All Primary and Secondary Endpoints Met NOVATO, Calif. and GENEVA, March 15 /PRNewswire-FirstCall/ -- BioMarin Pharmaceutical Inc. (Nasdaq and SWX: BMRN) and Serono (virt-x: SEO and NYSE: SRA) announced today positive results of a Phase 3, double-blind, placebo-controlled clinical study of Phenoptin(TM) (sapropterin dihydrochloride), an investigational oral small molecule for the treatment of phenylketonuria (PKU). Results confirm that all pre-specified primary and secondary endpoints were met and data from the Phase 3 study demonstrate a statistically significant reduction at six weeks in blood phenylalanine (Phe) levels (p