AET Aetna Inc. (delisted)

CUSIP NO. 00817Y108 13G PAGE 2 OF 6 PAGES

1. NAME OF REPORTING PERSON: STATE STREET CORPORATION
 I.R.S. IDENTIFICATION NO. OF ABOVE PERSON: 04-2456637


2. CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP

 NOT APPLICABLE A __

 B __
3. SEC USE ONLY

4. CITIZENSHIP OR PLACE OF ORGANIZATION

 BOSTON, MASSACHUSETTS

5. SOLE VOTING POWER
 0 SHARES
6. SHARED VOTING POWER
 24,542,539 SHARES
7. SOLE DISPOSITIVE POWER
 0 SHARES
8. SHARED DISPOSITIVE POWER
 24,542,539 SHARES
9. AGGREGATED AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
 24,542,539 SHARES

10. CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
 SHARES

 NOT APPLICABLE

11. PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9

 6.1%

12. TYPE OF REPORTING PERSON

 HC













CUSIP NO. 00817Y108 13G PAGE 3 OF 6 PAGES

ITEM 1.

 (A) NAME OF ISSUER

 AETNA, INC

 (B) ADDRESS OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES

 151 FARMINGTON AVENUE
 HARTFORD CT 06156

ITEM 2.

 (A) NAME OF PERSON FILING

 STATE STREET CORPORATION AND ANY OTHER REPORTING PERSON
 IDENTIFIED ON THE SECOND PART OF THE COVER PAGES HERETO

 (B) ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE,
 RESIDENCE

 STATE STREET FINANCIAL CENTER
 ONE LINCOLN STREET
 BOSTON, MA 02111
 (FOR ALL REPORTING PERSONS)

 (C) CITIZENSHIP: SEE ITEM 4 (CITIZENSSHIP OR PLACE OF
 ORGANIZATION) OF COVER PAGES

 (D) TITLE OF CLASS OF SECURITIES

 COMMON STOCK, $0.01 PAR VALUE PER SHARE

 (E) CUSIP NUMBER:

 00817Y108

ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B), OR
 13D-2(B), OR (C), CHECK WHETHER THE PERSON FILING IS A:

 SEE ITEM 12(TYPE OF REPORTING PERSON) OF THE COVER PAGE
 FOR EACH REPORTING PERSON AND THE TABLE BELOW, WHICH EXPLAINS
 THE MEANING OF THE TWO LETTER SYMBOLS APPEARING IN ITEM 12 OF
 THE COVER PAGES.

 SYMBOL CATEGORY

 BK BANK AS DEFINED IN SECTION 3(A)(6) OF THE ACT.
 IC INSURANCE COMPANY AS DEFINED IN SECTION 3 (A)(19)
 OF THE ACT.


CUSIP NO. 00817Y108 13G PAGE 4 OF 6 PAGES

 IC INVESTMENT COMPANY REGISTERED UNDER SECTION 8 OF
 THE INVESTMENT COMPANY ACT OF 1940.
 IA AN INVESTMENT ADVISER IN ACCORDANCE WITH RULE
 13D-1(B)(1)(II)(E).
 EP AN EMPLOYEE BENEFIT PLAN OR ENDOWMENT FUND IN
 ACCORDANCE WITH RULE 13D-1(B)(1)(II)(F).
 HC A PARENT HOLDING COMPANY OR CONTROL PERSON IN
 ACCORDANCE WITH RULE 13D-1(B)(1)(II)(G).
 SA A SAVINGS ASSOCIATIONS AS DEFINED IN SECTION 3(B)
 OF THE FEDERAL DEPOSIT INSURANCE ACT (12 U.S.C.
 1813).
 CP A CHURCH PLAN THAT IS EXCLUDED FROM THE DEFINITION
 OF AN INVESTMENT COMPANY UNDER SECTION 3(C)(14)OF
 THE INVESTMENT COMPANY ACT OF 1940.

ITEM 4. OWNERSHIP

 THE INFORMATION SET FORTH IN ROWS 5 THROUGH 11 OF THE COVER
 PAGE HERETO FOR EACH OF THE REPORTING PERSONS IS INCORPORATED
 HEREIN BY REFERENCE. THE PERCENTAGE AMOUNT SET FORTH IN ROW
 11 FOR ALL COVER PAGES FILED HEREWITH IS CALCULATED BASED
 UPON THE 400,100,000 SHARES OF COMMON STOCK ISSUED AND
 OUTSTANDING AS REPORTED BY AETNA,INC IN ITS FORM 10-Q FOR THE
 QUARTERLY PERIOD ENDED SEPTEMBER 30, 2010.

 THIS REPORT IS NOT AN ADMISSION THAT ANY OF THE REPORTING
 PERSONS IS THE BENEFICIAL OWNER OF ANY SECURITIES COVERED BY
 THIS REPORT, AND THE REPORTING PERSONS EXPRESSLY DISCLAIM
 BENEFICIAL OWNERSHIP OF ALL SHARES PURSUANT TO RULE 13D-4,
 EXCEPT IN THEIR FIDUCIARY CAPACITY UNDER ERISA.

ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS

 NOT APPLICABLE

ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER
 PERSON.

 NOT APPLICABLE













CUSIP NO. 00817Y108 13G PAGE 5 OF 6 PAGES

ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH
 ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING
 COMPANY OR CONTROL PERSON

 SEE EXHIBIT 1 ATTACHED HERETO

ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP

 NOT APPLICABLE

ITEM 9. NOTICE OF DISSOLUTION OF GROUP

 NOT APPLICABLE

ITEM 10. CERTIFICATION

 BY SIGNING BELOW I CERTIFY THAT, TO THE BEST OF MY
KNOWLEDGE AND BELIEF, THE SECURITIES REFERRED TO ABOVE WERE
ACQUIRED AND ARE HELD IN THE ORDINARY COURSE OF BUSINESS AND WERE NOT
ACQUIRED AND ARE NOT HELD FOR THE PURPOSE OR WITH THE EFFECT OF
CHANGING OR INFLUENCING THE CONTROL OF THE ISSUER OF THE SECURITIES AND
WERE NOT ACQUIRED AND ARE NOT HELD IN CONNECTION WITH OR AS A
PARTICIPANT IN ANY TRANSACTION HAVING THAT PURPOSE OR EFFECT.

 SIGNATURES


 AFTER REASONABLE INQUIRY AND TO THE BEST OF HIS KNOWLEDGE AND
BELIEF, EACH OF THE UNDERSIGNED CERTIFIES THAT THE INFORMATION SET
FORTH IN THIS STATEMENT IS TRUE, COMPLETE AND CORRECT.

 10 FEBRUARY 2011
 STATE STREET CORPORATION



 /s/ JAMES J. MALERBA
 EXECUTIVE VICE PRESIDENT,
 CORPORATE CONTROLLER









CUSIP NO. 00817Y108 13G PAGE 6 OF 6 PAGES




 EXHIBIT 1


 THE FOLLOWING TABLE LISTS THE IDENTITY AND ITEM 3 CLASSIFICATION
OF EACH SUBSIDIARY OF STATE STREET CORPORATION, THE PARENT HOLDING
COMPANY, THAT BENEFICIALLY OWNS THE ISSUER'S COMMON STOCK. PLEASE REFER
TO ITEM 3 OF THE ATTACHED SCHEDULE 13G FOR A DESCRIPTION OF EACH OF THE
TWO-LETTER SYMBOLS REPRESENTING THE ITEM 3 CLASSIFICATION BELOW.

SUBSIDIARY ITEM 3 CLASSIFICATION
STATE STREET BANK AND TRUST COMPANY BK
SSGA FUNDS MANAGEMENT, INC IA
STATE STREET GLOBAL ADVISORS LIMITED IA
STATE STREET GLOBAL ADVISORS LTD. IA
STATE STREET GLOBAL ADVISORS FRANCE S.A. IA
STATE STREET GLOBAL ADVISORS AUSTRALIA LIMITED IA
STATE STREET GLOBAL ADVISORS JAPAN CO., LTD. IA
STATE STREET GLOBAL ADVISORS ASIA LIMITED IA



NOTE: ALL OF THE LEGAL ENTITIES ABOVE ARE DIRECT OR INDIRECT
SUBSIDIARIES OF STATE STREET CORPORATION.