Amgen Inc.'s (AMGN) second-quarter earnings edged lower as increased expenses for acquisition- and reorganization-related charges and other items masked the biopharmaceutical giant's revenue growth.

For the year, the company raised its per-share earnings projection to $7.30 to $7.45, from its previous view for above the midpoint of $7.05 to $7.35, and now expects revenue at the upper end of its previous projected range of $17.8 billion to $18.2 billion.

Amgen, the world's largest independent biotechnology company, is in a transitional period as it looks to expand further into international markets, gain approvals for new experimental drugs, and increase sales of its arthritis and osteoporosis drugs. Many of the company's core products face the potential of new competition as they lose patent protection in the coming years.

Chairman and Chief Executive Robert A. Bradway said, "We saw solid product trends during the second quarter and are carrying good momentum into the second half."

Amgen reported a profit of $1.26 billion, down from $1.27 billion a year earlier. On a per-share basis, earnings were up at $1.65 from $1.61 on fewer shares outstanding. Excluding acquisition- and restructuring-related impacts and other items, adjusted earnings were up at $1.89 from $1.83. Revenue increased 4.5% to $4.68 billion.

Analysts polled by Thomson Reuters recently expected $1.74 and $4.49 billion.

Research-and-development expenses increased 17%, mostly in support of its later-stage clinical programs.

Neulasta sales rose 10% amid price increases, higher wholesaler inventory and a Medicaid rebate adjustment.

Sales of arthritis drug Enbrel were up 9%, mostly owing to higher prices.

The company's osteoporosis drugs, Xgeva and Prolia, reported sales growth of 39% and 57%, respectively.

Shares were up 1.1% at $112.46 in recent after-hours trading as adjusted earnings and revenue beat expectations. Through the close, the stock is up 29% this year.

Write to Tess Stynes at tess.stynes@wsj.com

Subscribe to WSJ: http://online.wsj.com?mod=djnwires

Onyx Pharmaceuticals, Inc. (MM) (NASDAQ:ONXX)
Historical Stock Chart
From Jun 2024 to Jul 2024 Click Here for more Onyx Pharmaceuticals, Inc. (MM) Charts.
Onyx Pharmaceuticals, Inc. (MM) (NASDAQ:ONXX)
Historical Stock Chart
From Jul 2023 to Jul 2024 Click Here for more Onyx Pharmaceuticals, Inc. (MM) Charts.