RNS Number:0699S
Alexon Group PLC
14 November 2003

                           SCHEDULE 10
 
             NOTIFICATION OF MAJOR INTERESTS IN SHARES


1)   NAME OF COMPANY

     ALEXON GROUP PLC


2)   NAME OF SHAREHOLDER HAVING A MAJOR INTEREST

     CAPITAL GROUP


3)   Please state whether notification indicates that it is in respect of 
     holding of the Shareholder named in 2 above or in respect of a 
     non-beneficial interest or in the case of an individual holder if it is a
     holding of that person's spouse or children under the age of 18

     


4)   Name of the registered holder(s) and, if more than one holder, the 
     number of shares held by each of them.

     SEE BELOW


5)   Number of shares/amount of stock acquired.

     

6)   Percentage of issued Class



7)   Number of shares/amount of stock disposed



8)   Percentage of issued Class



9)   Class of security

     ORD 10P SHARES



10)  Date of transaction




11)  Date company informed

     13/11/03


12)  Total holding following this notification

     2,662,625

               
13)  Total percentage holding of issued class following this notification

     4.302%


14)  Any additional information




15)  Name of contact and telephone number for queries

     R PIGGOTT
     01582 723131


16)  Name and signature of authorised company official responsible for 
     making this notification


     Date of Notification     14 NOVEMBER 2003


LETTER TO:  ALEXON GROUP PLC

SECTION 198 NOTIFICATION 

Notification of Increase

This Notice is given by The Capital Group Companies. Inc. on behalf of its
affiliates, including Capital International SA, Capital International Limited,
Capital International, Inc., and Capital Guardian Trust Company, pursuant to
Section  198 of the Companies Act 1985.

The interest in the relevant share capital indicated below arises by virtue of
holdings attributed to the Companies (see Schedule A). These holdings form part
of funds managed on behalf of investment clients by the Companies.

Share capital to which this relates:

Ordinary Shares (61,893,001 shares outstanding) 

Number of shares in which the Companies have an interest;

2,662,625 

Name(s) of registered holder(s);

See Schedule B


As of 11 November 2003 

Alexon Group plc
 
                                               Number of Shares       Percent of
                                                                     Outstanding

The Capital Group Companies. Inc. ("CG") holdings   2,662,625          4.302%

Holdings by CG Management Companies and Funds:

-   Capital Guardian Trust Company                  2,200,928          3.556%

-   Capital International Limited                     331,447          0.536%

-   Capital International S.A.                         40,191          0.065%

-   Capital International, Inc.                        90,059          0.146%


Schedule A


Schedule of holdings in Alexon Group plc 

As of 11 November 2003

Capital Guardian Trust Company
 

Registered Name                                                     Local Shares 

State Street Nominees Limited                                             9,452

Chase Nominees Limited                                                 1,900,131

Midland Bank plc                                                         195,638

Nortrust Nominees                                                         95,707

                                              TOTAL                    2,200,928


Schedule B

Capital International Limited

Registered Name                                                     Local Shares

Chase Nominees Limited                                                   331,447

                                              TOTAL                      331,447

Schedule B

Capital International S.A.
 
Registered Name                                                     Local Shares

Citibank London                                                           40,191

                                              TOTAL                       40,191

Schedule B

Capital International Inc.
 
Registered Name                                                     Local Shares 

State Street Nominees                                                     27,842

Chase Nominees Limited                                                    62,217

                                              TOTAL                       90,059

Schedule B

                      This information is provided by RNS
            The company news service from the London Stock Exchange

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