Insightful Corporation (NASDAQ:IFUL), a leading provider of predictive analytics and reporting solutions, announced today the company will host a free webinar titled �Graphical Evaluation for Cardiovascular Safety Data in Clinical Trials� on July 17, 2008 from 8:30 to 9:30 a.m., Pacific Daylight Time. Dr. Ihab G. Girgis, a principal scientist in the Advanced Modeling and Simulation group at Johnson & Johnson Pharmaceutical Research & Development, will lead the webinar. During the webinar, Dr. Girgis will explore the graphical evaluation of baseline QT clinical data and its modeling. Detecting the drug-induced effect on cardiac repolarization or QT interval�is a closely monitored safety element in drug development, and more recently, it has also been scrutinized in regulatory submissions. Length of the QT intervals can be influenced by a number of covariates, such as heart rate (HR), RR interval (RR= 60/HR), gender, and natural circadian rhythm. There are other unknown factors that influence this interval, making it highly variable across populations. As such, the analysis of these data is complex. In order to evaluate the effect of drug on QT interval, accurate modeling of drug-free baseline QT becomes an important first step. Subsequent changes to this baseline model after the administration of an investigational drug can reflect the effect of the investigational drug on the QT/QTc interval. To register for this event, please visit : www.insightful.com/news_events/webcasts/2008/07grapheval/default.asp About Insightful Insightful Corporation (NASDAQ:IFUL) is a provider of predictive analytics and reporting solutions. Insightful products S-PLUS�, Insightful Miner� and S-PLUS� Enterprise Server allow companies to perform sophisticated statistical data analysis and data mining and create high-quality graphics and reports. Insightful has been delivering industry-leading, high-ROI solutions to thousands of companies in financial services, life sciences, telecommunications, and manufacturing, plus government and research institutions, for 20 years. Headquartered in Seattle, Insightful has offices in New York, North Carolina, Switzerland, the United Kingdom, France and Hong Kong, with distributors around the world. For more information, visit www.insightful.com, email info@insightful.com or call 1-800-569-0123.
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