Applied Imaging Complies With Nasdaq Rule Regarding 2004 Form 10-K SAN JOSE, Calif., May 4 /PRNewswire-FirstCall/ -- Applied Imaging Corp. (NASDAQ:AICXE) today announced that its financial statements for the year ended December 31, 2004, filed with its Annual Report on Form 10-K on April 27, 2005, included an audit report containing a going concern qualification. Its announcement is made in compliance with Nasdaq's Marketplace Rule 4350(b) requiring Nasdaq-listed companies to make a separate announcement by press release when they receive an audit opinion containing a going concern qualification. About Applied Imaging Applied Imaging Corp., based in San Jose, California, is the leading supplier of automated imaging and image analysis systems for the detection and characterization of chromosomes and molecular markers in genetics and pathology laboratories. The Company develops, manufactures and markets a range of scanning and image analysis systems for both conventional (brightfield) and fluorescent microscopic analysis of cellular and tissue specimens. Products are sold to hospital laboratories, cancer centers, prenatal clinics and research institutions for both research and clinical purposes. The Company has installed over 3,500 of its systems in over 1000 laboratories in more than 60 countries around the world. Beyond its core business, through its wholly-owned subsidiary, CTC, Inc., the Company is also developing a system for the detection, quantification and characterization of tumor cells in the blood of cancer patients. More information about Applied Imaging can be found at http://www.aicorp.com/. Contacts: For More Information: CCG Investor Relations Crocker Coulson, President 15300 Ventura Boulevard, Suite 303 Sherman Oaks, CA 91403 (818) 789-0100 Applied Imaging Corp. Terry Griffin, Chief Financial Officer 120 Baytech Drive, San Jose, CA 95134 (408) 719-6417 DATASOURCE: Applied Imaging Corp. CONTACT: Crocker Coulson, President of CCG Investor Relations, +1-818-789-0100, , for Applied Imaging Corp.; or Terry Griffin, Chief Financial Officer of Applied Imaging Corp., +1-408-719-6417, Web site: http://www.aicorp.com/

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