HOLX Hologic Inc

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person * Mitchell Essex D	2. Date of Event Requiring Statement (MM/DD/YYYY) 10/14/2022	3. Issuer Name and Ticker or Trading Symbol HOLOGIC INC [HOLX]
(Last)        (First)        (Middle) 250 CAMPUS DRIVE	4. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director                          _____ 10% Owner ___X___ Officer (give title below)        _____ Other (specify below) Div. President, GYN Surgical /
(Street) MARLBOROUGH, MA 01752       (City)              (State)              (Zip)	5. If Amendment, Date Original Filed(MM/DD/YYYY)	6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	6196 (1)	D

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Non-qualified Stock Option (Right to Buy)	(2)	11/12/2028	Common Stock	1956	$40.97	D
Non-qualified Stock Option (Right to Buy)	(3)	11/11/2029	Common Stock	4526	$45.61	D
Non-qualified Stock Option (Right to Buy)	(4)	11/9/2030	Common Stock	7505	$68.35	D
Non-qualified Stock Option (Right to Buy)	(5)	11/8/2031	Common Stock	11887	$71.13	D

Explanation of Responses:
(1)	Includes restricted stock unit awards which vest in equal installments on each of the first three anniversaries of the grant date and are settled in shares of common stock.
(2)	This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 12, 2018.
(3)	This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 11, 2019.
(4)	This option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 9, 2020.
(5)	The option to purchase common stock becomes exercisable in equal installments on each of the first four anniversaries of the grant date, November 8, 2021.

Reporting Owners
Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Mitchell Essex D 250 CAMPUS DRIVE MARLBOROUGH, MA 01752			Div. President, GYN Surgical

Signatures
/s/ Mark W. Irving, attorney-in-fact for Mr. Mitchell		10/21/2022
**Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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