TIDMOCTP

RNS Number : 5026E

Oxford Cannabinoid Tech.Holdings

11 March 2022

Oxford Cannabinoid Technologies Holdings plc

("OCTP", or the "Company")

Posting of Circular

&

Notice of Requisitioned General Meeting

Further to the announcement of 4 March 2022, Oxford Cannabinoid Technologies Holdings plc (LSE: OCTP, OTCQB: OCTHF), the pharmaceutical company developing prescription cannabinoid medicines for approval by global regulatory agencies and targeting the US$ multi-billion pain market, announces that it will today be posting a circular (the "Circular") to Shareholders convening a requisitioned general meeting (the "Requisitioned General Meeting").

This follows the receipt of a letter from GHS Capital Limited ("GHS Capital"), the holder of 78,146,151 ordinary shares of GBP0.01 each in the issued share capital of the Company ("Ordinary Shares"), representing approximately 8.14 per cent. of the Company's issued share capital, requisitioning a general meeting of the Company, as announced on 18 February 2022.

The Requisitioned General Meeting will be held at the offices of Penningtons Manches Cooper LLP, 125 Wood Street, London EC2V 7AW at 10.30 a.m. on 6 April 2022.

At the Requisitioned General Meeting Shareholders will be asked to consider the following ordinary resolutions:

1. THAT James Brodie be and is hereby appointed as a director of the Company (with such appointment taking immediate and simultaneous effect).

2. THAT Richard Bedford be and is hereby appointed as a director of the Company (with such appointment taking immediate and simultaneous effect).

3. THAT Richard Grethe be and is hereby appointed as a director of the Company (with such appointment taking immediate and simultaneous effect).

   4.     THAT Julie Pomeroy be and is hereby removed as a director of the Company. 
   5.     THAT Cheryl Dhillon be and is hereby removed as a director of the Company. 
   6.     THAT John Lucas be and is hereby removed as a director of the Company. 
   7.     THAT Neil Mahapatra be and is hereby removed as a director of the Company. 
   8.     THAT Bishrut Mukherjee be and is hereby removed as a director of the Company. 
   9.     THAT Richard Hathaway be and is hereby removed as a director of the Company. 

10. THAT any person appointed as a director of the Company since the date of the requisition of the Requisitioned General Meeting at which this resolution is proposed, and who is not one of the persons referred to in the resolutions numbered 1 through 10 (inclusive) above, be and is hereby removed as a director of the Company.

The Board's unanimous recommendation is for shareholders to vote AGAINST all of the resolutions being proposed by GHS Capital.

As announced on 4 March 2022, the Company is in receipt of irrevocable undertakings to vote AGAINST the proposed resolutions from Shareholders (including those of the Board) of 446,632,048 Ordinary Shares, representing approximately 46.5 per cent. of the issued share capital of the Company.

Extracts from the Circular are set out below and should be read in conjunction with the Circular. A copy of the Circular will shortly be available from the Company's website: www.oxcantech.com/investor-financial-results-centre and in hard copy form at the Company's registered office

at  Maddox House, 1 Maddox Street, London W1S 2PZ. It is also   available for inspection at www.fca.org.uk/markets/primary-markets/regulatory-disclosures/national-storage-mechanism . 

This announcement contains inside information for the purposes of Article 7 of EU Regulation 596/2014 (which forms part of domestic UK law pursuant to the European Union (Withdrawal) Act 2018).

The Directors of the Company accept responsibility for the content of this announcement.

Enquiries:

 
 Oxford Cannabinoid Technologies           +44 (0)20 3034 2820 
  Holdings plc                              john@oxcantech.com 
  Dr John Lucas (CEO)                       clarissa@oxcantech.com 
  Clarissa Sowemimo-Coker (COO) 
 Cairn Financial Advisers LLP 
  Emily Staples                             +44 (0)20 7213 0897 
  Jo Turner                                  +44 (0) 20 7213 0885 
 Walbrook PR Limited                       +44 (0)20 7933 8780 
  Paul Vann                                 +44 (0)7768 807631 
  Nicholas Johnson                          oxcantech@walbrookpr.com 
  Harbor Access LLC (US/OTCB enquiries)     +1 (203) 862 0492 
  Jonathan Paterson                         Richard.Leighton@harboraccessllc.com 
  Richard Leighton 
 

About Oxford Cannabinoid Technologies Holdings Plc :

Oxford Cannabinoid Technologies Holdings plc is the holding company of Oxford Cannabinoid Technologies Ltd, a pharmaceutical company developing prescription cannabinoid medicines for approval by key medicines regulatory agencies worldwide and targeting the U$ multi-billion pain market (together the "Group"). Cannabinoids are compounds found in the cannabis plant that have been shown to have a range of therapeutic effects on the body, including pain relief. The Group has a clearly defined path to commercialisation, revenues and growth. The Group is developing drug candidates through clinical trials to gain regulatory approval (FDA/MHRA/EMA) that will enable medical professionals to prescribe them with confidence.

The Group's portfolio aims to balance risk, value and time to market, whilst ensuring market exclusivity around all its key activities. The Group's lead compound, OCT461201, is a highly potent and selective CB2 agonist and is being developed by OCT in a solid oral dosage form. OCT is conducting pre-clinical testing and development with clinical trials scheduled for Q1 2023. The Group's product pipeline also uses a balanced drug product strategy that employs both natural and synthetic compounds for the treatment of rare diseases and includes chemically modified phytocannabinoids with improved drug-like characteristics and a proprietary library of cannabinoids.

OCTP operates a partnership model with external academic and commercial partners.

Caution regarding forward looking statements

Certain statements in this announcement, are, or may be deemed to be, forward looking statements. Forward looking statements are identi ed by their use of terms and phrases such as "believe", "could", "should" "envisage", "estimate", "intend", "may", "plan", "potentially", "expect", "will" or the negative of those, variations or comparable expressions, including references to assumptions. These forward-looking statements are not based on historical facts but rather on the Directors' current expectations and assumptions regarding the Company's future growth, results of operations, performance, future capital and other expenditures (including the amount, nature and sources of funding thereof), competitive advantages, business prospects and opportunities. Such forward looking statements re ect the Directors' current beliefs and assumptions and are based on information currently available to the Directors.

LETTER FROM THE BOARD

Notice of Requisitioned General Meeting and unanimous recommendation of your Board to

VOTE AGAINST all Resolutions

   1.       INTRODUCTION 

On 18 February 2022, the Company received a notice ("Notice of Requisition") from Gavin Sathianathan in his capacity as Chairman, CEO and Director of GHS Capital Limited, which is the holder of 78,146,151 Ordinary Shares, representing approximately 8.14 per cent. of the issued ordinary share capital in the Company, requesting the Company to convene a general meeting of its Shareholders pursuant to section 303 of the Act.

The Notice of Requisition requires the Directors to convene a general meeting (the "Requisitioned General Meeting") for the purpose of proposing ordinary resolutions to remove Julie Pomeroy, Cheryl Dhillon, John Lucas, Neil Mahapatra, Bishrut Mukherjee and Richard Hathaway as Directors of the Company and to appoint James Brodie, Richard Bedford and Richard Grethe, as directors of the Company.

On 24 November 2021, following the Company's Annual General Meeting at which the entire Board was re-elected (save for Richard Hathaway who has only recently been appointed), Mr Sathianathan resigned from his role as a Non-Executive Director of the Company stating that he remained "fully supportive of the Company" and that he was looking forward "to playing an active role as a key shareholder in the future".

Your Board is not aware of any change in circumstances over the past three months since the Annual General Meeting that justify, in any sense, the Notice of Requisition and we deal, in detail, with each of the purported issues raised by Mr Sathianathan in paragraph 3 below. Since Admission, the Board has not deviated from the strategy set out in the Company's Prospectus and operationally, the Company has made good progress and is in strong financial health. Cash resources remain within forecast at approximately GBP11m as at the date of the Circular, with the Company on target to be in phase 1 clinical trials with both OCT461201 and OCT130401 by Q1 2023 which is anticipated by the Directors to drive value for the Company and its Shareholders.

Your Board believes that Mr Sathianathan's proposals should be firmly resisted in the interests of Shareholders as a whole and that all Shareholders should vote AGAINST the Requisitioned Resolutions. As announced on 4 March 2022, the Company is already in receipt of irrevocable undertakings from holders (including those of the Board) of 446,632,048 Ordinary Shares, representing approximately 46.5 per cent. of the issued share capital of the Company, to vote AGAINST the Requisitioned Resolutions.

A notice convening the Requisitioned General Meeting for 10.30 a.m. on 6 April 2022 is set out on page 14 of the Circular.

The purpose of this letter is to explain why your Board believes these proposals are wholly unacceptable and strongly believes that the Requisitioned Resolutions are not in the best interests of the Company and its Shareholders as a whole and, given the irrevocable undertakings already secured from Shareholders to vote against the Requisitioned Resolutions, regrets the unnecessary expense, waste of management time and damage to your Company caused by the actions of former Non-Executive Director Mr Sathianathan and GHS Capital Limited.

Accordingly, your Board recommends unanimously that Shareholders VOTE AGAINST THE REQUISITIONED RESOLUTIONS at the Requisitioned General Meeting.

   2.       REASONS GIVEN FOR THE REQUISITIONED GENERAL MEETING 

In accordance with the Act, the letter from Mr Sathianathan in his capacity as Chairman, CEO and Director of GHS Capital Limited setting out his reasons for requesting the Company to convene the Requisitioned General Meeting accompanies the Circular.

   3.       YOUR BOARD'S RESPONSE TO THE NOTICE OF REQUISITION 

Your Board believes that the Requisitioned Resolutions proposed by GHS Capital are completely without merit. They are also a distraction to the Board whose focus should be on continuing to execute the strategy communicated in the Prospectus it prepared in support of its admission to the standard segment of the Official List and to trading on the Main Market on 21 May 2021. Since Admission, the Board has not deviated from this stated strategy and the Directors believe that to change it at this time would be to destroy the key value in the Company when the building blocks have been put in place to create a successful participant in the pharmaceutical cannabinoid market.

In the following paragraphs, the Board discusses the operational status of the Company's wholly owned operating subsidiary Oxford Cannabinoid Technologies Ltd ("OCT") and the Company's share price performance, and addresses each point made in the statement by GHS Capital.

A. Summary of the operational status of the Group communicated via various announcements since Admission

The Company has made strong progress since Admission and is on track to complete all workstreams outlined in the Prospectus. Specific detail is provided on each drug development programme below:

-- Programme 1 (OCT461201): OCT461201 has progressed through pre-clinical development, in-line with plans communicated at Admission. The Group has entered into research contracts with Voisin Consulting SARL and a subsidiary of Evotec SE for manufacturing, development and compound crystallisation, as preparation for phase 1 clinical trials continues in earnest. The Group expects to start phase 1 clinical trials in early Q1 2023 rather than late Q3 2022, a result of technical issues associated with scale manufacturing that necessitated additional compound optimisation. However, at this time the Board does not believe that this will impact either the anticipated time to phase 2 clinical trials nor the ultimate time to market;

Most importantly, as outlined in the Company's announcement of 8 March 2022, the results of a recent pre-clinical efficacy study before human trials show OCT461201 successfully reduces pain in a pre-clinical animal model of Chemotherapy Induced Peripheral Neuropathy ("CIPN") induced by paclitaxel, a widely used chemotherapy agent. Two common symptoms of CIPN are pain caused by innocuous stimuli, like light touch (mechanical allodynia) and heat or cold (thermal hyperalgesia). In the study, OCT461201 significantly reduced pain from both mechanical allodynia and thermal hyperalgesia compared to untreated animals. This is a positive result: whilst a compound's path through human clinical trials always has uncertainty, the Directors believe the results will translate to humans. It should also be noted that previous animal safety data suggests that a three times more concentrated dose of OCT461201 could have been administered. The Company's Chief Executive Officer, John Lucas, was primarily responsible for the identification, negotiation, licensing and development of OCT461201;

-- Programme 2 (OCT 130401): The Company's other lead programme has also progressed in-line with the plans communicated at Admission. The Group has entered into development agreements with Charles Rivers Laboratories Edinburgh Ltd, Purisys LLC, and OZ UK Ltd, as OCT130401 and its inhaler delivery device are prepared for phase 1 clinical trials, anticipated in Q4 2022. There has been a short delay in development time (from Q3 2022), driven by partners' capacity challenges caused by Covid, but the Board does not currently believe that this will affect the time to phase 2 clinical trials, nor the ultimate time to market. The Group has also announced the orphan indication Trigeminal Neuralgia as the initial target for OCT130401, an indication in the growing neuralgia market, which overall is worth approximately $1.8 billion. The Directors believe that this second primary programme is as exciting as OCT461201, and being a phytocannabinoid combination, adds balance to the Company's drug development strategy;

-- Programmes 3 & 4: with regards to its earlier-stage development programmes, the Company has surpassed the deliverables communicated to investors at Admission. Cannabinoid derivatives are at the core of both programmes and last September, the Company announced the Group's exclusive agreement with Canopy Growth Corporation ("Canopy Growth" or "Canopy") for its pharmaceutical cannabinoid derivative library, comprising 335 derivatives and 14 patent families. This has jump-started both development programmes, with multiple screening initiatives already underway across an expanded therapeutic area set (including pain, neurology, and oncology). The Group is working with the organisation that previously synthesised the compounds for Canopy Growth (leveraging existing knowledge) and the drug development agreement signed with Oxford Stemtech Ltd ("Stemtech") is significant, with Stemtech's cutting-edge in-vitro "pain-in-a-dish" model (using human adult stem cells) allowing for high-throughput experiments to be completed cost effectively.

Noting that there has been no deviation in strategy to that set out in the Prospectus it is disappointing to receive the Notice of Requisition, requested by a Shareholder who previously supported this same strategy from before Admission up to as recently as four months ago. Operationally, the Company has made good progress since Admission and is in strong financial health. Cash resources remain within forecast at approximately GBP11m as at the date of the Circular, with the Company on target to be in phase 1 clinical trials with both OCT461201 and OCT130401 by Q1 2023 which is anticipated by the Directors to drive value for the Company and its Shareholders.

   B.      Share Price Performance 

The share price performance of the Company since Admission is a huge disappointment to the Board. However, we neither believe that this represents the value of the Company nor is it a function of poor strategy or any issue that is intrinsic to the Company. The Board believes that the share price has largely decreased due to a poor market backdrop and selling from short-term investors hoping to make a quick return in the cannabis market. We do not believe that the price is indicative of the operational or financial health of the business nor the outlook in the medium term and beyond. In particular:

-- Market backdrop: the market backdrop for all London-listed cannabis companies has been extremely poor over the last nine months. On average, between Admission and 18 February 2022 (the date of the Notice of Requisition), the share prices of the Company's London-listed cannabis-related peers have fallen by approximately 47 per cent. (see chart below). Shares in biotechnology companies have also fallen (with the Nasdaq biotechnology index having fallen by approximately 14% over the same period). As such, being both a cannabinoid company and a biotechnology business, the Company has been caught in a "perfect storm" of negative market performance. This goes some way to explaining share price performance since Admission, but the Directors believe that it is not representative of the long-term prospects for the Company;

-- Cash to reach value inflection: when assessing the actual prospects of the Company, your Board is of the view that the single most important criteria is that the Company has the necessary capital required to progress its drug development activities to reach key value inflection points. These inflection points are the completion of phase 1 clinical trials for the two primary drug programmes. We do not currently believe that there will be any requirement for additional capital raises in order for these milestones to be met;

-- Positioning: The Board believes that the Company's positioning remains a point of difference amongst its London-listed cannabis peers. In a cannabis market where unlicensed medicines are abundant and unproven, the Company's underlying philosophy is unchanged and consistent: that it is only by developing cannabinoid medicines through the existing channels of drug development that the medical community can have the confidence to prescribe in volume. The agreements that the Group has signed to date reflect this core ethos: we have partnered with organisations that represent the gold-standard in pharmaceutical development. The Board believes that this positioning will be of increasing value as the Company's drug programmes progress and drive share price appreciation in the medium and long term;

-- Selling pressure: it is also worth noting that the selling activity in the Company's shares since Admission has contributed to a constant downwards pressure on the share price. We understand that this consistent selling presence has been an impediment to any share buying momentum in the Ordinary Shares.

As an early stage pharmaceutical business, the Company has always been positioned as a long-term investment. This has not changed: the path of drug development is necessarily long, and biotechnology companies typically face challenges associated with a paucity of share price catalysts between developmental milestones. However, the Board does not believe that this is representative of the medium and long term prospects for the Company.

   C.         Addressing the Notice of Requisition 

As set out above, the Board believes that the Requisitioned Resolutions proposed by GHS Capital are without merit, opportunistic, and poorly considered. We address each of the points made in turn:

-- Strategic Review: it is disappointing to see a request for a strategic review. The Company's strategy remains the same as that communicated at Admission and is in line with the current trends in cannabinoid drug development. Our strategy aims to employ a balanced approach that combines previously successful strategies (e.g. targeting orphan indications) with new strategies enabled by recent advances in cannabinoid research (e.g. more focus on individual molecules, cannabinoid derivatives and novel receptors). This has already started to generate success: as announced on 8 March 2022, pre-clinical data for OCT461201 suggests a positive dose dependant effect in CIPN, which affects, on average, an estimated 60 per cent. of people undergoing chemotherapy at 3 months, our phytocannabinoid inhaler continues development for Trigeminal Neuralgia, an orphan indication, and as previously announced, Canopy Growth (one of the largest cannabis firms in the world) has entrusted the Company with its library of cannabinoid derivative compounds, providing strong validation of the Company's derivative strategy;

We strongly believe that there is no need for the Company to change direction and we continue to execute on exactly the strategy that was outlined at Admission (which Mr Sathianathan previously voted for whilst a Non-Executive Director of the Company). Any deviation from this strategy would likely immediately negate the financial investment that has been made into each development programme and cause significant delays in taking any drugs to market. As set out above, the Company has already received irrevocable undertakings from Shareholders holding 46.5% of the Ordinary Shares to vote against the Requisitioned Resolutions - these are Shareholders that are long term investors in the Company and their support is key;

-- Reduction of Costs: this point is entirely without merit and unjustified. Firstly, as shown in the interim financial statements, the administrative costs of the Company are under constant scrutiny and efforts to generate cost savings are on-going. For example, as set out in the Interim Results for the six months ended 30 November 2021, the Company has given notice on its London office, expiring 31 March 2022, which is expected to generate cost savings of circa GBP130k per year. The Company also terminated a services agreement with Kingsley Capital Partners LLP in December 2021, generating further cost savings. Secondly, the anticipated costs were drawn-up in detail, in preparation for Admission, and were agreed to by the Company's advisers and approved by the Board, (including Mr Sathianathan when he was a Non-Executive Director). Finally, as announced on 4 March 2022, in light of the number of irrevocable undertakings received, we gave Mr Sathianathan the opportunity to withdraw the Notice of Requisition in an attempt to avoid unnecessary expense but he declined to engage with us;

-- Replacement of Directors: it is disappointing to see Mr Sathianathan actively championing a reduction of diversity with his proposed replacement directors. We firmly believe that none of the Directors need to be replaced and, indeed, all of them, save for Richard Hathaway who has only recently been appointed, were re-elected at the Company's Annual General Meeting on 24 November 2021, just over three months ago. The Board already comprises the skillsets required to guide the business past the completion of clinical trials and through to the marketing authorisation of its drugs. Taking them in turn:

John Lucas - in John, we have a seasoned CEO who has identified and in-licensed a compound with significant potential, driven the development of all four drug programmes, is taking OCT's first two drug programmes successfully through pre-clinical development, and who was also instrumental in negotiating the agreement with Canopy Growth for its pharmaceutical cannabinoid derivative library, comprising 335 derivatives and 14 patent families , which has added significant momentum to the Company's third and fourth programmes;

Cheryl Dhillon - in Cheryl the Company is fortunate to have an independent Non-Executive Director who is an experienced pharmaceutical executive with three decades of experience in companies including Ares Serono Group, Elan Corporation Plc, Lorantis Ltd and a tenure of over 15 years with Otsuka Pharmaceutical Europe Ltd; part of the Otsuka family of companies. Cheryl's advice is already invaluable but will become even more so when the Company starts clinical trials in a few months;

Richard Hathaway - Richard is currently Corporate Development Director at FTSE-100 Imperial Brands plc where he is responsible for leading M&A activity and other strategic initiatives and projects across the business. He has extensive experience of auditing and advising public and private companies across a wide range of sectors, including transactions such as financing and restructuring, acquisitions and disposals;

Bishrut Mukherjee - Bishrut has played a valuable role to date in guiding the Company, not only in terms of its operational drug development activities but also in evaluating the strategic direction of the business. Following his resignation from Imperial Brands Ventures Limited in September 2021, he also provides valuable perspective as an independent Non-Executive Director and his wide range of experience within operational delivery, M&A, corporate strategy and investment analysis, principally across regulated industries including those of manufacturing, energy, pharmaceuticals and FMCG is an asset to the Board;

Neil Mahapatra - as the founder and previous Chairman, Neil retains a deep knowledge of the business, its history and strategy. Neil was responsible for approaching Oxford University and negotiating the Company's research agreement with Oxford University, launching the cannabinoid derivative creation programme as a result. He liaised with the UK Home Office to obtain OCT's first licence for cannabis handling and research and was responsible for securing all private funding for the Company aside from Imperial Brands and nearly 25 per cent. of funds at Admission (the remainder secured by a capital raising firm);

Julie Pomeroy - in Julie the Company has a skilled and balanced independent Non-Executive Chair with around 20 years' experience on the boards of publicly quoted companies. She is a Non-Executive Director at Dillistone Group Plc, an AIM quoted software business, where until September 2021 she was the group finance director and company secretary having joined in 2010. She also spent over 12 years as a non-executive director on two NHS Trust Boards. Julie is a Chartered Accountant and also a Chartered Director and brings governance experience for publicly listed companies;

-- Improve corporate governance: we strongly reject this criticism and believe it to be a generic request due to its absence of foundation. The Board places great emphasis on good corporate governance and, as set out in the Prospectus, has not only committed to comply with the Premium Listing Principles set out in Chapter 7 of the Listing Rules (notwithstanding that they only apply to companies with a Premium Listing) and to adopt and comply with the QCA Code on a comply or explain basis but, as set out in the 2021 Annual Report, the Company has complied with the QCA Code to date and has no intention to deviate from this. In addition, the Board is surprised that Mr Sathianathan would raise an issue such as this in a requisition notice rather than engage directly with the Board, either while he held the position of Non-Executive Director or subsequently, through GHS Capital, as a large Shareholder, where any concern he may have had could have been discussed and implemented if deemed appropriate W e note that at midnight on the day before the Company was required to post the Circular, Mr Sathianathan sent a letter to the Chair making various spurious allegations concerning the Board and the Company's operations. We will consider these in full and address them separately to the extent they merit a response.

   4.       IRREVOCABLE UNDERTAKINGS 

As announced on 4 March 2022, the Directors are pleased to report that they have received irrevocable undertakings (including those of the Board) to vote against the Requisitioned Resolutions from Shareholders representing approximately 46.5 per cent. of the Company's issued share capital.

   5.       NOTICE OF REQUISITIONED GENERAL MEETING 

A notice convening the Requisitioned General Meeting at which the Requisitioned Resolutions will be proposed is set out on page 14 of the Circular.

Shareholders are asked to note that in line with the most recent Institutional Shareholder Services' Proxy Voting Guidelines, effective for meetings on are after 1 February 2022, the Requisitioned General Meeting is being called on 21 days' notice rather than 14 days to enable Shareholders to have as much notice of the meeting with time for consideration as practicable.

   6.       ACTION TO BE TAKEN BY SHAREHOLDERS 

Shareholders who hold their Ordinary Shares in certificated form should check that they have received the following with the Circular:

   --      a Form of Proxy for use in relation to the Requisitioned General Meeting; and 

-- a reply-paid envelope for use in connection with the return of the Form of Proxy (in the UK only).

You are strongly encouraged to complete, sign and return your Form of Proxy in accordance with the instructions printed thereon so as to be received, by post or, during normal business hours only, by hand to the Company's Registrar, Computershare Investor Services PLC at The Pavilions, Bridgwater Road, Bristol BS99 6ZY , as soon as possible but in any event so as to arrive by not later than 10:30 a.m. on 4 April 2022 (or, in the case of an adjournment of the Requisitioned General Meeting, not later than 48 hours before the time fixed for the holding of the adjourned meeting (excluding any part of a day that is not a Business Day)).

Alternatively, register your vote online by visiting www.investorcentre.co.uk/eproxy and following the instructions provided.

   7.       DIRECTORS' RECOMMATION 

The Company's share price performance in the ten months since Admission is hugely disappointing. However, we believe this relates to short term issues which are not reflective of the fundamentals of the business: by continuing to execute on the strategy outlined at Admission, the Board believes that the Company's prospects remain positive, with enough capital raised at Admission to ensure that important milestones of bringing OCT461201 and through to completion of phase 1 clinical trials, as set out in the Prospectus, can be reached. The Board is proud of the support shown by its Shareholders, as evidenced by the irrevocable undertakings to vote against all the Requisitioned Resolutions already received representing over 46.5% of the issued share capital.

We believe that any Shareholders choosing to support the Requisitioned Resolutions would be endorsing values that are not consistent with the Company or its institutional investors: short-termism and a seemingly active desire to reduce diversity, promoted by a Shareholder who seems content for the Company to incur unnecessary and significant costs in the calling of the Requisitioned Meeting. None of these are values that the Company or its Board stands for.

The Company has a clear strategy for drug development. The Directors are committed to providing the management team with the time and resource necessary to execute on the strategy outlined in the Prospectus, without distractions such as these.

For all of the reasons given above, your Board believes that these proposals should be firmly resisted in the interests of Shareholders as a whole and that all Shareholders should vote AGAINST the Requisitioned Resolutions to be proposed at the Requisitioned General Meeting. As announced on 4 March 2022, the Company is already in receipt of irrevocable undertakings from holders (including those of the Board) of 446,632,048 Ordinary Shares, representing approximately 46.5 per cent. of the issued share capital of the Company, to vote AGAINST the Requisitioned Resolutions.

Yours sincerely

   Julie Pomeroy              Cheryl Dhillon              Richard Hathaway        Bishrut Mukherjee 

Chair NED NED NED

Neil Mahapatra John Lucas Karen Lowe Clarissa Sowemimo-Coker

   NED                             CEO                             CFO                             COO 

DEFINITIONS

The following de nitions apply throughout the Circular unless the context otherwise requires:

 
 "Act"                          the Companies Act 2006 (as amended); 
 "Admission"                    the admission of the Ordinary Shares 
                                 to the standard listing segment of the 
                                 Official List and to trading on the Main 
                                 Market that became effective on 21 May 
                                 2021; 
 "Board" or "Directors"         the directors of the Company as at the 
                                 date of the Circular, whose names are 
                                 set out on page 4 of the Circular; 
 "Business Day"                 any day (excluding Saturdays and Sundays) 
                                 on which banks are open in London for 
                                 normal banking business and the London 
                                 Stock Exchange is open for trading; 
 "Cellular Goods"               Cellular Goods plc; 
 "certificated" or "in          where an Ordinary Share is not in uncertificated 
  certificated form"             form (i.e. not held in CREST); 
 "Chair"                        the chair of the Board; 
 "CIPN"                         Chemotherapy Induced Peripheral Neuropathy; 
 "Company"                      Oxford Cannabinoid Technologies Holdings 
                                 PLC, a company incorporated in England 
                                 and Wales under company number 13179529; 
 "CREST"                        the relevant system for the paperless 
                                 settlement of trades and the holding 
                                 of uncerti cated securities operated 
                                 by Euroclear in accordance with the CREST 
                                 Regulations; 
 "CREST participant ID"         shall have the meaning given in the CREST 
                                 Manual; 
 "CREST Regulations"            the Uncertificated Securities Regulations 
                                 2001 (SI 2001/3755) including any enactment 
                                 or subordinate legislation which amends 
                                 or supersedes those regulations and any 
                                 applicable rules made under those regulations 
                                 or any such enactment or subordinate 
                                 legislation for the time being in force; 
 "Euroclear"                    Euroclear UK & International Limited; 
 "FCA"                          the Financial Conduct Authority of the 
                                 United Kingdom; 
 "Form of Proxy"                the form of proxy for use by Shareholders 
                                 in relation to the Requisitioned General 
                                 Meeting, enclosed with the Circular; 
 "FSMA"                         the Financial Services and Markets Act 
                                 2000 (as amended); 
 "Group"                        the Company and its subsidiaries (as 
                                 defined in the Act); 
 "Kanabo"                       Kanabo Group plc; 
 "Listing Rules"                the listing rules of the FCA; 
 "London Stock Exchange"        London Stock Exchange Group plc; 
 "Main Market"                  the London Stock exchange's main market 
                                 for listed securities; 
 "MGC Pharma"                   MGC Pharmaceuticals Limited; 
 "Notice of Requisition         the notice from Gavin Sathianathan in 
  "                              his capacity as Chairman, CEO and Director 
                                 of GHS Capital Limited dated 18 February 
                                 2022; 
 "Notice of Requisitioned       the notice convening the Requisitioned 
  General Meeting "              General Meeting as set out at the end 
                                 of the Circular; 
 " OCT "                        Oxford Cannabinoid Technologies Ltd, 
                                 the Company's wholly owned subsidiary; 
 " Official List "              the Official List maintained by the FCA; 
 "Ordinary Shares"              the ordinary shares of GBP0.01 each in 
                                 the capital of the Company in issue from 
                                 time to time; 
 "Oxford University"            The Chancellor Masters and Scholars of 
                                 the University of Oxford; 
 "Pharma C"                     Pharma C Investments PLC; 
 "Premium Listing"              a premium listing on the Official List 
                                 under Chapter 6 of the Listing Rules; 
 "Premium Listing Principles"   the listing principles, applicable to 
                                 a company with a Premium Listing, contained 
                                 in Chapter 7 of the Listing Rules; 
 " Prospectus "                 the prospectus dated published by the 
                                 Company in connection with Admission 
                                 dated 17 May 2021; 
 " Prospectus Regulation        the prospectus regulation rules of the 
  Rules "                        FCA made pursuant to 
                                 section 73A of the FSMA, as amended; 
 "QCA Code"                     the QCA Corporate Governance Code 2018, 
                                 published by the 
                                 Quoted Companies Alliance; 
 "Registrar"                    Computershare Investor Services PLC of 
                                 The Pavilions, Bridgwater, Road, Bristol 
                                 BS13 8AE; 
 "Regulatory Information        one of the regulated information services 
  Service"                       authorised by the FCA to receive, process 
                                 and disseminate regulatory information 
                                 in respect of listed companies; 
 "Requisitioned General         the Requisitioned General Meeting of 
  Meeting"                       the Company convened for 10:30 a.m. on 
                                 6 April 2022 or any adjournment thereof, 
                                 notice of which is set out at the end 
                                 of the Circular; 
 "Requisitioned Resolutions"    the resolutions to be proposed at the 
                                 Requisitioned General Meeting, the full 
                                 text of which are set out in the Notice 
                                 of Requisitioned General Meeting; 
 "Shareholders"                 the holders of Ordinary Shares, and the 
                                 term "Shareholder" shall be construed 
                                 accordingly; 
 "uncerti cated" or "uncerti    means recorded on the relevant register 
  cated form"                    or other record of the share or other 
                                 security concerned as being held in uncerti 
                                 cated form in CREST, and title to which, 
                                 by virtue of the CREST Regulations, may 
                                 be transferred by means of CREST; 
 "United Kingdom" or "UK"       the United Kingdom of Great Britain and 
                                 Northern Ireland; 
 "GBP" or "Pounds"              UK pounds sterling, being the lawful 
                                 currency of the United Kingdom; 
 "World High Life"              World High Life plc. 
 

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END

NOGBKDBQCBKKCND

(END) Dow Jones Newswires

March 11, 2022 05:00 ET (10:00 GMT)

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