FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

MAY ALAN RICHARD		 2. Issuer Name and Ticker or Trading Symbol

Hewlett Packard Enterprise Co [ HPE ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
EVP, Chief People Officer
(Last)          (First)          (Middle)

C/O HEWLETT PACKARD ENTERPRISE COMPANY, 1701 E. MOSSY OAKS ROAD		 3. Date of Earliest Transaction (MM/DD/YYYY)

6/3/2022
(Street)

SPRING, TX 77389
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 6/3/2022  M  94705 (1)A$10.48 405205 D  
Common Stock 6/3/2022  S  94705 (1)D$15.0794 (2)310500 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Restricted Stock Units  (3)1/7/2022  A   437.9242 (4)    (4) (4)Common Stock 437.9242  (4)33216.9242 D  
Restricted Stock Units  (3)1/7/2022  A   1253.7402 (5)    (5) (5)Common Stock 1253.7402  (5)91025.7402 D  
Restricted Stock Units  (3)1/7/2022  A   1527.6597 (6)    (6) (6)Common Stock 1527.6597  (6)107184.6597 D  
Employee Stock Option (right to buy) (7)$10.48 6/3/2022  M     94705  6/22/2016 (8)6/23/2023 (9)Common Stock 94705 $0 0 D  
Explanation of Responses:
(1) The reported transaction reflects the reporting person's exercise and sale of his employee stock options pursuant to the Order. The reporting person disclaims beneficial ownership to, and no longer reports as beneficially owned, any securities sold on behalf of, or owned by, his ex-spouse pursuant to the Order.
(2) The price in Column 4 is a weighted average price. The prices actually paid ranged from $15.0200 to $15.1250. Upon request, the reporting person will provide to the Issuer, any security holder of the Issuer, or the SEC staff information regarding the number of shares purchased at each price within the range.
(3) Each restricted stock unit represents a contingent right to receive one share of Issuer's common stock.
(4) As previously reported, on 12/10/19 the reporting person was granted 94,697 Restricted Stock Units ("RSUs"), 31,565 of which vested on 12/10/20, 31,566 of which vested on 12/10/21, and 31,566 of which will vest on 12/10/22. Dividend equivalent rights accrue with respect to these RSUs when and as dividends are paid on Issuer's common stock. The number of derivative securities in column 5 includes 212.1751 dividend equivalent rights at $17.130 per RSU credited to the reporting person's account on 01/07/22, and 225.7491 dividend equivalent rights at $16.100 per RSU credited to the reporting person's account on 04/08/22.
(5) As previously reported, on 12/10/20 the reporting person was granted 135,107 RSUs, 45,035 of which vested on 12/10/21, and 45,036 of which will vest on each of 12/10/22 and 12/10/23. Dividend equivalent rights accrue with respect to these RSUs when and as dividends are paid on Issuer's common stock. The number of derivative securities in column 5 includes 607.43960 dividend equivalent rights at $17.130 per RSU credited to the reporting person's account on 01/07/22, and 646.30060 dividend equivalent rights at $16.100 per RSU credited to the reporting person's account on 04/08/22.
(6) As previously reported, on 12/09/21 the reporting person was granted 105,657 RSUs, 35,219 of which will vest on each of 12/09/22, 12/09/23 and 12/09/24. Dividend equivalent rights accrue with respect to these RSUs when and as dividends are paid on Issuer's common stock. The number of derivative securities in column 5 includes 740.15410 dividend equivalent rights at $17.130 per RSU credited to the reporting person's account on 01/07/22, and 787.50560 dividend equivalent rights at $16.100 per RSU credited to the reporting person's account on 04/08/22.
(7) As reported in the Registration Statements on Form 10 filed by Issuer with the SEC, in connection with the spin-offs of Everett SpinCo, Inc. on 04/01/17 and Seattle SpinCo, Inc. on 09/01/17, equity-based awards granted by Issuer, prior to the spin-offs were converted to adjust the award in a manner intended to preserve the aggregate intrinsic value of the original award as measured immediately before and immediately after the spin-offs, subject to rounding. The adjusted equity award is otherwise subject to the same terms and conditions that applied to the original award immediately prior to the spin-offs, unless otherwise noted. The reporting person's equity based awards reflect the conversion adjustments.
(8) This option became exercisable beginning on this date.
(9) This option is no longer exercisable beginning on this date.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
MAY ALAN RICHARD
C/O HEWLETT PACKARD ENTERPRISE COMPANY
1701 E. MOSSY OAKS ROAD
SPRING, TX 77389

EVP, Chief People Officer
Signatures
Derek Windham as Attorney-in-Fact for Alan R. May6/7/2022
**Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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