As Filed with the Securities and Exchange Commission on January 13, 2011
Registration No. 333-161264
Registration No. 333-147258
Registration No. 333-116662
Registration No. 333-88544
Registration No. 333-59164
Registration No. 333-19465
Registration No. 333-06765
Registration No. 333-06771
Registration No. 03-320188
Registration No. 333-124779
Registration No. 333-110158
Registration No. 03379336
Registration No. 03364466
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-161264
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-147258
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-116662
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-88544
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-59164
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-19465
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-06765
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-8 REGISTRATION STATEMENT NO. 333-06771
POST-EFFECTIVE AMENDMENT NO. 2 TO
FORM S-8 REGISTRATION STATEMENT NO. 03-320188
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-3 REGISTRATION STATEMENT NO. 333-124779
POST-EFFECTIVE AMENDMENT NO. 2 TO
FORM S-3 REGISTRATION STATEMENT NO. 333-110158
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-3 REGISTRATION STATEMENT NO. 03379336
POST-EFFECTIVE AMENDMENT NO. 1 TO
FORM S-3 REGISTRATION STATEMENT NO. 03364466
UNDER THE SECURITIES ACT OF 1933
Cypress Bioscience, Inc.
(Exact name of registrant as specified in its charter)
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Delaware
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22-2389839
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(State or other jurisdiction of
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(I.R.S. Employer Identification No.)
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incorporation or organization)
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4350 Executive Drive, Suite 325
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San Diego, California
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92121
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(Address of Principal Executive Offices)
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(Zip Code)
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Cypress Bioscience, Inc. 2009 Equity Incentive Plan
2000 Equity Incentive Plan, As Amended
Warrant to Purchase Common Stock
Common Stock Purchase Warrants
1996 Equity Incentive Plan
Incentive Stock and Appreciation Plan
1988 Nonqualified Stock Option Plan
Non-Plan Stock Options
(Full Title of the Plans)
Pablo Legorreta
Cypress Bioscience, Inc.
4350 Executive Drive, Suite 325
San Diego, California 92121
(Name and address of agent for service)
Telephone: (858) 452-2323
(Telephone number, including area code, of agent for service)
with copies to:
George W. Lloyd
Goodwin Procter LLP
Exchange Place
Boston, Massachusetts 02109
Telephone: (617) 570-1000
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a
non-accelerated filer, or a smaller reporting company. See the definitions of large accelerated
filer, accelerated filer and smaller reporting company in Rule 12b-2 of the Exchange Act.
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Large accelerated filer
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Accelerated filer
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Non-accelerated filer
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(Do not check if a smaller reporting company)
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Smaller reporting company
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DEREGISTRATION OF SECURITIES
These Post-Effective Amendments relate to the following Registration Statements on Form S-8
and Form S-3 (collectively, the
Registration Statements
) of Cypress Bioscience, Inc. (the
Registrant
):
File No. 333-161264, pertaining to the registration of 8,000,000 shares of the Registrants
common stock, $0.001 par value per share (the
Common Stock
), issuable under the
Registrants Cypress Bioscience, Inc. 2009 Equity Incentive Plan, which was filed with the
Securities and Exchange Commission (the
SEC
) on August 11, 2009;
File No. 333-147258, pertaining to the registration of 5,365,358 shares of Common Stock,
issuable under the Registrants 2000 Equity Incentive Plan, As Amended, which was filed with
the SEC on November 9, 2007;
File No. 333-116662, pertaining to the registration of 4,548,449 shares of Common Stock,
issuable under the Registrants 2000 Equity Incentive Plan, As Amended, which was filed with
the SEC on June 18, 2004;
File No. 333-88544, pertaining to the registration of 1,900,000 shares of Common Stock,
issuable under the Registrants 2000 Equity Incentive Plan, As Amended, which was filed with
the SEC on May 17, 2002;
File No. 333-59164, pertaining to the registration of 562,500 shares of Common Stock,
issuable under the Registrants 2000 Equity Incentive Plan, As Amended, which was filed with
the SEC on April 18, 2001;
File No. 333-19465, pertaining to the registration of 100,000 shares of Common Stock,
issuable under the Registrants Warrant to Purchase Common Stock, which was filed with the
SEC on January 9, 1997. On March 9, 2001, the Registrant conducted a 1-for-8 reverse stock
split, such that this registration statement now covers 12,500 shares of Common Stock
issuable under the Registrants Warrant to Purchase Common Stock;
File No. 333-06765, pertaining to the registration of 334,800 shares of Common Stock,
issuable under the Registrants Common Stock Purchase Warrants, which was filed with the SEC
on June 25, 1996. On March 9, 2001, the Registrant conducted a 1-for-8 reverse stock split,
such that this registration statement now covers 41,850 shares of Common Stock issuable
under the Registrants Warrant to Purchase Common Stock;
File No. 333-06771, pertaining to the registration of 8,806,335 shares of Common Stock,
issuable under the Registrants 1996 Equity Incentive Plan, Incentive Stock Option and
Appreciation Plan, 1998 Nonqualified Stock Option Plan and Non-Plan Stock Options, which was
filed with the SEC on June 25, 1996. On March 9, 2001, the Registrant conducted a 1-for-8
reverse stock split, such that this registration statement now covers 110,080 shares of
Common Stock issuable under the Registrants 1996 Equity Incentive Plan, Incentive Stock
Option and Appreciation Plan, 1998 Nonqualified Stock Option Plan and Non-Plan Stock
Options;
File No. 03-320188, which was filed with the SEC on February 23, 1988, as amended on March
16, 1988.
File No. 333-124779, pertaining to the shelf registration of an indefinite number of
shares of Common Stock, up to a maximum aggregate offering price of $100,000,000, which was
filed with the SEC on May 10, 2005;
File No. 333-110158, pertaining to the shelf registration of an indefinite number of
shares of Common Stock, up to a maximum aggregate offering price of $100,000,000, which was
filed with the SEC on October 31, 2003 and subsequently amended on January 13, 2004;
File No. 03379336, which was filed with the SEC on May 24, 1994;
File No. 03371278, which was filed with the SEC on May 8, 1993;
File No. 03364466, which was filed with the SEC on June 16, 1993.
The Agreement and Plan of Merger (the
Merger Agreement
), dated as of December 14, 2010, by
and among the Registrant, Ramius Value and Opportunity Advisors LLC, a Delaware limited liability
company, Royalty Pharma US Partners, LP, a Delaware limited partnership, Royalty Pharma US Partners
2008, LP, a Delaware limited partnership, RP Investment Corp., a Delaware corporation, and Ramius
V&O Acquisition LLC, a Delaware limited liability company (the
Purchaser
) provides for, among
other things, the merger of a wholly-owned subsidiary of the Purchaser (
Merger Sub
) with and into
the Registrant, with the Registrant continuing as the surviving corporation and a wholly-owned
subsidiary of the Parent. Pursuant to the Merger Agreement, and upon the terms and subject to the
conditions thereof, Merger Sub effected a short form merger (the
Merger
) pursuant to Delaware
law, which became effective on January 13, 2011, and purchased all of the Registrants outstanding
shares of Common Stock (other than shares of Common Stock held by the Purchaser or Merger Sub or
held by the Registrant as treasury shares and shares for which appraisal rights are exercised) for
$6.50 per share in cash (the
Merger Price
), without interest thereon. As a result of the Merger,
each outstanding share of Common Stock (other than shares of Common Stock owned by the Registrant
as treasury stock or by the Purchaser or Merger Sub and shares for which appraisal rights are
exercised) was automatically converted into the right to receive the Merger Price in cash, without
interest thereon.
In connection with the closing of the Merger, the offerings pursuant to the Registration
Statements have been terminated. In accordance with undertakings made by the Registrant in the
Registration Statements to remove from registration, by means of post-effective amendments, any of
the securities that remain unsold at the termination of the offerings, the Registrant hereby
removes from registration the shares of Common Stock registered but not sold under the Registration
Statements.