Item 5.02 Departure of Directors or Certain
Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
Appointment of President
and Chief Executive Officer and Chair of the Board
On February 17, 2023,
the Board of Directors (the “Board”) of Phio Pharmaceuticals Corp. (the “Company”) approved the appointment of
Robert J. Bitterman, acting Executive Chairman of the Board and acting Interim Chief Executive Officer, to serve as the Company’s
President and Chief Executive Officer and Chair of the Board, effective as of February 20, 2023. Mr. Bitterman will continue to serve
as the Company's principal executive officer and principal financial officer.
Mr. Bitterman, 71, has
served as a member and the Chairman of the Company’s Board since 2012 and as the Interim Executive Chairman of the Company since
September 2022. Mr. Bitterman served as the President and Chief Executive Officer of Cutanea Life Sciences, Inc., a private company he
founded in 2005 that focused on developing innovative technologies to treat diseases and disorders of the skin and subcutaneous tissue,
until its acquisition by Biofrontera, Inc., USA in March 2019. Since leaving Cutanea, Mr. Bitterman was retired until commencing the Interim
Executive Chairman role with the Company in September 2022. Prior to his role at Cutanea Life Sciences, Inc., Mr. Bitterman also held
the position of President and Chief Executive Officer of Isolagen, Inc., President and General Manager of Dermik Laboratories and various
positions of increasing responsibility in financial and commercial capacities within Aventis S.A. Mr. Bitterman holds an A.B. degree in
Economics from The College of the Holy Cross and a Master of Business Administration degree from Boston University. He also holds a Doctor
of Humane Letters (Honoris Causa) from the New York College of Podiatric Medicine.
In connection with Mr. Bitterman’s appointment
as the Company’s President and Chief Executive Officer, the Company entered into an employment agreement, dated and effective as
of February 20, 2023 (the “Employment Agreement”), with Mr. Bitterman that governs the terms of Mr. Bitterman’s employment
with the Company. The Employment Agreement provides that Mr. Bitterman will be entitled to an initial annual base salary of $440,000 (the
“Base Salary”) and will be eligible to receive an annual bonus of up to 40% of his annual base salary, based on the achievement
of certain performance goals established annually by the Board. In connection with his appointment, the Company granted Mr. Bitterman
restricted stock units (the “RSUs”) settleable for 11,000 shares of the Company's common stock, par value $0.0001 per share,
under the Company's 2020 Long Term Incentive Plan. The RSUs will vest in two equal annual installments, commencing on the first anniversary
of the date of grant, subject to Mr. Bitterman’s continuous service with the Company through each such vesting date.
If Mr. Bitterman’s employment is terminated by the Company due
to death or disability, the Company shall pay to Mr. Bitterman or to his estate, as applicable, any earned, but unpaid, Base Salary and
any amounts owed to Mr. Bitterman for reimbursement of expenses properly incurred which are reimbursable, in each case as earned or incurred,
as applicable through the date of termination (the “Accrued Benefits”), as well as pay any accrued but unpaid bonus then due
to Mr. Bitterman and all equity awards that have been granted will immediately vest on a pro-rata basis. If Mr. Bitterman’s employment
is terminated by the Board for cause or by Mr. Bitterman without good reason, the Company shall pay to Mr. Bitterman the Accrued Benefits
through the date of termination. If Mr. Bitterman’s employment is terminated by Mr. Bitterman for Good Reason (as defined in the
Employment Agreement) or by the Company other than as a result of death or disability and other than for cause, then the Company shall
pay to Mr. Bitterman the Accrued Benefits through the date of termination, continue to pay Mr. Bitterman his Base Salary for three months
from the date of separation, pay any accrued but unpaid bonus and if, and only if, such termination occurs within one year of a Change
in Control (as defined in the Employment Agreement) all equity awards that have been granted but are not exercisable at the time of such
termination shall immediately become exercisable in full.
Mr. Bitterman will also be eligible to participate in the Company’s
2020 Long Term Incentive Plan and other benefits available to the Company’s executive officers. In addition, the Company will enter
into an indemnification agreement with Mr. Bitterman on terms substantially similar to the terms of the form of indemnification agreement
filed as Exhibit 10.9 to the Company’s Annual Report on Form 10-K filed on March 22, 2022.
The foregoing summary of the Employment Agreement is qualified in its
entirety by reference to the full text of the Employment Agreement, a copy of which is filed with this Current Report on Form 8-K as Exhibit
10.1, and is incorporated herein by reference.
There are no family relationships between Mr.
Bitterman and any director or executive officer of the Company. There are no transactions between Mr. Bitterman and the Company that would
require disclosure under Item 404(a) of Regulation S-K.
Upon the effective date
of his appointment as President and Chief Executive Officer, Mr. Bitterman will remain on the Board as Chair.
On February 22, 2023,
the Company issued a press release announcing Mr. Bitterman’s appointment as the Company’s President and Chief Executive
Officer. The full text of the press release is furnished as Exhibit 99.1 hereto and incorporated herein by reference.