FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

SCHMERTZLER MICHAEL 		2. Issuer Name and Ticker or Trading Symbol

PTC THERAPEUTICS, INC. [ PTCT ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      _____ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

1300 VALLEY ROAD 		3. Date of Earliest Transaction (MM/DD/YYYY)

9/23/2016
(Street)

NEW CANAAN, CT 06840
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   9/23/2016     M    60000   A $10.85   86766   (1) D    
Common Stock                  1320369   I   See footnote   (2)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)   $10.85   9/23/2016     M         60000      (3) 5/15/2023   Common Stock   60000   $0   0   D    
Stock Option (Right to Buy)   $30.86                      (4) 1/3/2026   Common Stock   24000     24000   D    
Stock Option (Right to Buy)   $51                    1/2/2016   1/1/2025   Common Stock   24000     24000   D    
Stock Option (Right to Buy)   $27.05                    1/28/2015   1/27/2024   Common Stock   20000     20000   D    
Stock Option (Right to Buy)   $218.4                      (3) 1/10/2022   Common Stock   276     276   D    
Stock Option (Right to Buy)   $490.8                      (3) 4/27/2021   Common Stock   276     276   D    
Stock Option (Right to Buy)   $1149.6                      (3) 2/2/2020   Common Stock   216     216   D    
Stock Option (Right to Buy)   $508.8                      (3) 10/7/2019   Common Stock   266     266   D    
Stock Option (Right to Buy)   $735.6                      (3) 1/25/2018   Common Stock   166     166   D    
Stock Option (Right to Buy)   $735.6                      (3) 7/14/2018   Common Stock   83     83   D    
Stock Option (Right to Buy)   $626.4                      (3) 4/18/2017   Common Stock   125     125   D    

Explanation of Responses:
( 1)  Represents 86,766 shares of common stock of the Issuer ("common stock") directly held by the reporting person.
( 2)  Represents shares of common stock held by Section Six Partners, L.P. The reporting person is a general and limited partner of, and trustee of certain family trusts holding interests in, Section Six Partners, L.P. The reporting person disclaims beneficial ownership of the shares of common stock held by Section Six Partners, L.P. except to the extent of his pecuniary interest therein.
( 3)  Currently exercisable.
( 4)  This option was awarded on January 4, 2016 and vests over one year in twelve equal monthly installments, commencing February 4, 2016.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
SCHMERTZLER MICHAEL
1300 VALLEY ROAD
NEW CANAAN, CT 06840 		X



Signatures
/s/ Colleen Diver Johnson, attorney-in-fact 9/26/2016
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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