By Anora Mahmudova, MarketWatch

NEW YORK (MarketWatch) -- Selling of U.S. stocks accelerated early Tuesday afternoon as investors dumped momentum plays and economically sensitive stocks such as American International Group Inc. and Amazon.com Inc.

Even deal news, generally a positive for the market, failed to lift prices. The calendar also didn't provide its usual support; Tuesdays on the whole have been the strongest part of the week this year.

The S&P 500 (SPX) was down 13 points, or 0.7%, at 1,871.38, with the financial and consumer-discretionary sectors leading the decline. The Dow Jones Industrial Average (DJI) dropped 112 points, or 0.7%, to 16,417.75. The Nasdaq Composite (RIXF) lost 43 points, or 1%, to 4,095.40.

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Analysts were hard-pressed to pinpoint a single reason for the market's decline.

The sole U.S. economic report covered the trade deficit, which narrowed in March to $40.4 billion, slightly above the consensus of $40 billion.

"Today's trading is very atypical. There is very little volume, and deal news, which usually a positive for markets, is being ignored," said Kim Caughey Forrest, senior equity analyst at Fort Pitt Capital.

Twitter tumbles, Office Depot surges on earnings

In deal news, Merck (MRK) agreed to sell its consumer-products business, including the allergy-treatment Claritin and nasal decongestant Afrin, to German drug maker Bayer AG for $14.2 billion. Shares fell 2.5%. Also read: Why the deal isn't helping Merck shares.

Office Depot Inc. shares (ODP) surged 17% to $4.88, after the electronics retailer raised its outlook for 2014 operating profit and said it plans to close at least 400 U.S. stores by the end of 2016.

Shares of Athenahealth (ATHN) fell 14%, after David Einhorn of Greenlight Capital said at a conference Monday that the health-information technology firm is "overpriced" and "caught up in a bubble."

American International Group (AIG) shares dropped 4.1% after the insurer reported a substantial fall in first-quarter profit late Monday.

Discovery Communications, Inc. (DISCA) shares dropped 3.4% after disappointing first-quarter results. The owner of Discovery Channel and Animal Planet said profit edge down 0.4% as higher expenses cut into revenues.

Twitter Inc. (TWTR) shares tumbled 15% as hundreds of millions of shares held by insiders became available for sale in the open market. The stock took a hit even after Twitter management sought to reassure investors by announcing that major investors were not planning to unload huge chunks of their shares.

DirecTV (DTV) shares rose 2.7% even as the company's first-quarter earnings fell 19%. The company, however, continued to boost its subscriber numbers, surpassing 38 million customers.

Quarterly results from media and entertainment conglomerate Walt Disney Co. (DIS), upscale grocer Whole Foods Market Inc. (WFM) as well as e-commerce and daily-deals company Groupon Inc. (GRPN) are due after Wall Street's regular close.

Disney is projected to report second-quarter earnings of 96 cents a share, according to a consensus survey by FactSet, while Whole Foods is projected to report earnings of 41 cents a share in the second quarter. Groupon is forecast to post a loss of 3 cents a share in the first quarter.

European stocks end lower

European stocks reversed earlier gains and closed mostly lower.

On Tuesday, the Organization for Economic Cooperation and Development said the European Central Bank should immediately cut its benchmark interest rate, to end a period of too-low inflation in the euro zone.

Asian stocks were slightly higher, with Australia up after the country's central bank held interest rates steady. Markets in Japan, South Korea and Hong Kong were closed.

In the commodities markets Tuesday, gold (GCM4) futures fell slightly. Crude for June delivery (CLM4) gained slightly but still remained below the $100 a barrel level. Meanwhile, the pound (GBPUSD) bought $1.6980 and traded at levels not seen since at least 2009 after strong U.K. services data.

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