DSCM Drugstore.Com, Inc. (MM)

drugstore.com, inc. (Nasdaq:DSCM), a leading online retailer of health, beauty, clinical skincare, and vision products, will announce its financial results for the fourth quarter and fiscal year 2010 during a conference call on Tuesday, February 8, 2011 at 5:00 p.m. ET (2:00 p.m. PT). A press release of the fourth quarter and full year 2010 earnings will be distributed via GlobeNewswire and posted on the drugstore.com(TM) website at www.investor.drugstore.com.

The conference call will also be broadcast live over the Internet, and the audio and financial slides will be accessible through replays for 60 days on the drugstore.com(TM) website at www.investor.drugstore.com, by clicking on the "audio" hyperlink.

About drugstore.com, inc.

drugstore.com, inc. (Nasdaq:DSCM) is a leading online retailer of health, beauty, clinical skincare, and vision products. Our portfolio of brands includes: drugstore.com(TM), Beauty.com(TM), SkinStore.com(TM), and VisionDirect.com(TM). All provide a convenient, private, and informative shopping experience while offering a wide assortment of more than 50,000 nonprescription products at competitive prices.

The drugstore.com pharmacy in partnership with BioScrip Pharmacy Services, Inc. is certified by the National Association of Boards of Pharmacy (NABP) as a Verified Internet Pharmacy Practice Site (VIPPS) and complies with federal and state laws and regulations in the United States.

The drugstore.com, inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=6419

CONTACT: Investor Relations:
         Brinlea Johnson
         212-551-1453
         brinlea@blueshirtgroup.com