FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

McDonnell Loan Opportunity Ltd.

2. Date of Event Requiring Statement (MM/DD/YYYY)
6/27/2010 

3. Issuer Name and Ticker or Trading Symbol

Molecular Insight Pharmaceuticals, Inc. [MIPI]

(Last)        (First)        (Middle)

C/O MCDONNELL INVESTMENT MANAGEMENT, LLC, 1515 W. 22ND STREET

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
_____ Officer (give title below)          ___ X ___ Other (specify below)
/ See Remarks

(Street)

OAK BROOK, IL 60523       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
No non-derivative securities are beneficially owned.   0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Warrant for Common Stock   11/16/2007   11/16/2012   Common Stock, par value $0.01 per share   280992   $5.87   D    

Explanation of Responses:

Remarks:
The Reporting Person may be deemed to be a member of a "group" with certain other holders of equity securities and/or derivative securities of the Issuer for purposes of Section 13(d) of the Securities Exchange Act of 1934, as amended. If such a group were determined to exist, the members hold in the aggregate more than ten percent (10%) of the Issuer's equity securities. The Reporting Person disclaims the existence of such a group and disclaims beneficial ownership of any equity securities and/or derivative securities of the Issuer other than those set forth above. This report shall not be deemed an admission that any Reporting Person is a member of a Section 13(d) group, for the purposes of Section 16 or for any other purpose.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
McDonnell Loan Opportunity Ltd.
C/O MCDONNELL INVESTMENT MANAGEMENT, LLC
1515 W. 22ND STREET
OAK BROOK, IL 60523



See Remarks

Signatures
/s/ James R. Fellows, Managing Director, McDonnell Investment Management, LLC, as Investment Manager for McDonnell Loan Opportunity Ltd. 6/30/2010
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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