RNS Number:4210S
Alterian PLC
24 November 2003

                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

      ALTERIAN PLC

2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

      FLEMING MERCANTILE INVESTMENT TRUST PLC

3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

      HOLDING OF SHAREHOLDER IN 2 NAMED ABOVE

4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.


      FLEMING MERCANTILE INVESTMENT TRUST PLC

5)   Number of shares/amount of stock acquired.

      1,500,000

6)   Percentage of issued Class

      3.82%
7)   Number of shares/amount of stock disposed

      

8)   Percentage of issued Class


9)   Class of security

     ORDINARY SHARES OF 25P

10)  Date of transaction

      21/11/03

11)  Date company informed

      24/11/03

12)  Total holding following this notification

      1,500,000
               
13)  Total percentage holding of issued class following this notification

      3.82%

14)  Any additional information



15)  Name of contact and telephone number for queries

      SALLY ATTRYDE - (0117) 9703200

16)  Name and signature of authorised company official responsible for 
     making this notification

     Date of Notification 24 NOV 2003





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