Stem Cell Therapeutics Corp. Announces Publication of Phase IIa Stroke Data
March 10 2010 - 3:03PM
Marketwired
Stem Cell Therapeutics Corp. ("SCT" or the "Company") (TSX VENTURE:
SSS) wishes to announce the acceptance and publication of the paper
entitled "The Beta-hCG + Erythropoietin in Acute Stroke ( BETAS)
Study" by the journal "Stroke", on March 8, 2010. This paper was
authored by Dr. Steven C. Cramer, from the University of
California, Irvine, Dr. David Brown at Hoag Memorial Hospital
Presbyterian, New Port Beach, Dr. Michael D. Hill of Foothills
Hospital at the University of Calgary, and colleagues.
Dr. Allen Davidoff, VP of Product Development, commented as
follows:
"The Stroke journal, published by the American Heart
Association, is the top journal in the field of stroke research.
Stem Cell Therapeutics is pleased to congratulate Dr. Steven C.
Cramer, David Brown and Michael Hill for their efforts, acceptance
and successful publication of this novel study by this highly
respected, peer reviewed journal. Previously this work has only
appeared in abstracts. This publication marks another important
milestone in the development of NTx®-265 and provided the continued
evidence of clinical safety and the foundation for the proof of
concept study modified REGENESIS."
The BETAS study was designed as an open label trial to provide
the first evidence that NTx®-265 could be safely administered to
patients with acute ischemic stroke. A total of fifteen human
subjects at three centers were administered a course of NTx®-265,
sequential administration of human chorionic gandotropin (hCG)
followed by erythropoietin (EPO), with the first dose at 24-48
hours after stroke onset. Patients were then monitored for 90 days.
The study found that NTx®-265 appeared to be safe and patients
showed improved clinical outcomes compared to published data on
similar untreated stroke patients as well as a trend towards
reduced infarct volumes over time in comparison to data previously
described elsewhere. This preliminary examination of behavioural
and motor domains highlighted priority areas that will be important
to address in future studies. These results strongly support the
safety of NTx®-265 and provide evidence for the achievability of
this treatment in stroke.
About Stem Cell Therapeutics Corp.: Stem Cell Therapeutics Corp.
is a Canadian public biotechnology company (TSX VENTURE: SSS)
focused on the development and commercialization of drug-based
therapies to treat central nervous system diseases. SCT is a leader
in the development of therapies that utilize drugs to stimulate a
patient's own resident stem cells. The Company's programs aim to
repair brain and nerve function lost due to disease or injury. The
Company's extensive patent portfolio of owned and licensed
intellectual property supports the potential expansion into future
clinical programs in numerous neurological diseases such as
traumatic brain injury, multiple sclerosis, Huntington's disease,
Alzheimer's disease, and ALS.
These securities have not been registered under the United
States Securities Act of 1933, as amended, or the securities laws
of any state, and may not be offered or sold within the United
States or to, or for the account or benefit of U.S. persons unless
an applicable exemption from U.S. registration requirements is
available.
Except for historical information, this press release may
contain forward-looking statements, which reflect the Company's
current expectation regarding future events. These forward-looking
statements involve risk and uncertainties, which may cause but are
not limited to, changing market conditions, the successful and
timely completion of clinical studies, the establishment of
corporate alliances, the impact of competitive products and
pricing, new product development, uncertainties related to the
regulatory approval process and other risks detailed from time to
time in the Company's ongoing quarterly and annual reporting.
Neither TSX Venture Exchange nor its Regulation Services
Provider (as that term is defined in the policies of the TSX
Venture Exchange) accepts responsibility for the adequacy or
accuracy of this release.
Contacts: Stem Cell Therapeutics Corp. Alan Moore, PhD President
and CEO (403) 245-5495 ext. 224 amoore@stemcellthera.com Stem Cell
Therapeutics Corp. Angelika Goncalves DaSilva Operations Manager
(403) 245-5495 ext. 221 crampton@stemcellthera.com
www.stemcellthera.com
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