Product sales increased 14% over third quarter 2007 to $201 million
SAN DIEGO, Oct. 21 /PRNewswire-FirstCall/ -- Amylin
Pharmaceuticals, Inc. (NASDAQ:AMLN) today reported financial
results for the quarter ended September 30, 2008. The Company
reported total revenue of $218.4 million for the third quarter,
including net product sales of $201.4 million, a 14% increase over
the same period in 2007. Net loss for the quarter ended September
30, 2008 was $77.7 million, or $0.57 per share. Net loss per share,
excluding an impairment loss on investments of $14.9 million, or
$0.11 per share, was $0.46 per share. "This quarter we reported
strong product sales in the face of an increasingly challenging
environment. Additionally we completed an exenatide once weekly
product supply agreement with Lilly that strengthens our balance
sheet and provides financial flexibility for the future," said
Daniel M. Bradbury, president and chief executive officer of Amylin
Pharmaceuticals. "We continue to manage the company towards
sustainable, profitable growth by driving BYETTA and SYMLIN
revenue, managing our expenses, and bringing exenatide once weekly
to market." Quarter ended September 30, 2008 Net product sales of
$201.4 million for the third quarter include $179.9 million for
BYETTA(R) (exenatide) injection and $21.5 million for SYMLIN(R)
(pramlintide acetate) injection. This represents a 14% increase
over net product sales of $177.4 million for the same period in
2007. Revenues under collaborative agreements were $17.0 million
for the quarter ended September 30, 2008, compared to $12.6 million
for the same period in 2007. The increase reflects higher
cost-sharing payments from Lilly for development expenses for
BYETTA and exenatide once weekly. Selling, general and
administrative expenses increased to $99.7 million for the quarter
ended September 30, 2008, compared to $87.7 million for the same
period in 2007. The increase reflects costs associated with the
Company's expanded field force, investments in market development
activities for exenatide once weekly and continued investment in
promotional activities for BYETTA and SYMLIN. Research and
development expenses increased to $73.5 million for the quarter
ended September 30, 2008, compared to $61.5 million for the same
period in 2007. The increase primarily reflects increased
development expenses for exenatide once weekly and increased
expenses for the Company's obesity development programs. Non-GAAP,
research and development expenses net of cost sharing payments
increased to $57.5 million for the quarter ended September 30, 2008
compared to $49.9 million for the same period in 2007.
Collaborative profit sharing, which represents Lilly's share of the
gross margin for BYETTA, was $80.6 million for the quarter ended
September 30, 2008, compared to $75.0 million for the same period
in 2007. Loss on impairment of investments was $14.9 million for
the quarter ended September 30, 2008. This primarily represents
recognized impairment losses on the Company's equity investments in
privately held entities of $9.0 million and an impairment loss of
$5.9 million associated with a corporate debt security in the
Company's investment portfolio. The net book value of the Company's
remaining equity investments in privately held entities was less
than $5.0 million at September 30, 2008. There was no comparable
expense for the quarter ended September 30, 2007. Net loss for the
quarter ended September 30, 2007 was $77.7 million, or $0.57 per
share, compared to $39.8 million, or $0.30 per share, for the same
period in 2007. Third quarter highlights Highlights of Amylin's
third quarter and recent activities include: BYETTA -- Initiated
co-promotion of BYETTA with third party Lilly primary care sales
force, increasing the sales force promoting BYETTA by 40%.
Exenatide Once Weekly -- Executed an exenatide once weekly supply
agreement with Lilly, under which Lilly will make an initial
payment of $125 million to Amylin in the fourth quarter of 2008. In
addition, Lilly extended a $165 million line of credit to Amylin.
These agreements underscore Amylin's and Lilly's commitment to the
successful commercialization of exenatide once weekly, strengthen
Amylin's balance sheet and provide additional financial
flexibility. -- Announced publication of DURATION-1 results in The
Lancet. The study showed that continuous steady state levels of
exenatide, on board 24 hours a day, seven days a week, provided
durable glycemic control and sustained weight loss. -- Completed
enrollment of DURATION-2, which compares exenatide once weekly
against a thiazolidinedione and a DDP-4 inhibitor on a background
of metformin therapy. Obesity Program -- Completed enrollment of a
phase 2B study to evaluate different dosing combinations of
pramlintide and metreleptin. The objective of this dose-ranging
study is to support dose selection for phase 3, and to guide the
development of a delivery system for this combination regimen. Nine
months ended September 30, 2008 Total revenues for the nine months
ended September 30, 2008 were $637.6 million. This includes net
product sales of $580.4 million, including $515.9 million for
BYETTA and $64.5 million for SYMLIN. This compares to net product
sales of $506.7 million, consisting of $459.7 million for BYETTA
and $47.0 million for SYMLIN for the same period in 2007. Revenues
under collaborative agreements were $57.2 million for the nine
months ended September 30, 2008, compared to $52.2 million for the
same period in 2007. The increase reflects higher cost-sharing
payments from Lilly for development expenses for BYETTA and
exenatide once weekly. Collaborative revenues for the nine months
ended September 30, 2007 included $15.0 million in milestones
earned upon Lilly's launch of BYETTA in the European Union.
Selling, general and administrative expenses increased to $309.0
million for the nine months ended September 30, 2008, from $268.6
million for the same period in 2007. The increase reflects costs
associated with the Company's expanded field force, increased
promotional activities for BYETTA and SYMLIN, investments in market
development activities for exenatide once weekly and increases in
business infrastructure. Research and development expenses
increased to $226.1 million for the nine months ended September 30,
2008, from $192.7 million for the same period in 2007. The increase
primarily reflects increased development expenses for exenatide
once weekly and continued investment in the Company's obesity
programs. Non-GAAP, research and development expenses net of cost
sharing payments increased to $172.1 million for the quarter ended
September 30, 2008 compared to $158.7 million for the same period
in 2007. Collaborative profit sharing was $229.4 million for the
nine months ended September 30, 2008, compared to $212.3 million
for the same period in 2007. Net loss was $211.3 million, or $1.54
per share for the nine months ended September 30, 2008, compared to
$134.2 million, or $1.02 per share, for the same period in 2007.
Conference Call Amylin will Webcast its Quarterly Update Conference
Call today at 5:00 p.m. ET/2:00 p.m. PT. The call will be Webcast
live through Amylin's corporate Web site, http://www.amylin.com/,
and a recording will be made available following the close of the
call. Daniel M. Bradbury, Amylin's president and chief executive
officer, will lead the call. During the call, the Company plans to
provide further details underlying its third quarter financial
results, and information regarding assumptions for the remainder of
2008 operations. For those without access to the Internet, the live
call may be accessed by phone by calling (888) 536-6007
(U.S./Canada) or (706) 758-4632 (international), Conference ID#
68128288. A replay of the call will also be available by phone
beginning approximately two hours after the close of the call and
can be accessed at (800) 642-1687 (U.S./Canada) or (706) 645-9291
(international), Conference ID# 6812822. Note Regarding Use of
Non-GAAP Financial Measures Amylin reports non-GAAP, research and
development expenses net of cost-sharing payments, which is a
non-GAAP financial measure. The Company believes that investors'
understanding of Amylin's net investment in research and
development activities is enhanced by this disclosure. In addition,
the Company refers to this non-GAAP financial information with its
analysis of the Company's financial performance. This non-GAAP
financial information should be considered in addition to, and not
as a substitute for, or superior to, financial measures calculated
in accordance with GAAP. A reconciliation of reported GAAP research
and development expenses to non-GAAP research and development
expenses, net of cost-sharing payments, is provided in the table
that follows (in thousands, unaudited): Quarter ended Nine months
ended September 30, September 30, 2008 2007 2008 2007 GAAP research
and development expenses $73,466 $61,457 $226,073 $192,712
Cost-sharing payments (15,927) (11,566) (53,983) (34,013) Non-GAAP
research and development expenses, net of cost sharing payments
$57,539 $49,891 $172,090 $158,699 About Amylin Amylin
Pharmaceuticals is a biopharmaceutical company committed to
improving lives through the discovery, development and
commercialization of innovative medicines. Amylin has developed and
gained approval for two first-in-class medicines for diabetes,
SYMLIN(R) (pramlintide acetate) injection and BYETTA(R) (exenatide)
injection. Amylin's research and development activities leverage
the Company's expertise in metabolism to develop potential
therapies to treat diabetes and obesity. Amylin is headquartered in
San Diego, California with over 2,000 employees nationwide. Further
information on Amylin Pharmaceuticals is available at
http://www.amylin.com/. This press release contains forward-looking
statements about Amylin, which involve risks and uncertainties. Our
actual results could differ materially from those discussed herein
due to a number of risks and uncertainties, including risks that
BYETTA or SYMLIN may be affected by competition, unexpected new
data, technical issues, or manufacturing and supply issues; risks
that our financial results may fluctuate significantly from period
to period and may not meet market expectations; risks that any
financial guidance we provide may not be accurate; risks that our
clinical trials will not be completed when planned or may not
replicate previous results; risks that our preclinical studies may
not be predictive; risks that our NDAs for product candidates or
sNDAs for label expansion requests, such as exenatide once weekly
NDA or the BYETTA monotherapy sNDA, may not be submitted timely or
receive FDA approval; risks that we may not be able to complete our
manufacturing facility on a timely basis; and other risks inherent
in the drug development and commercialization process. Commercial
and government reimbursement and pricing decisions and the pace of
market acceptance may also affect the potential for BYETTA or
SYMLIN. These and additional risks and uncertainties are described
more fully in the Company's recently filed Form 10-Q. Amylin
disclaims any obligation to update these forward-looking
statements. (Financial information to follow) AMYLIN
PHARMACEUTICALS, INC. CONSOLIDATED STATEMENTS OF OPERATIONS (in
thousands, except per share data) (unaudited) Quarter ended Nine
months ended September 30, September 30, 2008 2007 2008 2007
Revenues: Net product sales $201,364 $177,391 $580,420 $506,731
Revenues under collaborative agreements 16,998 12,637 57,198 52,228
Total revenues 218,362 190,028 637,618 558,959 Costs and expenses:
Cost of goods sold 23,395 13,750 70,101 43,322 Selling, general and
administrative 99,676 87,718 309,007 268,626 Research and
development 73,466 61,457 226,073 192,712 Collaborative profit
sharing 80,567 75,026 229,418 212,328 Total costs and expenses
277,104 237,951 834,599 716,988 Operating loss (58,742) (47,923)
(196,981) (158,029) Interest (expense) income, net (4,036) 8,165
590 23,834 Loss on impairment of equity method and available for
sale investments (14,943) - (14,943) - Net loss $(77,721) $(39,758)
$(211,334) $(134,195) Net loss per share - basic and diluted
$(0.57) $(0.30) $(1.54) $(1.02) Shares used in computing net loss
per share - basic and diluted 137,389 132,805 136,799 131,884
AMYLIN PHARMACEUTICALS, INC. CONDENSED CONSOLIDATED BALANCE SHEETS
(in thousands) (unaudited) September 30, December 31, 2008 2007
Assets Cash, cash equivalents and Short-term investments $805,451
$1,130,415 Accounts receivable, net 64,130 73,579 Inventories, net
98,508 100,214 Other current assets 28,422 32,100 Property, plant
and equipment, net 600,204 390,301 Other assets 35,883 47,602 Total
assets $1,632,598 $1,774,211 Liabilities and stockholders' equity
Current liabilities $278,909 $287,284 Other liabilities, net of
current portion 32,661 34,109 Long-term debt, net of current
portion 876,563 900,000 Stockholders' equity 444,465 552,818 Total
liabilities and stockholders' equity $1,632,598 $1,774,211
DATASOURCE: Amylin Pharmaceuticals, Inc. CONTACT: Financial,
Michael York, Senior Director, Investor Relations, +1-858-458-8602,
, or Media, Alice Izzo, Executive Director, Corporate Affairs,
+1-858-642-7272, , both of Amylin Pharmaceuticals, Inc. Web Site:
http://www.amylin.com/
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