RNS Number:8392R
ISIS Asset Management PLC
07 November 2003

To: London Stock Exchange

Attention: RNS

Date: 7 November 2003

From: ISIS Asset Management plc (the "Company")




Notification of interests of directors and connected persons


Monthly investment in the ISIS Asset Management plc Share Incentive Plan ("SIP")


On 7 November 2003, the trustees (the "Trustees") of the SIP acquired a total of
4,775 ordinary shares of 0.1 pence each in the Company (the "Shares") at a price
of 246.50 pence per Share.


The Company has today received notification from Messrs Carter, Arthur, Back,
Criticos, Paterson Brown and Talbut that, as executive directors of the Company,
they have an interest in the Shares held in trust under the Scheme.


The Company has also today received notification from Messrs Carter, Arthur,
Back, Criticos and Paterson Brown that of the 4,775 Shares acquired by the
Trustees, 51 Shares each (a total of 255 Shares) were acquired on their behalf
as partnership shares under the SIP.


The SIP is an Inland Revenue approved Share Incentive Plan.











                      This information is provided by RNS
            The company news service from the London Stock Exchange
END

RDSQDLFBXFBLFBB