Actualisé: Transgene Buys European Rights On Jennerex Cancer Drug
September 08 2010 - 9:16AM
Bourse Web Dow Jones (French)
(Adds details and company comment.)
In an unusual move for a small biotechnology company, Transgene
SA (TNG.FR) Wednesday acquired the European rights to develop and
sell a cancer drug with blockbuster potential from another research
company, San Francisco-based biotech group Jennerex.
Transgene shares jumped nearly 6% on the news.
Jennerex is a privately held developer of drugs, while Transgene is
a part the French Merieux family holding, that also owns the
diagnosis specialist bioMerieux SA (BIM.FR).
While biotech companies usually license their drugs to big pharma
groups with deep pockets and a track record of launching successful
new products, this partnership combines two small research
companies with little revenue and which have yet to bring their
first drugs to the market.
"It's quite exceptional, this is not the way business is usually
done in the industry," Transgene Chief Executive Philippe Archinard
said during a conference call with reporters.
But Transgene's knowledge in the field of cancer studies and its
ties with the Merieux conglomerate "convinced Jennerex that we
would be the most competent for this project," Archinard added.
The experimental drug, known as JX-594, has still to enter late
stage Phase-3 clinical trials, But it has shown anti-cancer and
well-tolerated safety properties, notably when applied to liver
tumors, Transgene said.
The drug is designed to compete with U.S. pharma giant Bayer Inc.'s
Nexavar, which Archinard said has over $800 million in annual
European sales in a market with substantial medical needs.
"The first data (on JX-594) are very promising and superior to
Nexavar's performance; but they still have to be confirmed by
further studies," Archinard told Dow Jones Newswires in a telephone
interview. He didn't elaborate.
Transgene agreed to pay up to $116 million to Jennerex for the
JX-594 rights in Europe, the countries of the former Soviet Union
and in the Middle East. It will also take a minority stake in its
new U.S. partner for about $5 million. And it will fund some
clinical studies related to the drug and give back to Jennerex an
unspecified share of the JX-594 sales in those regions.
Transgene plans to launch a first Phase-3 trial of JX-594 in 2012
and apply for the drug's registration in Europe in 2014, with
possible commercialization in 2015.
At 1230 GMT, Transgene shares were up 5.9%, or EUR0.84, a share
from the previous close to EUR15.20 on the Euronext Paris
exchange.
-Thomas Varela, Dow Jones Newswires; thomas.varela@dowjones.com;
+331 40 17 17 72;
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