TIDMINS

RNS Number : 1324U

Instem plc

05 April 2016

Instem plc

("Instem", the "Company" or the "Group")

Unaudited Full Year Results

Instem (AIM: INS.L), a leading provider of IT solutions to the global early development healthcare market, announces its unaudited full year results for the 12 months ended 31 December 2015.

Financial Highlights:

   --     Revenues increased 22% to GBP16.3m (2014: GBP13.4m) 

o Recurring revenues increased 9% to GBP10.0m (2014: GBP9.2m)

o Software as a Service (SaaS) revenues increased 14% to GBP2.1m (2014: GBP1.8m)

   --     EBITDA* increased 43% to GBP2.5m (2014: GBP1.7m) 
   --     Adjusted** profit before tax of GBP1.7m (2014: GBP1.1m) 
   --     Loss before tax of GBP0.4m (2014: profit GBP0.2m) 

o After charging GBP1.4m of previously announced deferred contingent consideration (2014: GBPnil)

   --     Adjusted** basic earnings per share of 13.3p (2014: 8.4p) 
   --     Adjusted** fully diluted earnings per share of 12.9p (2014: 8.3p) 
   --     Net cash balance as at 31 December 2015 of GBP2.2m (2014: GBP1.7m) 

o After paying GBP1.3m of deferred contingent consideration (2014: GBP0.3m)

*Earnings before interest, tax, depreciation, amortisation and non-recurring costs.

**After adjusting for the effect of foreign currency exchange on the revaluation of inter-company balances included in finance income/(costs), non-recurring items and amortisation of intangibles on acquisitions. Profit is adjusted in this way to provide a clearer measure of underlying operating performance.

Operational Highlights:

-- Final deferred contingent consideration was paid for Perceptive Instruments and agreed early for Instem Clinical (formerly Logos Technologies) after both exceeded performance criteria.

-- Significant ALPHADAS Contract wins included three announced in May 2015 worth approximately GBP1.4 million.

   --     Won the majority of SEND business placed worldwide. 
   --     Instem Japan incorporated and Tokyo office opened. 

Post Balance Sheet Event

In February 2016 the Company announced it had raised GBP5.0 million (before expenses) by way of a placing of 2,500,000 New Ordinary Shares, at a price of 200 pence per ordinary share, with certain new and existing investors. The net proceeds are intended to be used in the near term primarily to fund growth through acquisition and also for working capital to enhance organic growth.

Phil Reason, CEO of Instem plc, commented:

"Our core addressable markets continue to grow in terms of the number of potential customers and the absolute size. Our products and services recorded significant year-on-year revenue growth during 2015 and we are pleased to report that we entered the new financial year with a strong forward order book. Regulatory requirements and the enlarged drug R&D pipeline are expected to continue to stimulate demand for Instem's solutions and services.

The recently strengthened balance sheet provides opportunities to invest further in our core products and services, accelerate the development of new offerings such as KnowledgeScan and SEND submit(TM) and play a significant role in consolidating the industry in which we operate.

We therefore look forward to the coming year with confidence and expect to deliver further operational and financial progress."

 
 For further information, please 
  contact: 
 Instem plc                              +44 (0) 1785 825 600 
 Phil Reason, Chief Executive Officer 
 Nigel Goldsmith, Chief Financial 
  Officer 
 
 N+1 Singer (Nominated Adviser 
  & Broker)                              +44 (0) 207 496 3000 
 Richard Lindley 
 Nick Owen 
 James White 
 
 Walbrook Financial PR                   +44 (0) 207 933 8780 
 Paul Cornelius 
 Helen Cresswell 
 Sam Allen 
 Paul Whittington 
 

About Instem

Instem is a leading supplier of IT applications to the early development healthcare market, delivering compelling solutions for data collection, management and analysis across the R&D continuum. Instem applications are in use by customers worldwide, meeting the rapidly expanding needs of life science and healthcare organisations for data-driven decision making leading to safer, more effective products.

Instem's portfolio of software solutions increases client productivity by automating study-related processes while offering the unique ability to generate new knowledge through the extraction and harmonisation of actionable scientific information.

Instem supports over 450 clients through full service offices in the United States, the United Kingdom, India, China and Japan, with additional presence in France.

To learn more about Instem solutions and its mission, please visit www.instem.com

Chairman's Statement

The positive market dynamics experienced at the end of 2014 continued throughout the year, providing an encouraging backdrop for the development of the Group. I am, therefore, pleased to be able to report that all areas of business achieved successful outcomes for the year.

Consequently, not only has the Group increased revenue and underlying profits during the year, but we are also increasingly optimistic about 2016.

We have maintained our pre-eminent position in the preclinical market whilst also winning the majority of business placed globally in the early clinical market.

A highlight of the year was the market leadership demonstrated by our team offering Standard for the Exchange of Non-clinical Data (SEND) software and services: where we once again secured the majority of business placed during 2015. This was particularly important following the announcement from the US Food & Drug Administration ("FDA") mandating SEND at the end of 2014.

A cornerstone of our global leadership strategy for each of our product lines is to ensure that we are able to provide sales and service facilities locally wherever there are substantial groupings of customers. Consequently, we opened an office in Tokyo, Japan, complementing existing Instem Asian locations in Pune, India and Shanghai, China. We expect the Instem Japan facility to start to contribute to our revenues during 2016.

At a corporate level we were pleased to make the final payment for the Perceptive Instruments' acquisition as a result of it exceeding our targets. Further, in December 2015, we announced the early agreement of the Instem Clinical (formerly Logos Technologies) earn-out. Given this business had out-performed in each of its prior earn out years, the Board determined that in order to maximise its potential it was appropriate to fully align the objectives of both its shareholders, who include key managers in the business and the Group.

Following the end of the financial year, in February 2016 the Company announced it had raised GBP5.0 million (before expenses) by way of a placing of 2,500,000 New Ordinary Shares with new and existing investors. The Board intends to use the proceeds of this placing, along with existing cash resources, to continue the Group's acquisition strategy and to provide additional working capital. We believe that having the funding in place will be of significant benefit for the execution of this strategy, as a result of providing certainty to potential vendors during the negotiation of deal terms.

Finally, I would like to take this opportunity once again to thank all of our staff, customers and partners for their ongoing support.

David Gare, Non-Executive Chairman

4 April 2016

Chief Executive's Statement

The twelve months to 31 December 2015 represented another year of significant financial and operational progress across the Group.

The year began with a record order book and a strengthening market backdrop. This was converted into revenue through successful contract execution, supplemented by winning and delivering new business contracts throughout the year.

Notably in 2015, both our clinical and preclinical products and services gained traction, as a result of record numbers of compounds progressing through the early stages of the drug development pipeline. Our laboratory workflow automation solutions were selected to deliver efficiencies, replacing "paper" records, legacy in-house applications or ageing commercial systems. Further, new regulatory requirements also drove the adoption of Instem's technology. Once again, there was a blend of perpetual license sales and operationally effective SaaS deployments, with recurring revenue growing in absolute terms year-on-year. This provides the business with increased revenue visibility and long-term stability.

Importantly for the Group as a whole, the growth experienced in the preclinical market during 2014 now appears to be flowing through into increased activity levels within the early clinical phase of drug development. Consequently, ALPHADAS, the Group's leading early phase clinical software platform, generated record levels of new business.

The Group continues to attract some of the most capable people in the industry, appointing senior new hires within the SEND business and establishing an office in Tokyo, Japan. This office will support distributors and customers across the region.

Operational Review

All areas of the Group are now taking advantage of Instem's global operations with marketing, sales, service delivery and client support now available through offices in the UK, North America, China, India and Japan. Although the Group has operated successfully in Japan through local distributors, establishing an Instem presence is expected to increase demand, in what is the second highest spending nation in the world on pharmaceutical research and development.

The Group's Pune, India operation has moved into much larger premises to accommodate the further expansion of software development, back office services and, increasingly, client related service delivery activities. Pune enjoys a reputation for academic excellence and is one of India's most attractive cities in which to live; enabling us to secure both local talent and exceptional candidates from other areas of the country.

(MORE TO FOLLOW) Dow Jones Newswires

April 05, 2016 02:00 ET (06:00 GMT)

Preclinical - Provantis(R) & Perceptive Instruments

Opportunities for Provantis and Perceptive Instruments solutions within the preclinical market continued to increase during the year as study volumes, mostly carried out by Contract Research Organisations (CROs), accelerated. The Group's "best-of-breed" products increased their share of the preclinical market as customers sought to leverage additional modules and new software features with both new and existing clients increasingly adopting operationally effective SaaS based deployments.

Provantis, the Group's primary preclinical software suite, continued to win licence sales across the Group's client base with continued displacement of legacy in-house systems as new implementation projects progressed during the year. By the end of the first half of 2015, all the Group's US-based SaaS customers were running the latest product versions, enabling us to achieve higher quality support and increased effectiveness of our delivery infrastructure.

Perceptive Instruments ("Perceptive") continued to perform strongly as part of an enlarged business. In particular, Perceptive had success in up-selling higher value modules, such as AMES study manager and Cyto Study Manager, into existing Instem clients. During the year, due to the strong financial performance of Perceptive for the period to November 2014, the Group paid the vendors the maximum consideration for the acquisition, in accordance with the original acquisition agreement.

Perceptive is located in Suffolk, UK, and develops, manufactures and supplies software and hardware products for in-vitro study management and data collection in the genetic toxicology, microbiology and immunology markets. Perceptive is the leading technology provider within its niche market and there are few competitors, of any scale, active in the space.

Early Stage Clinical - ALPHADAS(TM)

Our ALPHADAS early phase clinical software solution performed particularly well during 2015. We added five new clients across mainland Europe, Canada and the USA and additional sites/users for existing clients. New releases of ALPHADAS have been widely implemented by existing customers, delivering important new capabilities and enticing clients to adopt further modules from the product suite.

Instem entered the early phase clinical market in 2013 with the acquisition of Logos Technologies, now Instem Clinical, and its product suite ALPHADAS. Since the acquisition, ALPHADAS revenues have grown strongly and it is now a core offering of the Group.

Instem Scientific

The transition of Instem Scientific, from a software products business to an 'outcome-led' managed service, continued during the year, with further investment in "KnowledgeScan". KnowledgeScan allows our specialist investigators to provide rigorous insight into potential and observed issues during all stages of new compound development, by combining powerful information technology with transparent, systematic and comprehensive analytical workflows. The service leverages the Group's powerful big-data technology assets and is designed to monitise the Group's expertise across its extensive scientific content, ontologies and vocabularies, which have been developed over multiple projects during the last 10 years.

We believe this outcome-led service fits well with the ongoing restructuring across the pharmaceutical industry, which has led to a significant increase in R&D outsourcing. Whilst the financial benefits of Instem Scientific may not be felt by the wider Group immediately, pilot KnowledgeScan projects have progressed extremely well during the year and keep Instem at the leading edge of this field of development.

Electronic Regulatory Submissions (SEND) - submit(TM)

As highlighted in the half-year statement, the new business pipeline for both our software solutions and SEND ("Standard for the Exchange of Non-clinical Data") data set conversion services continued to increase month-on-month during the year as the new electronic regulatory submission standard started to become mandatory in our client community.

Pleasingly, Instem continued to secure the overwhelming majority of all new business placed in this area, converting some of this into revenue in 2015 with the balance contributing to the strong opening order backlog for 2015. We continue to believe that Instem's submit(TM) software suite offers the most advanced product to meet the requirements of the SEND standard.

As a direct consequence of the increased demand for SEND, the Group further strengthened the submit(TM) development, sales and implementation teams during the year. In particular, two highly experienced market facing consultants were hired, both of whom have been key members on the SEND committee for over 10 years. We expect these consultants to gain further traction for submit(TM) during 2016 and beyond.

Market Overview

Citeline(R), which claims to have the world's most comprehensive source of real-time R&D intelligence for the pharmaceutical industry, recently reported that the global drug pipeline had increased by 11.5% in the past year with an additional 1,418 drugs added to the pipeline (993 were added in the previous year). The total number of companies with one or more drugs in the regulatory stages of development has now risen to 3,687, an increase of 12.2% on the previous year. This is the biggest increase ever in terms of numbers of companies and the second largest percentage-wise.

Following the record growth recorded in 2014, 2015 again represented the largest annual drug pipeline rise on record, in absolute terms, and there is further evidence that the global pharmaceutical market is still moving resources from late stage clinical development into early stage candidates in order to refill the R&D pipeline.

These drug development activities require specialist services and technologies, with a particular focus on IT solutions, which enable organisations to reduce timelines, improve cost efficiencies and ensure they are able to meet ever-increasing regulatory demands.

Preclinical market

The 2016 pipeline shows increases at all phases of development, but the preclinical phase shows the largest rise, with the number of projects up by 13.2% as shown in the recent Citeline(R) report.

With increased preclinical study volume helping to create opportunities with their pharma sponsors, preclinical CROs continue to report strong demand in North America and increased demand in Europe and Japan in comparison with 2014. Consequently, numerous CROs have been adding or looking to add additional capacity organically or through acquisition. On 7(th) January 2016 Charles River Laboratories announced its intention to acquire WIL Research and public announcements have talked of continued growth and expansion following completion of the transaction. Both of these large CROs are heavily committed Instem clients and we expect the impact of the merger on Instem will become clearer during 2016.

Early Stage Clinical market

The Citeline(R) report details significant growth in the clinical stage of drug development, with 2015 posting the largest increases in this decade in both Phase I (up by 190 drugs/11.4%) and Phase III (up by 146 drugs/18.1%). The growth rate in Phase II slowed but is still at record levels (up by 110 drugs/5.1%). The Phase III figure is particularly encouraging, not just because it is showing significant growth, but also as these are the drugs which should be feeding into the new release schedule for 2017 and 2018.

Opportunities continue to exist within the early stage clinical market for the deployment of Instem's software solutions. These opportunities are resulting from an increasing recognition of the need to control data quality and integrity and because levels of automation within the early stage environment remain relatively modest.

Send

The regulatory bodies' preference for the electronic capture, storage and transfer of data for new drug submissions continues to grow and pharmaceutical organisations are seeking tools that can help them to prioritise suitable drug candidates utilising vast volumes of historic data, in addition to managing their compliance risk with the authorities. SEND was developed to speed up and enhance the review process for drug applications by developing electronic tools to analyse and visualise these submissions, and building data warehouses to rapidly query data across drugs, companies, and clinical and non-clinical disciplines.

As a result, the US Food & Drug Administration has made it mandatory to use SEND for all related study submissions, starting with those run after December 2016 that support the submission of a new drug application. The Directors believe that the annual total market spend on technology and services in respect of SEND will grow to approximately $150 million in 2019 and we are looking to optimise Instem's offering to all areas of this market.

Government and Academic Research

Funding for Government/Academic institutions undertaking later stages of life sciences research in North America, China and Europe continues to grow to cover gaps that are not sufficiently attractive to commercial enterprises. This enables them to invest in both study automation solutions and in innovative approaches to the process of R&D using novel scientific, informatics and big data approaches, providing another source of revenue for the majority of Instem's solutions and services.

Financial Review

Instem's revenue model consists of perpetual licence income with annual support contracts, professional services fees and SaaS subscriptions. Total revenue for the twelve months to 31 December 2015 increased 22% to GBP16.3m compared with last year. Demand for our products and services from customers in all territories in which we operate continued to increase, reflecting increased levels of pharmaceutical R&D activity.

Revenue growth during the year came from both new and existing customers and was driven primarily from increases in Provantis and ALPHADAS related business.

(MORE TO FOLLOW) Dow Jones Newswires

April 05, 2016 02:00 ET (06:00 GMT)

Total recurring revenue, from support contracts and SaaS based subscriptions, increased 9% during the year to GBP10.0m (2014: GBP9.2m), representing 62% of total revenue. SaaS based revenue increased by 14% to GBP2.1m (2014: GBP1.8m).

Earnings before interest, tax, depreciation and amortisation increased 43% for the year to GBP2.5m. (2014: GBP1.7m). Development costs incurred during the year were GBP1.9m (2014: GBP1.3m), of which GBP0.6m (2014: GBP0.3m) was capitalised.

Adjusted profit before tax (i.e. adjusting for the effect of foreign currency exchange on the revaluation of inter-company balances included in finance income/ (costs), non-recurring items and amortisation of intangibles on acquisitions) was GBP1.7m (2014: GBP1.1m). The non-recurring charge of GBP1.4m, which was previously announced, arose following the early agreement of the final deferred contingent consideration payment relating to the 2013 Instem Clinical (formerly Logos Technologies) acquisition after all profit targets were exceeded. This resulted in a total consideration payment for the Logos business totalling GBP4.8m, in a mixture of cash and shares, slightly lower than the potential maximum payable of GBP5.0m. The total paid up until the end of 2015 was GBP4.1m, with the remaining balance of GBP0.7m to be paid in cash in two equal instalments in July 2016 and July 2017.

The Group claimed and received research and development tax credits during the year of GBP0.2m (2014: GBP0.1m).

Basic and fully diluted earnings per share calculated on an adjusted basis were ahead of the prior year by 58% and 55% respectively.

Net cash generated from operations was GBP2.5m (2014: GBP0.5m). The Group had net cash reserves of GBP2.2m at 31 December 2015, compared with GBP1.7m as at 31 December 2014, after making deferred contingent consideration cash payments for the 2013 Instem Clinical acquisition amounting to GBP0.7m and one deferred contingent consideration payment in respect of the 2013 Perceptive Instruments acquisition of GBP0.3m. In addition, a cash payment amounting to GBP0.3m was made to repay a Loan Note associated with the Instem Clinincal acquisition. In line with our current policy of retaining cash within the business to capitalise on the available growth opportunities, the Board has not recommended the payment of a dividend.

The Group's legacy defined benefit pension scheme closed to new members in 2000 and to future accrual in 2008. It experienced an increase in the funding deficit during the year calculated in accordance with the provisions of IAS19 that amounted to GBP0.3m (net of deferred tax). This is a non-cash charge and was recognised in Other Comprehensive Income/(Expense). The overall deficit at the year-end stood at GBP3.9m, represented by a fair value of assets of GBP7.8m and a present value of funded obligations of GBP11.7m. As part of the scheme's triennial actuarial valuation as at 5 April 2014, the Group agreed in June 2015 a schedule of payments to the scheme designed to eliminate the funding deficit by November 2023. This involves an increase of GBP0.1m in the Group's current payments to the scheme rising from GBP0.4m to approximately GBP0.5m per annum from April 2016.

Post Balance Sheet Event

As described in the Chairman's statement, following the post year-end fund raising exercise, the Company received GBP5.0m before expenses to support organic growth and acquisition opportunities. The impact of the net funds received will be reported with the 2016 interim results.

Principal risks and uncertainties

The principal risks and uncertainties remain unchanged from those described in our 2014 Annual Report.

Outlook

Our core addressable markets continue to grow in terms of the number of potential customers and the absolute size. Our products and services recorded significant year-on-year revenue growth during 2015 and we are pleased to report that we entered the new financial year with a strong forward order book. Regulatory requirements and the enlarged drug R&D pipeline are expected to continue to stimulate demand for Instem's solutions and services.

The recently strengthened balance sheet provides opportunities to invest further in our core products and services, accelerate the development of new offerings such as KnowledgeScan and SEND submit(TM) and play a significant role in consolidating the industry in which we operate.

We therefore look forward to the coming year with confidence and expect to deliver further operational and financial progress.

Phil Reason

Chief Executive

4 April 2016

Consolidated Statement of Comprehensive Income

For the year ended 31 December 2015

 
                                                                          Note           Unaudited             Audited 
                                                                                        Year ended          Year ended 
   Continuing Operations                                                          31 December 2015    31 December 2014 
                                                                                            GBP000              GBP000 
 REVENUE                                                                     2              16,321              13,429 
 Operating expenses                                                                       (13,553)            (11,572) 
 Share based payment                                                                         (263)               (108) 
 
 EARNINGS BEFORE INTEREST, TAXATION, DEPRECIATION, AMORTISATION AND 
  NON-RECURRING COSTS ('EBITDA')                                                             2,505               1,749 
 
 Depreciation                                                                                (156)               (127) 
 Amortisation of intangibles arising on acquisition                                          (640)               (640) 
 Amortisation of internally generated intangibles                                            (376)               (297) 
 
 PROFIT BEFORE NON-RECURRING COSTS                                                           1,333                 685 
 Non-recurring costs                                                         4             (1,426)               (123) 
 
 (LOSS)/PROFIT FROM OPERATIONS                                                                (93)                 562 
 
 Finance income                                                                                  4                   9 
 Finance costs                                                                               (272)               (359) 
 
 (LOSS)/PROFIT BEFORE TAXATION                                                               (361)                 212 
 Taxation                                                                    3                (67)                (62) 
 
 (LOSS)/PROFIT FOR THE YEAR                                                                  (428)                 150 
 
 OTHER COMPREHENSIVE (EXPENSE)/INCOME 
 Items that will not be reclassified to profit and loss account 
 Actuarial loss on retirement benefit obligations                                            (339)               (621) 
 Deferred tax on actuarial loss                                                                 61                 124 
 
                                                                                             (278)               (497) 
 Items that may be reclassified to profit and loss account 
 Exchange differences on translating foreign operations                                       (24)                  34 
 
 OTHER COMPREHENSIVE EXPENSE FOR THE YEAR                                                    (302)               (463) 
 
 
 TOTAL COMPREHENSIVE EXPENSE FOR THE YEAR                                                    (730)               (313) 
 
 
 (LOSS)/PROFIT ATTRIBUTABLE TO OWNERS OF THE PARENT COMPANY                                  (428)                 150 
 
 TOTAL COMPREHENSIVE EXPENSE ATTRIBUTABLE TO OWNERS OF THE PARENT 
  COMPANY                                                                                    (730)               (313) 
 
 Earnings per share from continuing operations 
 Basic                                                                       5              (3.5)p                1.2p 
 Diluted                                                                     5              (3.5)p                1.2p 
 

Consolidated Statement of Financial Position

As at 31 December 2015

 
                                             Unaudited               Audited 
                                      31 December 2015      31 December 2014 
 ASSETS                              GBP000     GBP000     GBP000     GBP000 
 NON-CURRENT ASSETS 
 Intangible assets                   12,035                12,439 
 Property, plant and equipment          376                   263 
 Deferred tax assets                    663                   574 
 
 TOTAL NON-CURRENT ASSETS                      13,074                 13,276 
 
 CURRENT ASSETS 
 Inventories                            822                   506 
 Trade and other receivables          4,745                 4,432 
 Cash and cash equivalents            2,183                 1,676 
 
 TOTAL CURRENT ASSETS                          7,750                   6,614 
 
 TOTAL ASSETS                                  20,824                 19,890 
 
 LIABILITIES 
 CURRENT LIABILITIES 
 Trade and other payables             1,797                 1,364 
  Deferred income                     7,107                 6,811 
 Current tax payable                    541                   231 
 Financial liabilities                  385                 1,903 
 
 TOTAL CURRENT LIABILITIES                     9,830                  10,309 
 
 NON-CURRENT LIABILITIES 
 Financial liabilities                  448                   281 
 Retirement benefit obligations       3,933                 3,881 
 
 TOTAL NON-CURRENT LIABILITIES                 4,381                   4,162 
 

(MORE TO FOLLOW) Dow Jones Newswires

April 05, 2016 02:00 ET (06:00 GMT)

 TOTAL LIABILITIES                             14,211                 14,471 
 
 EQUITY 
 Share capital                        1,304                 1,221 
 Share premium                        7,903                 7,892 
 Merger reserve                       1,241                 (326) 
 Shares to be issued                    641                   378 
 Translation reserve                    204                   228 
 Retained earnings                  (4,680)               (3,974) 
 
 
   TOTAL EQUITY ATTRIBUTABLE TO 
   OWNERS OF THE PARENT                         6,613                  5,419 
 
 TOTAL EQUITY AND LIABILITIES                  20,824                 19,890 
 
 

Consolidated Statement of Cashflows

For the year ended 31 December 2015

 
                                                       Unaudited               Audited 
                                                      Year ended            Year ended 
                                                31 December 2015      31 December 2014 
                                               GBP000     GBP000      GBP000    GBP000 
 CASH FLOWS FROM OPERATING ACTIVITIES 
 (Loss)/Profit before taxation                  (361)                    212 
 Adjustments for: 
 Depreciation                                     156                    127 
 Amortisation of intangibles                    1,016                    937 
 Share based payments                             263                    108 
 Retirement benefit obligations                 (427)                  (398) 
 Finance income                                   (4)                    (9) 
 Finance costs                                    272                    359 
 Increase in deferred contingent                1,361                      - 
  consideration 
 
                                                           2,276                 1,336 
 CASH FLOWS FROM OPERATIONS BEFORE 
  MOVEMENTS IN WORKING CAPITAL 
 Movements in working capital: 
 Increase in inventories                        (313)                  (196) 
 Increase in trade and other receivables         (71)                (1,436) 
 Increase in trade and other payables 
  and deferred income                             493        109         743     (889) 
 
 CASH GENERATED FROM OPERATIONS                            2,385                   447 
 Finance costs                                   (86)                   (65) 
 Income taxes                                     205        119         100        35 
 
 NET CASH GENERATED FROM OPERATING 
  ACTIVITIES                                               2,504                   482 
 
 CASH FLOWS FROM INVESTING ACTIVITIES 
 Finance income received                            4                      9 
 Purchase of intangible assets                  (612)                  (369) 
 Purchase of property, plant and 
  equipment                                     (113)                  (124) 
 Payment of deferred contingent 
  consideration                                 (950)                  (302) 
 Repayment of capital from finance                (8)                      - 
  leases 
 
 NET CASH USED IN INVESTING ACTIVITIES                   (1,679)                 (786) 
 
 CASH FLOWS FROM FINANCING ACTIVITIES 
 Proceeds from issue of share                      12                      - 
  capital 
 Loan note repaid                               (303)                      - 
 Finance lease interest                           (4)                      - 
 
 NET CASH USED IN FINANCING ACTIVITIES                     (295)                     - 
 
 NET INCREASE/(DECREASE) IN CASH AND 
  CASH EQUIVALENTS                                           530                 (304) 
 Cash and cash equivalents at 
  start of year                                            1,676                 2,053 
 Effects of exchange rate changes 
  on the balance of cash held in 
  foreign currencies                                        (23)                  (73) 
 
 CASH AND CASH EQUIVALENTS AT 
  END OF YEAR                                              2,183                 1,676 
 
 

Consolidated Statement of Changes in Equity

 
                                Called            Share     Merger    Shares   Translation    Retained     Total 
                              up share          premium    reserve     to be       reserve    earnings    equity 
                               capital                                issued 
                                GBP000           GBP000     GBP000    GBP000        GBP000      GBP000    GBP000 
 
 Balance as 
  at 
  1 January 2014                 1,176            7,892      (932)       270           194     (3,627)     4,973 
 Profit for 
  the year                           -                -          -         -             -         150       150 
 Other comprehensive 
  expense for 
  the year                           -                -          -         -            34       (497)     (463) 
 
 Total comprehensive 
  income/(expense)                   -                -          -         -            34       (347)     (313) 
 Shares issued                      45                -        606         -             -           -       651 
 Share based 
  payment                            -                -          -       108             -           -       108 
 
 Balance at 
  31 December 
  2014                           1,221            7,892      (326)       378           228     (3,974)     5,419 
 Loss for the 
  year                               -                -          -         -             -       (428)     (428) 
 Other comprehensive 
  expense for 
  the year                           -                -          -         -          (24)       (278)     (302) 
 
 Total comprehensive 
  expense                            -                -          -         -          (24)       (706)     (730) 
 Shares issued                      83               11      1,567         -             -           -     1,661 
 Share based 
  payment                            -                -          -       263             -           -       263 
 
 Balance as 
  at 31 December 
  2015                           1,304            7,903      1,241       641           204     (4,680)     6,613 
 
 
 

Notes to the Financial Statements

1. Basis of Preparation

FINANCIAL INFORMATION

The preliminary financial information does not constitute statutory accounts within the meaning of section 434 of the Companies Act 2006 but is derived from accounts for the years ended 31 December 2015 and 31 December 2014. The figures for the year ended 31 December 2014 were audited. The preliminary financial information is prepared on the same basis as will be set out in the statutory accounts for the year ended 31 December 2015. The figures for the year ended 31 December 2015 are unaudited.

The presentation of the Consolidated Statement of Comprehensive Income has changed from the previous audited financial statements. The change includes the depreciation charge being presented on the face of the Consolidated Statement of Comprehensive Income rather than being included in operating expenses. The change has been made to provide clarity in the calculation of earnings before interest, taxation, depreciation and non-recurring costs (EBITDA).

The presentation of the Consolidated Statement of Financial Position has changed from the previous audited financial statements. The change is to show deferred income on the face of the Consolidated Statement of Financial Position rather than being included in trade and other payables.

It is the opinion of the directors that the above changes are considered more appropriate to the readers and users to better understand the performance and position of the Group.

The preliminary financial information was approved for issue by the Board of Directors on 4 April 2016.

The statutory accounts for the year ended 31 December 2015 will be delivered to the Registrar of Companies following the Company's Annual General Meeting. Statutory accounts for the year ended 31 December 2014 have been filed with the Registrar of Companies. The auditor's report on those 2014 accounts was unqualified and did not contain any statement under Section 498 (2) or (3) of the Companies Act 2006.

GENERAL INFORMATION

The principal activity of the Group is the provision of world class information solutions for Life Sciences research and development in the early phase drug development market. Instem plc is a company incorporated in England and Wales under the Companies Act 2006 and domiciled in the UK. The registered office is Diamond Way, Stone Business Park, Stone, Staffordshire, ST15 0SD, UK.

BASIS OF ACCOUNTING

While the financial information included in this preliminary announcement has been prepared in accordance with the recognition and measurement criteria of International Financial Reporting Standards (IFRS), as adopted by the European Union (EU), this announcement does not in itself contain sufficient information to comply with IFRSs.

The Group's accounting reference date is 31 December.

GOING CONCERN

Having made appropriate enquiries, the directors consider that the Group has adequate resources to enable it to continue in operation for the foreseeable future. The Group has a significant proportion of recurring revenue from a well-established global customer base, supported by a largely fixed cost base.

The financial position of the Group, its cash flows and liquidity position are set out in the primary statements of this financial information. Detailed projections have been made for the 12 months following the approval of the financial statements and sensitivity analysis undertaken. This work gives the directors confidence as to the future trading performance.

Accordingly, the directors continue to adopt the going concern basis for the preparation of the financial statements.

2. Segmental Reporting

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For management purposes, the Group is currently organised into one operating segment - Global Life Sciences.

Segment results, assets and liabilities include items directly attributable to a segment as well as those that can be allocated on a reasonable basis.

 
 
                                              2015      2014 
                                            GBP000    GBP000 
  INFORMATION BY PRODUCT TYPE 
  Licence fees                               4,612     2,734 
  Annual support fees                        7,383     6,984 
  SaaS subscription fees                     2,076     1,822 
  Professional services                      2,042     1,763 
  Funded development initiatives               208       126 
                                          --------  -------- 
                                            16,321    13,429 
                                          ========  ======== 
 
 
 
 
                                               2015      2014 
                                             GBP000    GBP000 
 INFORMATION BY GEOGRAPHICAL LOCATION 
 UK                                           2,004     2,141 
 Rest of Europe                               3,592     2,699 
 USA and Canada                               9,429     7,583 
 Rest of World                                1,296     1,006 
                                           --------  -------- 
                                             16,321    13,429 
                                           ========  ======== 
 
 
 
                                              NON-CURRENT ASSETS EXCLUDING DEFERRED TAXATION 
                                                               2015                     2014 
                                                             GBP000                   GBP000 
 INFORMATION BY GEOGRAPHICAL LOCATION 
 UK                                                          12,331                   12,664 
 USA and Canada                                                  39                       16 
 Rest of World                                                   41                       22 
                                           ------------------------  ----------------------- 
                                                             12,411                   12,702 
                                           ========================  ======================= 
 
 

MAJOR CUSTOMERS

No single customer generated more than 10% of the Group revenue (2014: Nil).

3. Income Taxes

 
                                                     2015      2014 
  Income taxes recognised in profit                GBP000    GBP000 
  or loss 
  Current tax: 
  UK corporation tax on result for                     98           - 
   the year 
  Foreign tax                                         411         272 
  Foreign tax in respect of previous 
   years                                            (302)         239 
  Adjustments in respect of previous 
   years                                               61       (171) 
  Adjustments in respect of R&D tax 
   credit                                           (173)        (92) 
                                                 --------  ---------- 
  Total current tax                                    95         248 
                                                 --------  ---------- 
  Deferred tax: 
  Current year credit                               (315)        (30) 
  Adjustment in respect of previous 
   years                                              157       (103) 
  Retirement benefit obligation                       130        (53) 
                                                 --------  ---------- 
  Total deferred tax                                 (28)       (186) 
                                                 --------  ---------- 
 
    Total income tax expense recognised 
    in the current year                                67          62 
                                                 ========  ========== 
 
 
 
                                                 2015      2014 
                                               GBP000    GBP000 
 The income tax expense can be reconciled 
  to the accounting result as follows: 
 
 (Loss)/Profit before tax                       (361)         212 
 (Loss)/Profit before tax multiplied 
  by standard rate of corporation 
  tax in the UK 20.25% (2014: 21.50%)            (73)          46 
 
 Effects of: 
 Expenses not deductible for tax 
  purposes                                        367          33 
 Fixed asset timing differences                    17         (9) 
 Differences in overseas tax rates                165         109 
 Adjustments in respect of prior 
  years                                          (84)        (35) 
 Adjustment in respect of R&D tax               (173)           - 
  credit 
 Other timing differences                       (152)           - 
  Tax losses utilised                               -        (82) 
 
 Total income tax expense recognised 
  in profit or loss                                67          62 
                                             ========  ========== 
 
 

4. Non-recurring costs

The 2015 non-recurring charge of GBP1.4m arose following the early agreement of the final deferred contingent consideration relating to the 2013 acquisition of Instem Clinical (formerly Logos Technologies) after all profit targets were exceeded.

The 2014 non-recurring charge included a net charge of GBP0.06m relating to a trade dispute, net of insurance proceeds of GBP0.09m, and GBP0.07m of professional fees associated with the Perceptive Instruments acquisition in 2013.

5. Earnings per share

Basic and fully diluted

Basic earnings per share are calculated by dividing the profit/(loss) attributable to ordinary shareholders by the weighted average number of ordinary shares in issue during the year. Diluted earnings per share is calculated by adjusting the weighted number of ordinary shares outstanding to assume conversion of all dilutive potential shares arising from the share option scheme. The dilutive impact of the share options is calculated by determining the number of shares that could have been acquired at fair value (determined as the average market share price of the Company's shares) based on the monetary value of the subscription rights attached to the outstanding share options.

 
                                         2015                                               2014 
                     Profit after         Weighted     Earnings per     Profit after         Weighted     Earnings per 
                              tax   average number            share              tax   average number            share 
                                         of shares                                          of shares 
 
                                              '000                                               '000 
                           GBP000                             Pence           GBP000                             Pence 
 
 Earnings per 
  share - Basic             (428)           12,398            (3.5)              150           12,063              1.2 
 Potentially                    -               -*                -                -              155                - 
 dilutive shares 
                  ---------------  ---------------  ---------------  ---------------  ---------------  --------------- 
 Earnings per 
  share - 
  Diluted                   (428)           12,398            (3.5)              150           12,218              1.2 
                  ===============  ===============  ===============  ===============  ===============  =============== 
 

*Dilutive share options have been excluded from the calculation as in accordance with IAS 33, 'Earnings per share', as they are only included where the impact is dilutive.

Adjusted

Adjusted earnings per share is calculated after adjusting for the effect of foreign currency exchange on the revaluation of inter-company balances included in finance income/(costs), non-recurring items and amortisation of intangibles on acquisitions. Diluted adjusted earnings per share is calculated by adjusting the weighted number of ordinary shares outstanding to assume conversion of all dilutive potential shares arising from the share option scheme. The dilutive impact of the share options is calculated by determining the number of shares that could have been acquired at fair value (determined as the average market share price of the Company's shares) based on the monetary value of the subscription rights attached to the outstanding share options.

 
                                         2015                                               2014 
                         Adjusted         Weighted         Adjusted         Adjusted         Weighted         Adjusted 
                     Profit after   average number     Earnings per     Profit after   average number     Earnings per 
                              tax        of shares            share              tax        of shares            share 
 
                                              '000                                               '000 
                           GBP000                             Pence           GBP000                             Pence 
 
 Earnings per 
  share - Basic             1,644           12,398             13.3            1,009           12,063              8.4 
 Potentially 
  dilutive 
  shares                        -              337                -                -              155                - 
                  ---------------  ---------------  ---------------  ---------------  ---------------  --------------- 
 Earnings per 
  share - 
  Diluted                   1,644           12,735             12.9            1,009           12,218              8.3 
                  ===============  ===============  ===============  ===============  ===============  =============== 
 
 

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 Reconciliation of reported (loss)/profit after        2015       2014 
  tax to adjusted profit after tax:                 GBP'000    GBP'000 
 Reported (loss)/profit after tax                     (428)        150 
 Non-recurring costs                                  1,426        123 
 Amortisation of acquired intangibles                   640        640 
 Foreign exchange differences on revaluation of 
  inter-co balances                                       6         96 
 
 
   Adjusted profit after tax                          1,644      1,009 
                                                  =========  ========= 
 

6. Post balance sheet event

Following the end of the financial year, in February 2016 the Company announced it had raised GBP5.0 million (before expenses) by way of a placing of 2,500,000 New Ordinary Shares with new and existing investors. The Board intends to use the proceeds of this placing, along with existing cash resources, to continue the Group's acquisition strategy and to provide additional working capital.

7. Annual report and accounts

Copies of the Annual Report and Accounts will be posted to the Company's shareholders and will be available, along with this announcement, on Instem's website at http://investors.instem.com.

This information is provided by RNS

The company news service from the London Stock Exchange

END

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