Catalyst Rx, the pharmacy benefit management (PBM) subsidiary of Catalyst Health Solutions, Inc. (NASDAQ: CHSI), announced the award of a new service contract with Wellmark following a competitive bid process. Wellmark does business as Wellmark Blue Cross and Blue Shield of Iowa and its subsidiaries include Wellmark Blue Cross and Blue Shield of South Dakota and Wellmark Health Plan of Iowa, Inc. Wellmark Blue Cross and Blue Shield is an independent licensee of the Blue Cross and Blue Shield Association. The new contract, effective January 1, 2011, will cover approximately 1.2 million members.

Catalyst Rx began administering pharmacy benefits for Wellmark on July 1, 2006. "Wellmark's selection of Catalyst Rx reflects continued success in our efforts to provide clients with heightened performance accountability, transparency and innovative solutions to managing prescription benefits," said David Blair, Chief Executive Officer of Catalyst Health Solutions. "We appreciate the opportunity to continue building on our collaborative partnership to drive the most care- and cost-effective solutions.”

"Catalyst’s transparent pricing model and ability to deliver customized programs have allowed us to deliver a high-quality pharmacy benefit to members while effectively reducing our pharmacy costs,” says Wellmark Pharmacy Director Matt Hosford, RPH. “Leveraging our combined expertise, and our commitment to quality and service excellence, we will provide greater value for our customers.”

About Catalyst Health Solutions, Inc. (www.chsi.com)

Catalyst Health Solutions, Inc. is built on strong, innovative principles in the management of prescription drug benefits and provides an unbiased, client-centered philosophy resulting in industry-leading client retention rates. The Company's subsidiaries include Catalyst Rx, a full-service pharmacy benefit manager serving more than 7 million lives in the United States and Puerto Rico; HospiScript Services, LLC, one of the largest providers of pharmacy benefit management services to the hospice industry; and Immediate Pharmaceutical Services, Inc., a fully-integrated prescription mail service facility in Avon Lake, Ohio. The Company's clients include self-insured employers, including state and local governments, managed care organizations, unions, hospices, third-party administrators and individuals.

About Wellmark Blue Cross and Blue Shield (www.wellmark.com)

Wellmark Blue Cross and Blue Shield is a mutual insurance company owned by its policyholders. Wellmark and its subsidiaries provide health coverage to more than 2 million members in Iowa and South Dakota. And through the Blue Cross Blue Shield Association, Wellmark is part of a trusted national network that covers more than 100 million people.

The Company has an innovative approach to improving the health of its members and their communities. Wellmark offers flexible benefit designs, competitive prices and is committed to working with physicians, hospitals, customers, and other stakeholders to transform the health care system in Iowa and South Dakota to slow rising health care costs.

This press release may contain “forward-looking statements” as defined in the Private Securities Litigation Reform Act of 1995. These statements involve a number of risks and uncertainties that might materially affect our results, particularly those risks referred to in our Annual Report on Form 10-K for the year ended December 31, 2009, and in our Quarterly Report on Form 10-Q for the quarter ended June 30, 2010 under “Item 1A. Risk Factors.” Readers are urged to carefully review and consider the various disclosures made in our Annual Report on Form 10-K, our Forms 10-Q, and our other filings with the Securities and Exchange Commission that attempt to advise interested parties of the risks and uncertainties that may affect our business. Catalyst Health Solutions, Inc. does not undertake any obligation to update forward-looking statements, whether as a result of new information, future events, or other developments.

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