GERMANTOWN, Md., March 23 /PRNewswire-FirstCall/ -- Avalon Pharmaceuticals, Inc. (Nasdaq and ArcaEx(R): AVRX), a biopharmaceutical company focused on the discovery and development of small molecule therapeutics, today announced that Kenneth C. Carter, Ph.D., President and CEO of Avalon Pharmaceuticals, will preside over The NASDAQ Stock Market Closing Bell at 4:00 p.m. Eastern Time on Monday March 27, 2006. "Our debut as a NASDAQ-listed company this past September marked a milestone of which we are very proud and we are pleased to celebrate it at the Closing Bell ceremony at NASDAQ," stated Kenneth C. Carter, Ph.D., President and CEO of Avalon. Web Cam: To view the live Closing Bell, visit http://www.nasdaq.com/reference/marketsite_about.stm and follow the instructions below: - Scroll to the bottom of the page under the heading MarketSite Live Web cam and click on Windows Media Player. - Viewers should download the web cam at 3:45 p.m. Eastern Time in order to have time to trouble-shoot in case of technical difficulties. Broadcast Feed: The closing bell is available from 3:50 to 4:05 p.m. on uplink IA-6 C-band / transponder 17. The downlink frequency is 4040 Vertical; audio: 6.2-6.8. The feed can also be found on Waterfront fiber 1623. About Avalon Pharmaceuticals, Inc. Avalon Pharmaceuticals is a biopharmaceutical company focused on the discovery and development of small molecule therapeutics for the treatment of cancer. Avalon seeks to discover and develop novel therapeutics through the use of a comprehensive, innovative and proprietary suite of technologies based upon large-scale gene expression analysis which it calls AvalonRx(R). This platform facilitates drug discovery by expanding the range of therapeutic targets for drug intervention, including targets and target pathways frequently considered intractable using conventional HTS approaches, allows more informed decisions about which compounds to advance towards clinical trials, and facilitates drug development through identification of biomarkers of efficacy that can stratify patients or provide early indicators of response. Avalon Pharmaceuticals was established in 1999 and is headquartered in Germantown, Maryland. Contacts: Avalon Pharmaceuticals, Inc. Noonan Russo Gary Lessing Wendy Lau (Media) Executive Vice President and CFO Tel: (212) 845-4272 Tel: (301) 556-9900 Fax: (301) 556-9910 Jane Petrino (Investors) Email: Tel: (212) 845-4274 DATASOURCE: Avalon Pharmaceuticals, Inc. CONTACT: Gary Lessing, Executive Vice President and CFO of Avalon Pharmaceuticals, Inc., +1-301-556-9900, Fax +1-301-556-9910, ; or Wendy Lau - Media, +1-212-845-4272, or Jane Petrino, Investors, +1-212-845-4274, both of Noonan Russo for Avalon Pharmaceuticals, Inc. Web site: http://www.nasdaq.com/reference/marketsite_about.stm

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