Holding(s) in Company

RNS Number:4472T
Lipoxen PLC
21 March 2007

LIPOXEN PLC (the "Company")

NOTIFICATION OF INTEREST IN TOTAL VOTING RIGHTS

A form TR-1 containing the following information has been received by the
Company.

TR-1 notification of major interests in shares

1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached:

LIPOXEN PLC

2. Reason for the notification

Notification for the FSA 20 March 2007 deadline.

3. Full name of person(s) subject to the notification obligation:

Gartmore Investment Limited

4. Full name of shareholder(s) (if different from 3):

GARTMORE SMALLER COMPANIES TRUST PLC 3.617%

5.Date of the transaction (and date on which the threshold

is crossed or reached if different):

N/A

6. Date on which issuer notified:

19 March 2007

7. Threshold(s) that is/are crossed or reached:

Below 5%

8. Notified details:

A: Voting rights attached to shares
Class/type of Situation previous to the Resulting situation after the triggering transaction(1)
shares Triggering transaction
Number of Number of Number of Number of voting rights % of voting rights
if possible using Shares Voting shares
the ISIN CODE Rights Direct Direct Indirect Direct Indirect
GB00B08NWV55 7% 8,387,301 nil 8,387,301 nil 7.234%

B: Financial Instruments
Resulting situation after the triggering transaction
Type of financial Expiration date Exercise/ Conversion Number of voting rights % of voting
instrument Period/ Date that may be acquired if rights
the instrument is
exercised/ converted.

Total (A+B)
Number of voting rights % of voting rights

8,387,301 7.234%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:

N/A

Proxy Voting:

10. Name of the Proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder cease to hold voting rights:

N/A

13. Additional information: