MUSC and Lumera to Develop Antibody Array for Protein Expression Profiling
April 30 2007 - 8:50AM
Business Wire
Lumera Corporation (NASDAQ:LMRA), a leader in the emerging field of
nanotechnology, announced today that it has extended its
collaboration agreement with the Medical University of South
Carolina (MUSC). In partnership with Lumera scientists, MUSC
researchers intend to develop an antibody array that will measure
the levels and modifications of patient mitochondrial proteins.
Under the agreement, Lumera will retain rights to commercialize all
jointly developed intellectual property. �Changes in mitochondrial
proteins are known to be markers for certain pathologies and many
adverse drug effects. The high throughput and label-free nature of
Lumera�s platform enables us to develop an assay that will have
significant time and cost advantages over existing technologies. In
addition, we are very excited by the prospects of identifying new
biomarkers,� said Dr. Craig Beeson, Associate Professor of
Pharmaceutical Sciences at MUSC and the Principle Investigator on
this project. �We are obviously thrilled to be extending this
agreement,� said Dr. Timothy Londergan, Bioscience Business Unit
Director at Lumera. �Professor Beeson�s vision for this project
highlights the world class nature of the science being pursued at
MUSC. And while academically interesting, this project has
implications across pharma that are significant.� Biomarkers are
important to pharmaceutical manufacturers because they are often
clear indicators of a diseased state and adverse drug effects. For
example, an elevated serum level of prostate-specific antigen is a
biomarker for prostate cancer. By identifying specific disease or
toxicant biomarkers, pharmaceutical companies can monitor outcome
of drugs targeted to these diseases to improve patient outcome and
avoid the adverse effects. Unexpected adverse effects are the
biggest hurdle in drug development. The biomarker market
opportunity is expected to grow dramatically over the next several
years. Business Insights, a market research firm, forecasts that
the $5.4 billion biomarker market that existed in 2005 will
quadruple to an estimated $21.1 billion in 2012 fueled by growth in
proteomics and metabolomics biomarker discovery. �Professor
Beeson�s applications, along with projects in development at our
two other academic beta sites, are in the category of biomarker
discovery. In particular, these early adopters of our technology
are interested in measuring the up- and down-regulation of
thousands of proteins as a result of disease, stress or drug
therapy. Lumera�s ProteomicProcessor� instrument system and
NanoCapture� microarray slides enable the measurement of thousands
of proteins simultaneously, thereby dramatically increasing the
efficiency of the biomarker discover process,� said Ron Dudek,
Lumera�s Director of Business Development. About MUSC The Medical
University of South Carolina's mission is to preserve and optimize
human life in South Carolina and beyond. MUSC is the core of the
state�s largest medical complex, its only tertiary/quaternary care
referral center, and its only free-standing academic health center.
The university offers a full range of programs in the biomedical
and health sciences serving as a setting for clinical research,
contributing financial, facility and intellectual resources to
conduct research, and providing opportunity for appropriate
participation of hospital patients in research and treatment
protocols. MUSC is listed by the National Science Foundation as one
of the top 100 universities and colleges in the nation for
garnering federal dollars for science and engineering. About Lumera
Lumera is an emerging leader in the field of nanotechnology. The
company designs proprietary molecular structures and polymer
compounds for a broad range of bioscience, electro-optic, and
specialty nanotechnology applications. The company also has
developed proprietary processes for fabricating such devices. For
more information, please visit http://www.lumera.com/. Certain
statements contained in this release are forward-looking statements
that involve a number of risks and uncertainties. Factors that
could cause actual results to differ materially from those
projected in the company's forward-looking statements include the
following: market acceptance of our technologies and products; our
ability to obtain financing; our financial and technical resources
relative to those of our competitors; our ability to keep up with
rapid technological change; government regulation of our
technologies; our ability to enforce our intellectual property
rights and protect our proprietary technologies; the ability to
obtain additional contract awards and to develop partnership
opportunities; the timing of commercial product launches; the
ability to achieve key technical milestones in key products; and
other risk factors identified from time to time in the company's
SEC reports, including in its Annual Report on 10-K for the year
ended December 31, 2003, and its Quarterly Reports on Form 10-Q.
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