendered to Roche, the Swiss company said.

Roche shares at 0850 were down CHF1.1, or 0.6%, at CHF158.30 but up 15% from year-ago levels.

Illumina shares ended Friday down 0.9% at $51.22.

-By Sten Stovall, Dow Jones Newswires; +44 207 842 9292; sten.stovall@dowjones.com

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