Verona Pharma PLC 2014 Annual Report and Accounts and Notice of AGM (9910M)
May 13 2015 - 2:01AM
UK Regulatory
TIDMVRP
RNS Number : 9910M
Verona Pharma PLC
13 May 2015
Verona Pharma plc
("Verona Pharma" or the "Company")
2014 Annual Report and Accounts
and
Notice of AGM
13 May 2015, Cardiff- Verona Pharma plc (AIM: VRP), the drug
development company focused on first-in-class medicines to treat
respiratory diseases, confirms that it has made available the
Annual Report and Accounts for the year ended 31 December 2014
("2014 Annual Report and Accounts"). The report is available online
at:
http://www.veronapharma.com/joomla/index.php/investors/financial-performance.
A hard copy of the 2014 Annual Report and Accounts, the Notice
of AGM ("AGM") and a Form of Proxy will be posted to Shareholders
on 15 May 2015.
The AGM is to be held at 10:30am on 11 June 2015 at the offices
of SGH Martineau LLP, 5th Floor, One America Square, Crosswall,
London EC3N 2SG.
-Ends-
For further information please contact:
Verona Pharma plc Tel: +44 (0) 20 3283
4200
Jan-Anders Karlsson, Chief
Executive Officer
N+1 Singer Tel: +44 (0)20 7496 3000
Aubrey Powell / Jen Boorer
FTI Consulting Tel: +44 (0)20 3727 1000
Julia Phillips / Simon
Conway
Notes to Editors
About Verona Pharma plc
Verona Pharma plc is a UK-based clinical stage biopharmaceutical
company focused on the development of innovative prescription
medicines to treat respiratory diseases with significant unmet
medical needs, such as chronic obstructive pulmonary disease
(COPD), asthma and cystic fibrosis.
Verona Pharma's lead drug, RPL554, is a first-in-class drug
currently in phase II trials as a nebulised treatment for acute
exacerbations of COPD in the hospital setting. The drug is a dual
phosphodiesterase (PDE) 3/4 inhibitor and therefore has both
bronchodilator and anti-inflammatory effects, which are essential
to the improvement of patients with COPD and asthma.
Verona Pharma is also building a broader portfolio of
RPL554-containing products to maximise its benefit to patients and
its value. This includes the very significant markets for COPD and
asthma maintenance therapy. The Company is also exploring the
potential of the drug in different diseases, such as cystic
fibrosis, where it is in pre-clinical testing and has recently
received a Venture and Innovation Award from the Cystic Fibrosis
Trust.
About Chronic Obstructive Pulmonary Disease (COPD)
Sixty-five million people worldwide suffer from moderate to
severe COPD and the World Health Organisation (WHO) expects COPD to
be the 3rd leading cause of death globally by 2020. It is the only
major chronic disease with increasing mortality. Currently
available drugs are aimed at long-term maintenance therapy, with
the market dominated by large pharma. Despite the wide availability
of these therapies, COPD patients suffer acute periods of worsening
symptoms (exacerbations), which cause, in the US alone, some 1.5
million A&E visits, 726,000 hospitalisations and 120,000 deaths
per annum.
Bronchodilating therapy is considered to be the standard of
care, and agents can be administered via handheld devices such as
metered dose inhaler (MDI), dry powder inhaler (DPI) and by
nebulisers. The nebulised bronchodilator market was worth about $1
billion in 2014 in the US.(1) RPL554 is being developed by Verona
Pharma as an add-on therapy to the "Standard of Care" with the
objectives of providing rapid and pronounced improvement in lung
function, reduced symptoms and both shortened duration of hospital
stays and reduced re-admission rates 30 days after discharge from
hospital. Studies to date on RPL554 have demonstrated that it has a
strongly differentiated 3-way mode of action, being: (1)
bronchodilation (the relaxation of smooth muscle in the airway);
(2) anti-inflammatory effects on cells and (3) ion channel
activation in epithelial cells, with increased mucociliary
clearance of the airway.
(1) IMS Consulting Group market research 2014
This information is provided by RNS
The company news service from the London Stock Exchange
END
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