FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Anderson Erik S
2. Date of Event Requiring Statement (MM/DD/YYYY)
10/14/2022 

3. Issuer Name and Ticker or Trading Symbol

HOLOGIC INC [HOLX]
(Last)        (First)        (Middle)

250 CAMPUS DRIVE
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          _____ 10% Owner
___X___ Officer (give title below)        _____ Other (specify below)
Div. Pres., Breast & Skeletal /
(Street)

MARLBOROUGH, MA 01752      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 7587 (1)D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Non-qualified Stock Option (Right to Buy)  (2)12/1/2027 Common Stock 6418 $40.85 D  
Non-qualified Stock Option (Right to Buy)  (3)11/12/2028 Common Stock 6520 $40.97 D  
Non-qualified Stock Option (Right to Buy)  (4)3/20/2030 Common Stock 10518 $47.12 D  
Non-qualified Stock Option (Right to Buy)  (5)11/9/2030 Common Stock 4378 $68.35 D  
Non-qualified Stock Option (Right to Buy)  (6)11/8/2031 Common Stock 4160 $71.13 D  

Explanation of Responses:
(1) Includes restricted stock unit awards which vest in equal installments on each of the first three anniversaries of the grant date and are settled in shares of common stock.
(2) This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, December 1, 2017.
(3) This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 12, 2018.
(4) This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, March 20, 2020.
(5) This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 9, 2020.
(6) This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 8, 2021.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
Anderson Erik S
250 CAMPUS DRIVE
MARLBOROUGH, MA 01752


Div. Pres., Breast & Skeletal

Signatures
/s/ Mark W. Irving, attorney-in-fact for Mr. Anderson10/21/2022
**Signature of Reporting PersonDate


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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