SECURITIES & EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G
(Rule 13d-102)

INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
TO RULES 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED
PURSUANT TO 13d-2(b)

(Amendment No. )*

Avigen, Inc.
(Name of Issuer)

Common Stock, $0.001 par value per share
(Title of Class of Securities)

053690103
(CUSIP Number)

May 5, 2008
(Date of event which requires filing of this statement)

Check the appropriate box to designate the rule pursuant to which this
Schedule is filed:

[ ] Rule 13d-1(b)
[x] Rule 13d-1(c)
[ ] Rule 13d-1(d)

(Page 1 of 14 Pages)

*The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be "filed" for purposes of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).


CUSIP No. 053690103 13G Page 2 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor Management, L.P.

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
 20-2893581
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 1,950,000
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 1,950,000
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 1,950,000
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 6.55%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 PN
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 3 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor Asssociates, LLC

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
 20-2891849
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 1,950,000
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 1,950,000
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 1,950,000
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 6.55%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 OO - limited liability company
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 4 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor Offshore, Ltd.

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Cayman Islands
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 1,287,011
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 1,287,011
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 1,287,011
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 4.32%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 OO - limited company
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 5 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor Hybrid Offshore, Ltd.

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Cayman Islands
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 289,875
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 289,875
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 289,875
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 0.97%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 OO - limited company
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 6 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor Group, LLC

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
 51-0551771
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 373,114
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 373,114
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 373,114
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 1.25%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 OO - limited liability company
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 7 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor Capital, L.P.

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
 51-0551770
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 373,114
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 373,114
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 373,114
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 1.25%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 PN
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 8 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 HealthCor, L.P.

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
 20-3240266
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 Delaware
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 373,114
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 373,114
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 373,114
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 1.25%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 PN
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 9 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 Arthur Cohen

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 United States
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 1,950,000
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 1,950,000
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 1,950,000
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 6.55%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 IN
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 10 of 14 Pages


-----------------------------------------------------------------------------
 (1) NAMES OF REPORTING PERSONS
 Joseph Healey

 I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY)
-----------------------------------------------------------------------------
 (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP **
 (a) [X]
 (b) [ ]
-----------------------------------------------------------------------------
 (3) SEC USE ONLY
-----------------------------------------------------------------------------
 (4) CITIZENSHIP OR PLACE OF ORGANIZATION
 United States
-----------------------------------------------------------------------------
NUMBER OF (5) SOLE VOTING POWER
 0
SHARES --------------------------------------------------------------

BENEFICIALLY (6) SHARED VOTING POWER
 1,950,000
OWNED BY --------------------------------------------------------------

EACH (7) SOLE DISPOSITIVE POWER
 0
REPORTING --------------------------------------------------------------

PERSON WITH (8) SHARED DISPOSITIVE POWER
 1,950,000
-----------------------------------------------------------------------------
 (9) AGGREGATE AMOUNT BENEFICIALLY OWNED
 BY EACH REPORTING PERSON
 1,950,000
-----------------------------------------------------------------------------
 (10) CHECK BOX IF THE AGGREGATE AMOUNT
 IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ]
-----------------------------------------------------------------------------
 (11) PERCENT OF CLASS REPRESENTED
 BY AMOUNT IN ROW (9)
 6.55%
-----------------------------------------------------------------------------
 (12) TYPE OF REPORTING PERSON **
 IN
-----------------------------------------------------------------------------
 ** SEE INSTRUCTIONS BEFORE FILLING OUT!


CUSIP No. 053690103 13G Page 11 of 14 Pages


Item 1(a). Name of Issuer:
 Avigen, Inc.


Item 1(b). Address of Issuer's Principal Executive Offices:
 1301 Harbor Bay Parkway
 Alameda, CA 94502

Item 2(a, b, c). Name of Person Filing:

 (i) HealthCor Management, L.P., a Delaware limited partnership;
 Carnegie Hall Tower, 152 West 57th Street, 47th Floor, New York,
 New York 10019;

 (ii) HealthCor Associates, LLC, a Delaware limited liability
 company, Carnegie Hall Tower, 152 West 57th Street, 47th Floor,
 New York, New York 10019;

 (iii) HealthCor Offshore, Ltd., a Cayman Islands limited company,
 Carnegie Hall Tower, 152 West 57th Street, 47th Floor, New York,
 New York 10019;

 (iv) HealthCor Hybrid Offshore, Ltd., a Cayman Islands limited
 company, Carnegie Hall Tower, 152 West 57th Street, 47th Floor,
 New York, New York 10019;

 (v) HealthCor Group, LLC, a Delaware limited liability company,
 Carnegie Hall Tower, 152 West 57th Street, 47th Floor, New York,
 New York 10019;

 (vi) HealthCor Capital, L.P., a Delaware limited partnership,
 Carnegie Hall Tower, 152 West 57th Street, 47th Floor, New York,
 New York 10019;

 (vii) HealthCor, L.P., a Delaware limited partnership, Carnegie
 Hall Tower, 152 West 57th Street, 47th Floor, New York, New York
 10019;

 (viii) Joseph Healey; Carnegie Hall Tower, 152 West 57th Street,
 47th Floor, New York, New York 10019; and

 (ix) Arthur Cohen, 12 South Main Street, #203 Norwalk, Ct 06854.
 Both Mr. Healey and Mr. Cohen are United States citizens.

 The persons at (i) through (ix) above are collectively referred
 to herein as the "Reporting Persons".

Item 2(d). Title of Class of Securities:
 common stock, par value $0.001 per share (the "Common Stock")

Item 2(e). CUSIP Number:
 053690103


Item 3. Not applicable.


CUSIP No. 053690103 13G Page 12 of 14 Pages

Item 4. Ownership.

 The information required by Items 4(a) - (c) is set forth in Rows
 5 - 11 of the cover page for each Reporting Person hereto and is
 incorporated herein by reference for each such Reporting Person.

 Collectively, HealthCor, L.P., Healthcore Offshore, Ltd. and
 HealthCor Hybrid Offshore, Ltd. (each a "Fund" and together, the
 "Funds") are the beneficial owners of a total of 1,950,000 shares
 of the Common Stock of the Issuer. By virtue of its position as
 the investment manager of the Funds, HealthCor Management, L.P.
 may be deemed a beneficial owner of all the shares of Common
 Stock owned by the Funds. HealthCor Associates, LLC is the
 general partner of HealthCor Management, L.P. and thus may also
 be deemed to beneficially own the shares of Common Stock that are
 beneficially owned by the Funds.

 HealthCor Group LLC is the general partner of HealthCor Capital,
 L.P., which is in turn the general partner of HealthCor, L.P.
 Accordingly, each of HealthCor Capital L.P. and HealthCor Group,
 LLC may be deemed to beneficially own the shares of Common Stock
 that are beneficially owned by HealthCor, L.P.

 As the Managers of HealthCor Associates, LLC, Arthur Cohen and
 Joseph Healey exercise both voting and investment power with
 respect to the shares of Common Stock reported herein, and
 therefore each may be deemed a beneficial owner of such Common
 Stock.

 Each of the Reporting Persons hereby disclaims any beneficial
 ownership of any such Shares in excess of their actual pecuniary
 interest therein.


Item 5. Ownership of Five Percent or Less of a Class:

 If this statement is being filed to report the fact that as of
 the date hereof the reporting person has ceased to be the
 beneficial owner of more than five percent of the class of
 securities, check the following [ ].

Item 6. Ownership of More than Five Percent on Behalf of Another Person.
 Not Applicable

Item 7. Identification and Classification of the Subsidiary Which
 Acquired the Security Being Reported on by the Parent Holding
 Company.
 Not Applicable

Item 8. Identification and Classification of Members of the Group.
 Not Applicable

Item 9. Notice of Dissolution of Group.
 Not Applicable


CUSIP No. 053690103 13G Page 13 of 14 Pages

Item 10. Certification.

 By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing the control of
the issuer of the securities and were not acquired and are not held in
connection with or as a participant in any transaction having that purpose or
effect.


CUSIP No. 053690103 13G Page 14 of 14 Pages

 SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify
that the information set forth in this statement is true, complete and correct.

DATED: May 14, 2008

 HEALTHCOR MANAGEMENT, L.P., for itself and
 as manager on behalf of (i) HEALTHCOR
 OFFSHORE, LTD. and (ii) HEALTHCOR HYBRID
 OFFSHORE, LTD.

 By: HealthCor Associates, LLC, its general
 partner

 By: /s/ Steven J. Musumeci
 -------------------------------------
 Name: Steven J. Musumeci
 Title: Chief Operating Officer


 HEALTHCOR CAPITAL L.P., for itself and as
 manager on behalf of HEALTHCOR L.P.

 By: HealthCor Group, LLC, its general partner

 By: /s/ Steven J. Musumeci
 -------------------------------------
 Name: Steven J. Musumeci
 Title: Chief Operating Officer


 HEALTHCOR ASSOCIATES, LLC

 By: /s/ Steven J. Musumeci
 ----------------------
 Name: Steven J. Musumeci
 Title: Chief Operating Officer


 HEALTHCOR GROUP, LLC

 By: /s/ Steven J. Musumeci
 ----------------------
 Name: Steven J. Musumeci
 Title: Chief Operating Officer


 /s/ Joseph Healey
 ------------------
 JOSEPH HEALEY, Individually


 /s/ Arthur Cohen
 ------------------
 ARTHUR COHEN, Individually

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