FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

WEXFORD CAPITAL LP

2. Date of Event Requiring Statement (MM/DD/YYYY)
1/25/2013 

3. Issuer Name and Ticker or Trading Symbol

Arno Therapeutics, Inc [ARNI]

(Last)        (First)        (Middle)

411 WEST PUTNAM AVENUE, SUITE 125

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            ___ X ___ 10% Owner
_____ Officer (give title below)          _____ Other (specify below)

(Street)

GREENWICH, CT 06830       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock   418876   I   By: Kappa Investors LLC   (1) (3) (4)
Common Stock   2828169   I   By: Wexford Spectrum Investors LLC   (2) (3) (4)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Warrants (right to buy)   6/2/2008   6/2/2013   Common Stock   24732   $2.42   I   By: Kappa Investors LLC   (1) (3) (4)
Class A Warrants (right to buy)   9/9/2010   3/9/2013   Common Stock   13441   $0.5268   I   By: Kappa Investors LLC   (1) (3) (4)
Class B Warrants (right to buy)   9/9/2010   9/9/2015   Common Stock   70564   $0.5649   I   By: Kappa Investors LLC   (1) (3) (4)
Class A Warrants (right to buy)   9/9/2010   3/9/2013   Common Stock   85759   $0.5268   I   By: Wexford Spectrum Investors LLC   (2) (3) (4)
Class B Warrants (right to buy)   9/9/2010   9/9/2015   Common Stock   450236   $0.5649   I   By: Wexford Spectrum Investors LLC   (2) (3) (4)

Explanation of Responses:
( 1)  The Common Stock and Warrants are held directly by Kappa Investors LLC ("Kappa").
( 2)  The Common Stock and Warrants are held directly by Wexford Spectrum Investors LLC ("WSI", and together with Kappa, the "Funds").
( 3)  This form is jointly filed by Wexford Capital LP ("Wexford"), Charles E. Davidson ("Davidson"), Joseph M. Jacobs ("Jacobs") and Wexford GP LLC ("Wexford GP"). The securities shown as beneficially owned by Davidson, Jacobs, Wexford GP and Wexford, reflect securities owned of record by the Funds. Wexford serves as manager for the Funds and as such may be deemed to share beneficial ownership of the securities beneficially owned by the Funds, but disclaims such beneficial ownership to the extent such beneficial ownership exceeds its pecuniary interest. (*continued under Footnote (4) below).
( 4)  (*continued from Footnote (3) above) Wexford GP, as the general partner of Wexford, may be deemed to share beneficial ownership of the securities beneficially owned by the Funds, but disclaims such beneficial ownership to the extent such beneficial ownership exceeds its pecuniary interest. Messrs. Davidson and Jacobs, as the controlling persons of Wexford GP, may be deemed to share beneficial ownership of any securities beneficially owned by the Funds for which Wexford serves as manager, but disclaim such beneficial ownership to the extent such beneficial ownership exceeds their pecuniary interest.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
WEXFORD CAPITAL LP
411 WEST PUTNAM AVENUE
SUITE 125
GREENWICH, CT 06830

X

JACOBS JOSEPH
C/O WEXFORD CAPITAL LP
411 WEST PUTNAM AVENUE, SUITE 125
GREENWICH, CT 06830

X

Wexford GP LLC
C/O WEXFORD CAPITAL LP
SUITE 125
GREENWICH, CT 06830

X

DAVIDSON CHARLES E
C/O WEXFORD CAPITAL LP
411 WEST PUTNAM AVE.
GREENWICH, CT 06830

X


Signatures
Arthur H. Amron, Vice President and Assistant Secretary of Wexford GP LLC, the General Partner of Wexford Capital LP 1/25/2013
** Signature of Reporting Person Date

Arthur H. Amron, Vice President and Assistant Secretary of Wexford GP LLC 1/25/2013
** Signature of Reporting Person Date

Charles E. Davidson 1/25/2013
** Signature of Reporting Person Date

Joseph M. Jacobs 1/25/2013
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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