FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public
Utility Holding Company Act of 1935 or Section 30(f) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Metza Kristen
2. Issuer Name and Ticker or Trading Symbol

GILEAD SCIENCES INC [ GILD ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
SVP, Human Resources
(Last)          (First)          (Middle)

GILEAD SCIENCES, INC., 333 LAKESIDE DRIVE
3. Date of Earliest Transaction (MM/DD/YYYY)

9/16/2011
(Street)

FOSTER CITY, CA 94404
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   9/16/2011     M    4500   A $28.26   22298   D    
Common Stock   9/16/2011     M    500   A $30.945   22798   D    
Common Stock   9/16/2011     S    5000   D $40.3   17798   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (Right to Buy)   $28.26   9/16/2011     M         4500      (1) 5/9/2016   Common Stock   4500   $ 0   0   D    
Non-Qualified Stock Option (Right to Buy)   $30.945   9/16/2011     M         500      (2) 7/26/2016   Common Stock   500   $ 0   11500   D    

Explanation of Responses:
( 1)  The stock options have a five year vesting schedule. 20% of the options vested on May 9, 2007, the first anniversary of the grant. The balance vested 5% quarterly thereafter until fully vested on May 9, 2011. The options expire on May 9, 2016.
( 2)  The stock options have a five year vesting schedule. 20% of the options vested on July 26, 2007, the first anniversary of the grant. The balance vested 5% quarterly thereafter until fully vested on July 26, 2011. The options expire on July 26, 2016.

Remarks:
Exhibit List: Exhibit 24 - The reporting person has signed a new power of attorney dated July 18, 2011. The exercise and sale transactions reported in this Form 4 made pursuant to a Rule 10b5-1 trading plan established by Ms. Metza on February 22, 2011.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Metza Kristen
GILEAD SCIENCES, INC.
333 LAKESIDE DRIVE
FOSTER CITY, CA 94404


SVP, Human Resources

Signatures
/s/ Kristen M. Metza 9/20/2011
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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