Inhibitex Announces Data Presentation at the 60th Annual Meeting of the American Association for the Study of Liver Diseases ...
October 26 2009 - 11:29AM
Business Wire
Inhibitex, Inc. (NASDAQ: INHX) announced today that a poster
presentation describing preclinical data on INX-189, the lead
compound from its HCV nucleotide polymerase inhibitor program, will
be presented by Dr. Joseph M. Patti, Chief Scientific Officer and
Senior Vice President of R&D, at the 60th Annual Meeting of the
American Association for the Study of Liver Diseases (AASLD) in
Boston, MA. The full abstract can be viewed at the AASLD website at
www.aasld.org.
The poster (#1611 Patti, et al), entitled “Pharmacological
Properties and In Vitro Characterization of INX-189, a Liver
Targeted Phosphoramidate Nucleoside Analogue Inhibitor of NS5b”
will be presented in the HCV Therapy: Preclinical and Early
Clinical Development session from 8:00 am – 1:00 pm on Tuesday,
November 3rd, 2009.
About HCV and Protides
Hepatitis C is a disease of the liver caused by the hepatitis C
virus (HCV). It is estimated that approximately 4 million Americans
and 170 million individuals worldwide are infected with HCV. HCV
can cause chronic liver disease, cirrhosis and cancer, and is the
leading cause of liver transplant in the United States. Inhibitex
is developing a series of proprietary phosphoramidates, or protide
nucleoside inhibitors, that target the RNA-dependent RNA polymerase
(NS5b) of HCV. Protides are designed to by-pass the rate limiting
first step in the formation of the active nucleoside triphosphate.
INX-189 is a protide of a 2’-C-methyl guanosine analogue. The
Company believes that its protides possess several pharmacological
advantages over nucleosides alone and potentially other nucleotide
prodrugs. These advantages include greater potency, a rapid
conversion of the protide into its active form in the liver, and
potentially less toxicity due to reduced systemic exposure of the
nucleoside.
About Inhibitex
Inhibitex, Inc., headquartered in Alpharetta, Georgia, is a
biopharmaceutical company focused on developing products to treat
serious infectious diseases. In addition to INX-189, the Company’s
pipeline includes FV-100, its clinical-stage nucleoside analogue in
Phase II development for the treatment of herpes zoster (shingles).
The Company has also licensed the use of its proprietary MSCRAMM®
protein technology to Wyeth for the development of staphylococcal
vaccines.
For additional information about the Company, please visit
www.inhibitex.com.
Safe Harbor Statement
This press release contains forward-looking statements within
the meaning of the Private Securities Litigation Reform Act of 1995
that involve substantial risks and uncertainties. All statements,
other than historical facts included in this press release,
including statements regarding the Company’s belief that its
protides possess several pharmacological advantages over
nucleosides alone and potentially other nucleoside prodrugs, are
forward looking statements. These results and expectations may not
be achieved in the future and various important factors could cause
actual results or events to differ materially from the
forward-looking statements that the Company makes, including the
risk of: the Company not obtaining regulatory approval on a timely
basis, or at all, to advance the development of INX-189 into
clinical trials; the results of ongoing or future preclinical
studies of INX-189 not supporting its further development;
obtaining, maintaining and protecting the intellectual property
incorporated into and supporting the commercial viability of the
Company’s product candidates; and other cautionary statements
contained elsewhere herein and in its Annual Report on Form 10-K
for the year ended December 31, 2008, as filed with the Securities
and Exchange Commission, or SEC, on March 23, 2009 and its
Quarterly Report on Form 10-Q for the quarter ended June 30, 2009
as filed with the SEC on August 12, 2009. Given these
uncertainties, you should not place undue reliance on these
forward-looking statements, which apply only as of the date of this
press release.
There may be events in the future that the Company is unable to
predict accurately, or over which it has no control. The Company's
business, financial condition, results of operations and prospects
may change. The Company may not update these forward-looking
statements, even though its situation may change in the future,
unless it has obligations under the Federal securities laws to
update and disclose material developments related to previously
disclosed information. The Company qualifies all of the information
contained in this press release, and particularly its
forward-looking statements, by these cautionary statements.
Inhibitex® and MSCRAMM® are registered trademarks of Inhibitex,
Inc.
Inhibitex, Inc. (MM) (NASDAQ:INHX)
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