By Peter McKay

Weakness in health-care stocks weighed on the broader market Wednesday afternoon, leaving major indexes near the flat line as investors assessed a new call by President Obama to pass federal health-care legislation.

The market had rallied through most of the session, aided by favorable readings of jobs, service-sector activity, and the Federal Reserve's beige book of regional indicators. But the early gains dried up late in the session.

The Dow Jones Industrial Average (DJI) was up more than 60 points at its morning high but recently skirted between gains and losses. The measure was off seven points at 10,399.33, failing for the second day in a row to hold a move into positive territory for the year to date. If the Dow's current performance holds through the close, the blue-chip measure would be off 29 points for 2010.

The Nasdaq Composite Index (RIXF) slipped 0.1%. The S&P 500 (SPX) was up 0.1%, helped by a 1.1% gain in its basic-materials sector.

Pfizer Inc. (PFE) was the Dow's weakest component, off 1.6% after Medivation said its experimental Alzheimer's disease treatment Dimebon, which was in development with Pfizer, failed to show effectiveness in a large late-stage study. The news sent shares of Medivation (MDVN), which is not a Dow stock, plunging 66.9%.

Looking to push the "long and wrenching debate" over health care into its final stages, Obama asked lawmakers to schedule a vote on overhaul legislation "in the next few weeks."

Health insurers clung to gains after the speech but a number of drug distributors lost ground after Obama proposed measures to eliminate "wasteful" subsidies of pharmaceutical companies.

For months, health-care stocks have been sensitive to the possibility that any possible changes in Washington might hinder private providers' profit-making ability. The sector picked up a bit in January when Republicans expanded their Senate minority - a development that was thought by many to dim the prospects of passage of a health bill. But on Wednesday, investors had to grapple with the prospects that it might get through after all.

"A lot of the legislative news has already been priced into these stocks, so they're not exactly getting killed," said Todd Leone, head trader at Cowen & Co. "But at the same time, passage of any bill would be a negative for the sector if and when it happens. I think we're looking at about a 50-50 possibility of that at this point."

The session's strong economic data helped basic-materials and industrial stocks, which tend to be sensitive to the pace of global recovery. Caterpillar Inc. (CAT) and Alcoa Inc. (AA) were up about 1.4% each, while General Electric Co. (GE) gained 0.9%.

Among stocks to watch, Novell (NOVL) surged 28% to $6.09, topping an offer price announced late Tuesday from hedge fund Elliott Associates and sparking speculation another software company or hedge fund could step in with a higher bid.

Volume was light, with composite turnover in New York Stock Exchange-listed companies recently hitting 3.4 billion shares.

The euro strengthened versus the dollar following Greece's announcement of an austerity plan meant to address its debt crisis. The U.S. Dollar Index (DXY) was recently off 0.7%.

The dollar's weakness helped to push up prices of raw materials. The broad Dow Jones-UBS Commodity Index was up 1.1%, helped by a 1.5% jump in oil. Crude futures rose for a second straight day, up $1.19 to $80.87 a barrel, the highest close in nearly two months.

Treasury prices edged lower. The benchmark 10-year note was off 3/32 to 3.621%.

 
 
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